Biochemistry option Flashcards

1
Q

What is metabolism

A

the sum of all the reactions in an organism

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are metabolic pathways

A

The control of reactions in sequences and cycles. The product of each step is the reactant for the next.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are metabolites

A

Compounds taking part in metabolism

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is Anabolism: Pathways of synthesis

A

The part of metabolism concerned with building up bigger complex molecules that are higher in energy from small molecules called precursors. (Requires energy) (Hydration reaction)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Examples Anabolism

A

-Proteins from amino acids
-Nucleic acids from nucleotides
-Carbs from photosynthesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is Catabolism: Pathways of Breakdown

A

The metabolic reaction is concerned with the breakdown of larger molecules into smaller molecules (releases energy[ATP]) (hydrolysis)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is Energy Coupling in Metabolism

A

The energy from the catabolic reaction is used to drive anabolic reactions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are Futile cycles

A

Stable complex structures would not exist in cells but be broken down as they form if Anabolic and catabolic reactions did not have different pathways for breakdown and biosynthesis and did not use different enzymes.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What are Trace elements

A

27 out of 100 elements found on Earth are essential components of living things. The majority are in very small amounts.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

96% of all the elements found in cells are?

A

Hydrogen, Oxygen, Carbon, Nitrogen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What Biomolecules

A

The molecules present in living things. Represents an immense diversity of structures.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are Macromolecules

A

Building blocks linked together by covalent bonds,
-Proteins
-Nucleic acids
-Polysaccharides

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Condensation Reaction

A

Form covalent bonds between two molecules releases water

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

In order to form a polymer what does the monomers have to have

A

two functional groups (two linkages, left and right)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is condensation reactions catalyzed by?

A

Polymerase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Hydrolysis reaction

A

Uses water to break molecules, occurs during chemical digestion, and is catalyzed by enzymes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Examples of how biological molecules’ activity depends on structure and shapes?

A

-Structural molecules such as Collegen and cellulose are tough and insoluble.
-Catalytic enzymes depend entirely on the ability to form temporary binding to substrates.
-Chemical messengers such as the hormone insulin must interact specifically with receptor molecules.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What is photosynthesis (ecology)

A

Ability to capture solar energy and use it to synthesize energy rich biomolecules

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What is Cholorophyll?

A

A primary photosynthetic pigment that makes photosynthesis possible

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What is respiration?

A

The release of energy from energy rich molecules like glucose inside cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Outline Respiration

A

1-Glycolosis: Does not use oxygen (anaerobic conditions), only small energy is released from glucose. Enough energy to keep some cells like muscle alive temporarily but enough to keep some bacterial cells alive permanently.

2- In the presence of oxygen (aerobic conditions) the oxidation of glucose is complete and much more energy is released. Which is why most cells need continuous oxygen. The end products are CO2 and water

Aerobic respiration involves a series of coupled redox reaction, where reactants known as cytochromes are successively reduced and re oxide. Oxygen acts as a terminal electron acceptor when reduced to water.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

What kind of reaction is photosynthesis?

A

Anabolic, energy storing [carbon sink]

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

What kind of reaction is Respiration?

A

Catabolic, energy yielding [Carbon sources]

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Why does fats yield more energy than Carbohydrates?

A

Lipids are more reduced then Carbohydrates, thus they can undergo more oxidation and release more energy per unit as a respiratory substrate.

25
Q

What are fat stores in animals called and function?

A

Adipose tissue or blubber, reservoirs of energy

26
Q

Why are Carbohydrates more effective energy storage than lipids?

A

The insolubility of lipids more reactions are needed for breakdown, therefore the energy is released more slowly.

27
Q

Examples of health issues caused by Excess Lipid

A

-Atherosclerosis (fat in blood vessels, high blood pressure)
-Obesity (excessive build up of adipose tissue)

28
Q

Health Issues caused by lipids in respect to Cholesterol, LDL & HDL

A

-Cholesterol is usually the culprit in circulatory diseases.
-Since Cholesterol are insoluble in blood it is transported in lipoproteins (LDL {bad cholesterol} & HDL{good Cholesterol})
-High levels of LDL are associated with increased buildup of cholesterol in the arteries
-High levels of HDL carry cholesterol away from the arteries

29
Q

What are main sources of LDL

A

Saturated fats and trans fats

30
Q

What lower LDL cholesterol?

A

Unsaturated fats

31
Q

Uses of Steroids

A

-Contraceptive pill
-Uses of Testosterone to treat testes and breast cancers
-Used medically to help gain weight after debilitating diseases

32
Q

Abuse of Steroids

A

When Ahmed uses it as a performance enhancing drugs to gain muscle

33
Q

What is in a Trigliceride?

A

Glycerol and 3 fatty acids

34
Q

Draw a glycerol and a fatty acid molecule

A

0_0

35
Q

In what reaction does a glycerol and Fatty acid connect and what linkage?

A

Esterification reaction (condensation reaction) , ester linkage

36
Q

Why are the 3 fatty acids not identical in a triglyciride

A

1-Length of hydrocarbon chain
2-The number and position of carbon to carbon double bond

37
Q

Fatty acid with no double bond

A

saturated

38
Q

Fatty acid with a single double bond

A

mono-unsaturated

39
Q

Fatty acid with several double bonds

A

poly-unsaturated

40
Q

What factors affect the melting point of lipids?

A

1-Length of hydrocarbon chain
2-Degree of Saturation

41
Q

Why do Saturated Fatty acids have a high boiling point?

A

-The carbon single bonds creates a tetrahedral bond angle (109.5)
-As a result the molecules are packed closer together
-Leads to great London Dispersion forces between them
Solid at room temp known as fats, i.e butter, lard etc.

42
Q

Why do unsaturated fatty acids have a low boiling point?

A

-The double bonds creates kink in the chain (120 degrees)
-The molecule is more spread-out
-Weaker intermolecular forces
Liquid at room temp know as oils, i.e corn oil, cod liver oil

43
Q

Outline how to determine the unsaturation of fat using Iodine number

A

-Unsaturated fatty acids can go through addition reactions
-one mole of I2 will react with one mole of carbon carbon double bond
-the iodine number is the amount of iodine that reacts with 100 grams of fat
-The excess iodine can be determined by tritration

44
Q

What is hydrolytic Rancidity

A

Breakdown of fats by hydrolysis reaction from water present in foods.

45
Q

What is the site of reactivity in a hydrolytic rancidity?

A

Ester linkages in triglycerides

46
Q

Conditions for Hydrolytic Rancidity

A

-Presence of Heat
-Enzyme Lipase
-bacteria

47
Q

What is Oxidative Rancidity?

A

When unsaturated fats react with oxygen from the air (auto oxidation)

48
Q

What is the site of reactivity in a oxidative Rancidity?

A

Carbon to carbon double bonds in the unsaturated triglycerides

49
Q

Conditions for Oxidative Rancidity

A

-Light
-Enzyme
-metal ions

50
Q

Product of Hydrolytic Rancidity?

A

Butanoic and octanoic acids

51
Q

Products of Oxidative Rancidity?

A

aldehydes and ketones

52
Q

Structure of Phospholipid

A

Phospholipids are derived from fatty acids and glycerol
-Only 2 fatty acids condensed into a glycerol molecule
-The third OH group is bonded to a phosphate

53
Q

Conditions for hydrolysis of Fats and Phospholipids

A

-Acidic or alkaline conditions with water
-lipases

54
Q

Outline the structure of Steroids

A

-Four fused rings known as a steroidal backbone

55
Q

Function of Lipids

A

-Forms the phospholipid bilayer
-Energy storage
-Thermal insulation (seals)
-Electrical insulation (myelin sheaths)
-Transport of lipid soluble vitamins (A,D,E,K)
-Hormones (testosterone, estrogen)

56
Q

Example of Alpha helix structures

A
  • In Keratin
57
Q

Example of Beta pleated sheets structures

A

Spider silk

58
Q

General Formula of Carbohydrates

A

Cx(H2O)y