biochemsitry 2

Question 1

How does philadpelia chromosome occur?

Answer 1

Translocation of material beween chromsome 9 and chromosome 22

Question 2

How does cystic fibrosis occcur?

Answer 2

Defective CFTR ion channel , resulting in chloride ions accumulating in the cell

Question 3

How is sickle cell disease caused?

Answer 3

The A base is changed to T for the beta chain of haemoglobin, distroting red blood cells

Question 4

What did Griffith do ?

Answer 4

used different strains of bacteria (virulent and non-virulent)and injected into mice

Question 5

What did Griffith find

Answer 5

The mice with the virulent strain were killed , those with the non-virulent strain lived

Question 6

what did griffith prove

Answer 6

that something from the dead cell trasnformed living cell

Question 7

what did avery prove

Answer 7

That it was DNA that caused the transformation

Question 8

What was the live rough strain and heat killed smooth strain treated with in Averys experiment?

Answer 8

DNAse

Question 9

What did Hershey ans Chases experiment show

Answer 9

That the DNA from the T2 enters into the E.Coli enabling it to produce its own coat protein

Question 10

What is a nucleoside

Answer 10

A surgar and a base

Question 11

What is dATP

Answer 11

a nucleotide

Question 12

What bases are purines

Answer 12

A and G

Question 13

What bases are pyrimidines

Answer 13

C and T

Question 14

How many hydrogen bonds between A and T

Answer 14

2

Question 15

How many hydrogen bonds between G and C

Answer 15

3

Question 16

what type of handed helix is DNA

Answer 16

right handed

Question 17

what type of helix is B-DNA

Answer 17

right handed

Question 18

What type of helix is A-DNA

Answer 18

right handed

Question 19

What type of helix is Z-DNA

Answer 19

left handed

Question 20

how is A-DNA formed

Answer 20

formed when DNA is dehydrated

Question 21

How is miRNA transcribed

Answer 21

Transcribed from DNA by RNA pol II

Question 22

What is the polypeptide rule ( little phrase that lecture phrase)

Answer 22

NCaCo

Question 23

How are amino acids joined together

Answer 23

Via a condensation reaction , to join the carboxyl group of one AA to the amino group of the next

Question 24

What group is produced when an amine group reacts with a carboxylic acid

Answer 24

Amid group

Question 25

What is tRNA and what does it do

Answer 25

its an adaptor , connects the amino acids to the nucleic acids

Question 26

Whta are the three words to describe the genetic code

Answer 26

-universal
-Degenerate
-Non overlapping

Question 27

What are the 7 side chains in a protein

Answer 27

R1,R2,R3,R4,R5,R6,R7

Question 28

What side chains in the section of a protein are hydrophobic and hydrophilic

Answer 28

R1,R2,R5 and R6 are hydrophobic
R3,R4 and R7 are polar