Biochemistry Flashcards

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1
Q

How do enzymes affect chemical reactions?

A

Stabilizes the transition state, thus LOWERING THE ACTIVATION ENERGY of a reaction (DOES NOT stabilize substrate and DOES NOT affect the free energy of a reaction)

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2
Q

Intermolecular Covalent Bonds

A

ex: disulfide bridges; creates structural rigidity

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3
Q

pH dependence of aggregation

A

NEEDS to have pH dependent side chains

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4
Q

Lipase

A

hydrolyzes triacylglycerides

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5
Q

What type of bond connects glucose molecules in glycogen?

A

alpha- 1,4- glycosidic bond

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6
Q

Ribose Structure

A
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7
Q

Fructose

A
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8
Q

Glycogen is very branched due to ___

A

alpha-1,6- glycosidic bonds

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9
Q

How many fused rings in a steroid?

A

4 rings-

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10
Q

Action Potential- NA+ in during what stage

A

Depolarization

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11
Q

Action Potential- K+ ions out

A

repolarization

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12
Q

Maintenance of resting potential relies on Na+/K+ atpase. How many molecules go in/out of cell?

A

For every 2 K+ ions brought into cell, 3 Na+ ions move out of the cell

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13
Q

how do transcription factors regulate the expression of other genes?

A

by binding to the promoter or enhancer of the gene located on the DNA

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14
Q

How do hydrophobic molecules enter the cell

A

SIMPLE DIFFUSION

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15
Q

What does ATP hydrolysis produce

A

ADP + inorganic P

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16
Q

Lipid Rafts

A

cholesterol rich domains w/in the membrane

17
Q

Microtubules

A

bind to chromosomes at the level of the kinetochore and regulate their migration towards the opposite poles of a cell during anaphase

18
Q

Enzymes can change chem rxns through:

A
  1. co localizing substrates
  2. altering local pH
  3. altering substrate shape
19
Q

mRNA levels can

A

increase and decrease

20
Q

mature erythrocytes

A

cells that DO NOT contain DNA

21
Q

Virus & bacteria cultures

A

animal viruses can only infect animal cells, not bacteria. Therefore, animal viruses cannot grow in agar plates w/ bacteria

22
Q

high levels of cirulating glucocorticoids in the blood will cause…

A

increased protein degradation in various tissues, including muscles

23
Q

gluconeogene

A
24
Q

All amino acids (except glycine) are…

A

are all chiral & L-amino acids (except glycine)

25
Q

Glycine the AA is

A

achiral