Bioenergetics Flashcards

1
Q

The transfer and utilization of energy in biologic systems

A

Bioenergetics

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2
Q

Measure of change in heat content of the reactants and products

A

Change in Enthalpy

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3
Q

Measure of the change in randomness or disorder of the reactants and products

A

Change in Entropy

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4
Q

Energy available to do work

A

Change in free energy

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5
Q

Net loss of energy? Exergonic or Endergonic?

A

Exergonic

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6
Q

Net gain of energy? Exergonic or Endergonic?

A

Endergonic

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7
Q

Acts as the energy currency of the cell

A

Adenosine Triphosphate

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8
Q

Give the two ways in which your cells produce ATP

A

Oxidative and Substrate Phosphorylation

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9
Q

Greatest quantitative source of high energy phosphate in aerobic organisms

A

Oxidative Phosphorylation

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10
Q

Final common pathway by which electrons from the different fuels of the body flow to oxygen

A

Electron Transport Chain

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11
Q

Electron transport chain is located in the _________, specifically, in the __________

A

Mitochondria

Inner membrane

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12
Q

2 electron carriers used in the ETC

A

NAD+

FAD

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13
Q

NAD derived from

A

Niacin (Vitamin B3)

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14
Q

FADH2 is derived from

A

Riboflavin (Vitamin B2)

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15
Q

Parts of th Mitochondria: Freely permeable to most molecules

A

Outer membrane

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16
Q

Impermeable to most molecules

A

Inner membrane

17
Q

Parts of the Mitochondria: Increase surface area

A

Cristae

18
Q

Part of the mitochondria that contains enzymes, mtDNA, mtRNA, mitochondrial ribosomes

A

Matrix

19
Q

All components in the ETC are fixed to the inner mitochondrial membrane except

A

Coenzyme Q

Cytochrome C

20
Q

Only non-protein component of the ETC

A

Ubiquinone

21
Q

Protons ar pumped to the intermembranous space in 3 complexes?

A

(I, III, IV)

22
Q

Final electron acceptor

A

Oxygen

23
Q

The chemiosmotic hypothesis explains how the free energy generated by the transport of electrons by the electron transport chain is used to produce ATP from ADP+Pi

A

Mitchell Hypothsis

24
Q

When there is lack of oxygen, there is decreased activity of the electron transport chain

A

Tissue hypoxia

25
Q

Compounds that increase the permeability of the inner mitochondrial membrane to protons

A

Uncouplers

26
Q

One of the symptoms of aspirin overdose is

A

Hyperpyrexia

27
Q

Aspirin Overdose: The reason for this is

A

ETC uncoupling with increased body heat production

28
Q

Neonates rely on __________ to produce heat and prevent hypothermia

A

Thermogenin

29
Q

Directly inhibit ATP Synthase (Complex V)

A

ATP Synthase Inhibitors

30
Q

It inhibits oxidative phosphorylation by inhibiting the transporter of ADP into and ATP out of the mitochondrion

A

Atractyloside