biofilm 1 - caries Flashcards
what is erosion caused by
- weak acids
what causes acid production
- bacteria biofilm and fermentable carbohydrates
what 4 factors are needed for caries
- saliva
- diet
- microbiota
- tooth
how does caries progress
- microorganisms adhere to tooth surface
- they survive and grow = not washed away with saliva)
- biofilm forms
- complex plaque forms = made up of whole range of species
- acid
- caries
what is streptococcus mutans
- microorganisms
- clear link between presence o it and caries
- linked to high sugar diet
- the odontopathogen
why is S mutans associated with caries
- glycolytic systems
- EPS/sucrose metabolism
- attachment mechanisms
- greater acidogenicity/aciduricity
- ecological competitiveness at low pH
- genomic characteristics
- has ability to modulate behaviour
does S mutans always cause caries
- not definite but there is a link
- some people can have it and no caries, other can not have it and still have caries
what factors relate to the cariogenicity of s mutans
- produces water soluble and insoluble extracellular polysaccharides from sucrose which help in the colonisation of tooth surfaces by consolidating microbial attachment
- ability to initiate and maintain microbial growth and to continue acid production in sites of low pH
- rapid metabolism of sugars to lactic and other acids
- can attain critical pH for enamel demineralisation quicker than any other bacteria
- produces intracellular polysaccharide which acts as food store when dietary carbohydrates are low
what are genitic contributions to caries devleopment
- salivary composition and constituents may elevate or depress caries risk
what study proved that fermentable carbohydrate are important for caries
-vipeholm study = 1945-1955
what are some cariogenic foods
- crisps
- biscuits
- cooked starches = stick around on teeth for longer
what is important for determining cariogenic potential
- oral retentiveness
what factors help remineralisation
- saliva
- fluoride source
- plaque control
- diet modification
- these produce more calcium, phosphate and fluoride
does bacteria differ in different areas of the mouth
- yes
- mouth isn’t a homogenous group of bacteria
what does placenta microbiome look like
- a lot lie mothers
- what organisms you have initially in your system has a key role in how you progress
what are the influencing factors of microbiome when born
- human genes
- pregnancy term
- delivery method
- feeding method
- maternal
what are some microbial flora associated with caries
- actinomyces
- bifidobacterium
- lactobacillus
- veillonella
- prevotella
- S. parasanguins
what oral bacteria can predict alzheimers
- spirochaetes
- porphyromonas gingival
what oral bacteria can predict perio
- red complex pathogens = P. gingivalis
- arc heal methanogens
- proteobacteria
what oral bacteria can predict caries
- S. mutans
- lactobacillus
- non-mutans streptococcus
what oral bacteria can predict CVD
- P. gingival
- P. endodontalis
- prevotella intermedia
- prevotella nigrescens
- campylobacter rectus
what oral bacteria can predict CF
- streptococcus oralis
- other strep
what oral bacteria can predict oesophageal cancer
- tannerella forsythia
- p. gingival
- streptococcus pneumonia
what oral bacteria can predict colorectal cancer
- lactobacillus
- rothia
- fusobacterium nuclaetum
what oral bacteria can predict diabetes
- aggregatibacter
- neisseria
- gemella
- porphyromonas
- filifactor
- eubacterium
what oral bacteria can predict pancreatic cancer
- p. gingivalis
- leptotrichia
- aggregatibacter actinomycetemocomitans
what oral bacteria can predict RA
- veillonella
- atopobium
- prevotella
- lactobacillus salivarius
- p. gingivalis
- rotha mucilaginosa
- rothia aerial
