bioenergetics/redox/ox phos Flashcards
coupled rxn requirement
prod of first rxn is substrate for second rxn
three major rxns for interconversion of adenine
kinases, myokinase, nucleoside disphosphate kinase
when energy charge decreases
catabolism increases
when energy charge increases
anabolism increases
oxidation and reduction
LEO says GER
As the redox potential increases, the reaction becomes more exer/endergonic
exergonic
types of ROS detox enzymes 3
Superoxide dismutase, peroxidase, catalase
major components of respiratory chain
NAD-dehydrogenase complex 1 Flavoprotein complex 2 iron sulfer protein--1,2,3 coenzyme q - collect e- from 1,2 cytochrome - heme for cyclic redox
what does cyanide do
bind complex 4, stops electron flow
what does dinitrophenol do
uncouples oxidation from phosphorylation, destroys proton gradient
how does brown fat work
NE -> cascade -> thermogenin, uncouples oxidation from phos, allowing release of heat
example of substrate level phosphorylation
glycolysis
two mechs for transferring reducing compounds from cytosol to mito
malate aspartate tunnel (nadh - nadh)
glycerol po4 shuttle (nadh-fadh)faster and less efficient
