Biochemia: glikoliza Flashcards

1
Q

etap 1: fosforylacja glukozy

A

glukoza + ATP –> glukozo-6-P + ADP
heksokinaza
nieodwracalna

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2
Q

etap 2: izomeryzacja glukozo-6-P

A

glukozo-6-P –> fruktozo-6-P
izomeraza glukozofosforanowa
odwracalna

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3
Q

etap 3: fosforylacja fruktozo-6-P

A

fruktozo-6-P + ATP –> fruktozo-1,6-bisfosforan + ADP
fosfofruktokinaza 1
nieodwracalna

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4
Q

etap 4: rozpad F-1,6-bisP

A

fruktozo-1,6-bisfosforan –> fosfodihydroksyaceton + aldehyd 3-fosfoglicerynowy
aldolaza
odwracalna

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5
Q

etap 5: izomeryzacja fosfodihydroksyacetonu

A

fosfodihydroksyaceton –> aldehyd 3-fosfoglicerynowy
izomeraza fosfotriozy
odwracalna

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6
Q

etap 6: utlenienie aldehydu do kwasu

A

aldehyd-3-fosfoglicerynowy + NAD+ + Pi (nie ATP!) –>
1,3-bisfosfoglicerynian + NADH + H+
dehydrogenaza gliceraldehydo-3-fosforanowa
odwracalna

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7
Q

etap 7: defosforylacja kwasu

A

1,3-bisfosfoglicerynian + ADP –> 3-fosfoglicerynian + ATP
kinaza fosfoglicerynianowa
odwracalna

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8
Q

etap 8: izomeryzacja 3-P-Gc do 2-P-Gc

A

3-fosfoglicerynian –> 2-fosfoglicerynian
mutaza fosfoglicerynianowa
odwracalna

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9
Q

etap 9: dehydratacja 2-P-Gc

A

2-fosfoglicerynian –> fosfoenolopirogronian + H2O
enolaza
odwracalna

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10
Q

etap 10: defosforylacja fosfoenolopirogronianu

A

fosfoenolopirogronian + ADP –> pirogronian + ATP
kinaza pirogronianowa
nieodwracalna

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