BIOL 223 Lecture 3 Flashcards
Components of the Central Nervous System (CNS)
Brain & Spinal Cord. Contains Nucleus (cluster of nerve cell bodies) and Tracts (bundles of axons also known as nerve fibers)
Components of the Peripheral Nervous System (PNS)
Nerves & Ganglia (collection of nerve cell bodies outside CNS). Nerves bundles of axons also known as nerve fibers
Grey Matter
Primarly comprised of neurosomas (nerve cell bondies) and dendrites.
White Matter
Possesses Myelin that’s why it is white.
Myelin
lipid rich material that surrounds the nerve cell axons to insulate them.
Structures of a Neuron
Composed of dendrites (extension that receives information), Soma (cellbody), and Axon (transmits information from soma to another cell via action potentials)
Compare Nucleus and Ganglion
Essentially same thing just different locations
Compare Tract and nevrves
Essential same thing just different locations
Briefly describe the three basic functions of the nervous system
Sensation - Receiving information (stimulus)
Response - Motor function (voluntary or involuntary)
Integration - Information processing
Somatic Nervous System
Conscious perception and voluntary motor responses. Body Moving Skeletal tissue
Autonomic Nervous System
Visceral Motor System. Involuntary control of the body. Maintains homeostasis.
Enteric Nervous System
Can function without other nervous input. Smooth muscle and glandular tissue of the digestive system
Describe the Structure of the nerve cell body
Large nucleus and nucleolus. Perikaryon (Cytoplasm). Mitochondria (produce energy)
Describe the structure of dendrites
Short and highly branched processes extending from the cell body.
Describe the function of denderites
Dendritic spines receive information from other neurons. 80-90 percent of neuron surface area.
Describe the structure of axons
Single, long cytoplasmic process
Describe the function of axons
Propagates electrical signals - action potentials
Axoplasm
plasma membrane of the axon. Specialized to conduct electrical activity
Axolemma
Plasma membrane of the axon. Specialized to conduct electrical activity
pseudo-unipolar neurons
sensory neurons. Cell bodies found in ganglia
Bipolar Neurons
Olfactory epithelium and retinal cells - smell and vision
Multipolar neurons
majority of neurons
Glial Cell Function
Because neurons are so specialized they are not very good at other things and need help from glial cells. Support and protect neurons. Make up half the volume of the nervous system.
Astrocytes
In the CNS. Have large star shaped cell bodies with many processes that come from the cell body
Astrocytes function
Maintain Blood Brain Barrier. Create three-dimensional framework for CNS. Repair damaged nervous tissue. Guide Neuron Development. Control interstitial environment
oligodendrocytes
In the CNS. have small cell bodies with few processes. Many cooperate to form a myelin sheath around the axons in the CNS
Ependymal Cells
In the CNS. Form epithelium that lines central canal of spinal cord and ventricles of brain. Produce and monitor Cerebrospinal Fluid(CSF)
Microglia
In the CNS. Smallest and least numerous glia. Migrate through nervous tissue. Clean up cellular debris, waste and pathogens
Satellite cells
In the PNS. Surround ganglia. Regulate interstitial fluid around neurons. Help with limited repair
Schwann Cells
in the PNS. Form myelin sheath around axons. Neruolemma - Outer surface of schwann cell.
Steps of Temperature senstation
Sensation, intergration, response.
Non-specific ion channels
Allows for diffusion down the concentration gradient.
Ligand-Gated Ion Channels
Chemically gated. Opens only when a ligand binds to them
Mechanically Gated ion channels
Responds to a physical distortion of the plasma membrane
Voltage Gated Ion Channels
Open and close at specific voltages
Leak channels
resting membrane potential. Open and close randomly
Explain how resting membrane potential is and how it is set up/maintenance
Charge difference across the membrane surface. High concentration of sodium and chloride in extracellular fluid. High concentration of potassium and negatively charged proteins in intracellular fluid. Set up by a sodium potassium pump.
Explain the all-or-none principle
Any stimulus that changes the membrane potential to threshold causes an action potential
Generation of an action potential
Rapid voltage changes in membrane affects the entirety of the excitable membrane. Begins at initial segment (Axon hillock) of the axon.
Absolute refractory period
Membrane cannot generate another action potential. All voltage-gated sodium channels are already open or inactiviated
Relative refractory period
A strong stimulus can initiate another action potential. Begins when sodium channels regain resting condition. Continus until membran potential stabalizes.
Graded potentials
A graded potential is a change in the membrane potential that does not spread far from the site of stimulation