Biochemistry Flashcards
Where does the Krebs cycle occur
Within mitochondria
What is the Krebs cycle?
Reactions in which acetyl co enzyme A is metabolised carbon dioxide and hydrogen atoms
Can Krebs cycle function in anaerobic conditions?
No
Krebs cycle is the pathway for oxidation of what substances
Carbohydrate fat and some amino acids
Uric acid is formed from the breakdown of what?
Purines
How does serum uric acid levels change in pregnancy?
Levels may fall due to dilution
In what obstetric condition does levels of uric acid rise?
Pre-eclampsia (PET)
Where does reabsorption of uric acid occur
Proximal convoluted tubule
Features of a transudate?
Low protein concentration
Low specific gravity
Low nucleated cell count
Features of an exudate
High protein concentration
Higher specific gravity
Causes of an exudate
Meigs syndrome Malignancy Infection Pulmonary embolus Pancreatitis Tuberculous peritonitis Budd Chiari syndrome
Causes of a transudate
Congestive heart failure Process Hyperproteinaemia Nephrotic syndrome Acute atelectasis Myxoedema Peritoneal dialysis Meigs syndrome End-stage renal disease
Where does 25 hydroxylation of vitamin D occur
In the liver
What happens to vitamin D in the kidney
1 hydroxylation
Effect of renal failure of vitamin D levels
Decreased
