Biochemistry - acid/base

Question 1

What concentration is H+ regulated at?

Answer 1

60 millimol H+

Question 2

Does the bicarbonate buffer system does reach equilibrium?

Answer 2

NO

Question 3

What is acidosis?

Answer 3

increased [H+], or a process tending to cause increased [H+]

Question 4

What is alkalosis?

Answer 4

decreased [H+], or a process tending to cause decreased [H+]

Question 5

How would you tell if a disease is repiratory related?

Answer 5

the primary change is in pCO2

Question 6

How would you tell if a disease is metabolicly related?

Answer 6

the primary change is in HCO3-

Question 7

Name 3 respiratory acidosis disorders?

Answer 7

choking
COPD
bronchopneumonia

Question 8

Name 3 respiratory alkalosis disorders?

Answer 8

hysterical overbreathing
mechanical over ventilation
raised intercranial pressure

Question 9

Name 3 metabolic acidosis disorders?

Answer 9

Impaired H secretion
Increases H production or digestion
Loss of HCO3-

Question 10

Name 3 metabolic alkalosis disorders?

Answer 10

Loss of H+ in vomitng
Alkali indegestion
Potassium deficiency

Question 11

What is the normal range of pH?

Answer 11

7.35-7.45

Question 12

What does a low pH indicate?

Answer 12

hypoxia

Question 13

What is the normal range of PO2?

Answer 13

9.3-13.3 kPa

Question 14

What is the normal range of PaCO2?

Answer 14

4.7-6 kPa

Question 15

What does high PaCO2 indicate?

Answer 15

respiratory acidosis

Question 16

What is the normal range for base excess?

Answer 16

-2 to +2 mmol/l

Question 17

What does negative BE indicate?

Answer 17

metabolic acidosis

Question 18

What is uncompensated respiratory acidosis?

Answer 18

Acute Type 2 Respiratory failure

Question 19

What is compensated respiratory acidosis?

Answer 19

Chronic Type 2 Respiratory failure