Biochemical aspect of cancer

Question 0

from connective tissue (e.g. bone, cartilage

Answer 0

Sarcoma

Question 1

arise in epithelial cells

Answer 1

Carcinoma

Question 2

from white blood cells

Answer 2

Leukemia and lymphomas

Question 3

DNA is synthesized and the original DNA duplicated

Answer 3

S phase

Question 4

which the cell divides to produce two daughter cells

Answer 4

M phase

Question 5

the tissue contains cells that proliferate continually to replace those that die or are lost (e.g. the skin, intestine, bone marrow). These cells are known as stem cells

Answer 5

Continually renewing

Question 6

Prone to cancer

Answer 6

Continually renewing cell

Question 7

High on tumor cell, moderate in normal cell

Answer 7

Hexokinase activity

Capacity of glycolysis

Question 8

Arrest of cell cycle

Answer 8

P21

Question 9

Reduction of HMG COA / rate limiting enzyme in cholesterol

Answer 9

Statins

Question 10

Oncogene

Answer 10

Bad

Question 11

Proto oncogene

Answer 11

Good

Question 12

Initiate transduction for DNA replication

- growth factor

Answer 12

Cis oncogene

Question 13

Bind with growth factor

Answer 13

erb B oncogene

Question 14

Need for s phase

Answer 14

DNA polymerase
Cydin
THF

Question 15

Enzyme for DNA replication

Answer 15

Telomerase

Question 16

Continue for DNA replication

Answer 16

Telomers

Question 17

TGF alpha

Answer 17

Platelets

Question 18

TGF beta

Answer 18

Many cells

Question 19

Regulates transcription activity

Answer 19

Retinoblastoma

Question 20

Normal processing od DNA,

Answer 20

Every 200 bp

Question 21

Prevent tetrahydrofolate reductase which is folic acid for DNA replication

Answer 21

Metotrexate