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BATTERY REVIEWER - BIOCHEM > BIOCHEM - PRELIM > Flashcards

BIOCHEM - PRELIM Flashcards

1
Q

B-N-glycosidic bond is formed between

A

CYTOSINE AND RIBOSE

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2
Q

Which of the following groups of chemical elements are considered as trace elements?

A

Se, Fe, Cu, Zn

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3
Q

What is the buffer systems in the blood is regulated by the lungs and kidneys?

A

BICARBONATE BUFFER SYSTEM

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4
Q

Which is the true of a replicating segment of eukaryotic DNA that has three origins of replication?

A

THERE WILL BE 6 REPLICATION FORKS

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5
Q

What happens to the Carboxyl group when it donates a proton?

A

NEGATIVELY CHARGED

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6
Q

The chirality of an amino acid results from the fact that it’s a carbon

A

IS BONDED TO FOUR DIFFERENT CHEMICAL GROUPS

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7
Q

Which of the following is TRUE for Fully Protonated form of an Amino Acid?

A

ALL HYDROGEN IONS ARE
ATTACHED (because, hydrogen are protons)

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8
Q

Specific type of covalent bond that links several amino acids together to form peptides or proteins

A

PEPTIDE BOND

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9
Q

Of the 20 standard amino acids, only () is not optically active. The reason is that its side chain ().

A

GLYCINE; is a hydrogen atom

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10
Q

The PO4 end of the DNA is also known as

A

5- PRIME END

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11
Q

The resonance structure that can be drawn for the peptide bond indicate that the peptide bond

A

HAS PARTIAL DOUBLE BOND CHARACTER

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12
Q

Packaging site of cellular secretions:

A

GOLGI

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13
Q

Why is pKa an important property of a compound?

A

IT IS THE ABILITY OF A COMPOUND TO TAKE UP OR DONATE PROTONS INTO SOLUTION

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14
Q

It protects the separated DNA from destruction by nucleases?

A

SSB

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15
Q

When two cysteine molecules dimerize, what happens to the R groups present?

A

THEY REACT WITH EACH OTHER TO PRODUCE A COVALENT DISULFIDE

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16
Q

Which statement is false regarding polypeptides?

A

CAN FORM UNLIMITED NUMBER OF CONFIGURATIONS

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17
Q

Two amino acids of the standard 20 contain sulfur atoms. They are:

A

CYSTEINE and METHIONINE

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18
Q

The chromosome of a bacterium has 22 percent guanine. What is the percent composition of cytosine in this chromosome?

A

22

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19
Q

What class of lipids is usually present in biological membranes?

A

PHOSPHOLIPIDS

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20
Q

What cation serves as a co-factor and is required by the DNA polymerase for its activity?

A

Mg

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21
Q

What forms phosphodiester bonds between fragment of DNA during replication?

A

DNA LIGASE

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22
Q

Unfolding of a protein can be termed as

A

DENATURATION

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23
Q

In condensation process, how many hydrogen atoms are removed?

A

2

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24
Q

Which is TRUE about a single-stranded DNA?

A

THE TOTAL NUMBER OF PURINES IS NOT EQUAL TOTAL NUMBER OF PYRIMIDINES

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25
Q

Amino acids that cannot participate in hydrogen bonding?

A

VALINE

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26
Q

Which of the following is TRUE regarding peptide nomenclature?

A

C-TERMINAL AMINO ACID RESIDUE KEEPS ITS FULL AMINO ACID NAME

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27
Q

Amino acid containing nonpolar, aliphatic R groups

A

Ala, Leu and Gly

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28
Q

The following is made up of nucleotides?

A

COENZYME, CYCLIC-AMP, ATP

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29
Q

It is the amount of heat, per unit mass of liquid, required to raise the temperature by one degree Celsius.

A

SPECIFIC HEAT

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30
Q

What is the amino acids is the most hydrophobic in nature?

A

LEUCINE

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31
Q

Which is true about DNA denaturation?

A

IT OCCURS BY HEATING

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32
Q

If the NH2 group is oriented to the right it is a

A

-D ISOMER

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33
Q

Which is an RNA sequence?

A

GCAUAC

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34
Q

What type of amino acid R group is involved in Electrostatic interaction interactions that contribute to tertiary protein structure?

A

ACIDIC AND BASIC R GROUP

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35
Q

What is the correct classification of polysaccharides?

A

STORAGE AND STRUCTURAL

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36
Q

are conjugated proteins that contain carbohydrates or carbohydrate derivatives in addition to amino acids

A

GLYCOPROTEINS

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37
Q

What is the name of the organic molecule that contains a carboxyl group and amino group?

A

PROTEIN, AMINO ACID

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38
Q

What are places where protein play an important role?

A

ENZYME PRODUCTION

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39
Q

If pK1= 2.34 and pK2 = 9.60, then the isoelectric point pI is?

A

5.97

40
Q

Proteins that are generally insoluble in water and they are involved in structural functions

A

SELENOCYSTEINE

41
Q

What liquids has the highest specific heat?

A

WATER

42
Q

Which statement is mismatched?

A

THE QUARTENARY STRUCTURE IS RELATED TO THE BASIC LINEAR STRUCTURE OF A PROTEIN

43
Q

The two strands of the DNA helix are held together by

A

HYDROGEN BONDS BETWEEN THE BASES

44
Q

What groups of chemicals can be used to denature proteins?

A

ALKALOIDAL REAGENTS, INORGANIC ACIDS, HEAVY METALS

45
Q

Adenine forms a covalent bond with a nucleic sugar at

A

N9

46
Q

A type of protein structure which involves the associations among the peptide chains present in a multimeric protein

A

QUARTERNARY

47
Q

In eukaryotes, histones can bind with DNA because histones have amino acids that are

A

POSITIVELY CHARGED

48
Q

Amino acid with hydroxyl OH group include

A

TYROSINE

49
Q

Which of the following is not the classified form of conjugated proteins?

A

COMPLETE PROTEINS

50
Q

It is a process of modifying the molecular structure of a protein. It involves the breaking of many of the weak linkages, or bonds (e.g., hydrogen bonds), within a protein molecule that are responsible for the highly ordered structure of the protein in its natural (native) state.

A

DENATURATION

51
Q

It provides the OH group to which the DNA polymerase adds the new nucleotide to the growing DNA strand?

A

RNA PRIMER

52
Q

In DNA replication, which enzyme is responsible for the elongation of the new DNA strand?

A

DNA POL III

53
Q

Which was NOT observed in the experiment that showed that DNA replication is semiconservative?

A

The daughter DNAs in the first replication consisted of parent double-stranded DNA (15N strand-15N strand) and a DNA having two new strands (14N strand-14N strand).

54
Q

Defined as the amount of heat needed to turn 1g of a liquid into a vapor.

A

HEAT OF VAPORIZATION

55
Q

Which is a pyrimidine in the DNA?

A

THYMINE

56
Q

What is an example of Fibrous protein?

A

COLLAGEN

57
Q

Zwitterions are?

A

EXIST IN A NEUTRAL pH

58
Q

The monomers of nucleic acids are

A

NUCLEOTIDES

59
Q

What introduces a swivel point in advance of the replication fork to relieve the torsional strain caused by unwinding of the DNA double helix?

A

TOPOISOMERASE

60
Q

A buffer solution is composed of 0.25M acetic acid and 1.20M sodium acetate. What would be the pH of the solution? Select the closest value. (pka of acetic acid is 4.74)

A

5.00

61
Q

This hormone is also called as Anti-Diuretic Hormone and contains 9 amino acid residues

A

VASOPRESSIN

62
Q

Which of the following statements concerning secondary protein is TRUE?

A

IN AN A-HELIX, ALL THE AMINO ACID R GROUPS LIE OUTSIDE THE HELIX

63
Q

Arrange the following in order of molecular complexity (start from the the most complex level):

A

ORGANELLE > SUPRAMOLECULAR COMPLEX > BIOMOLECULES > METABOLITES > INORGANIC PRECURSORS

64
Q

The three-letter abbreviation for the amino acid asparagine is

A

ASN

65
Q

It refers to particularly stable arrangements of amino acid residues in a protein that give rise to recurring patterns?

A

SECONDARY STRUCTURE

66
Q

Which part of the amino acid gives it uniqueness?

A

SIDE CHAIN

67
Q

Polarity compounds are also “water-loving”

A

TRUE

68
Q

Which is NOT true about the synthesis of the lagging strand?

A

THE DIRECTION OF SYNTHESIS IS TOWARD THE REPLICATION FORK

69
Q

Amino acid are ampholytes because they can function as either a(n)

A

ACID OR BASE

70
Q

Which is NOT true about prokaryote and eukaryote DNA replication?

A

EUKARYOTES REQUIRE RNA PRIMERS BUT PROKARYOTES DO NOT

71
Q

What amino acid has indole ring in its side chain?

A

TRYPTOPHAN

72
Q

The acid component of the buffer:

A

ADDS MORE H+ TO THE SOLUTION, RELEASE H+

73
Q

The smallest amino acid is

A

GLYCINE

74
Q

Which pair of amino acid absorbs the UV light at 280nm?

A

TRP AND TYR

75
Q

Which of the following statements concerning secondary protein is TRUE?

A

Both a-helix and b-pleated sheet structures can be present in the same protein.

76
Q

Which base pair is not found in DNA?

A

ADENINE- GUANINE

77
Q

Which statement is not true about the side chains of amino acids?

A

ARE ALWAYS CHARGED AND PRESENT IN ALL AMINO ACID

78
Q

Peptide bond is a?

A

COVALENT BOND

79
Q

Protein folding is?

A

RESULTS IN HYDROPHILIC EXTERIOR

80
Q

Which of the following is correct with respect to the amino acid composition of proteins?

A

Proteins with different functions usually differ significantly in their amino acid composition

81
Q

A branch of science that describes the molecular nature of life processes.

A

BIOCHEMISTRY

82
Q

Amino acids are building blocks of

A

PROTEIN AND POLYPEPTIDES

83
Q

The peptide bond in proteins is

A

PLANAR, USUALLY FOUND IN TRANS CONFORMATION

84
Q

The site of formation of new DNA is called

A

REPLICATION FORK

85
Q

Derivatives of purines and pyrimidines that have a sugar linked to a ring nitrogen

A

NUCLEOSIDES

86
Q

What amino acids is the uncharged derivative of an acidic amino acid?

A

GLUTAMINE

87
Q

Specific type of covalent bond that links several monosaccharides together to form carbohydrates.

A

GLYCOSIDIC BOND

88
Q

This is an important small organic biochemical compound that supplies energy to numerous chemical reactions.

A

ATP

89
Q

Which is NOT required in DNA synthesis

A

dUTP

90
Q

Ten base pairs per complete turn of the helix is a characteristic of

A

B-DNA

91
Q

The alpha helix is an example of which of the following structural properties of proteins?

A

SECONDARY

92
Q

Command center of the cell:

A

NUCLEUS

93
Q

Which is a wrong nomenclature?

A

DEOXYTHYMINE

94
Q

Which is NOT true regarding the sugar in DNA?

A

LACKS O AT C1-PRIME

95
Q

What happens if the pH of the solution is greater than the pKa of the amino acid?

A

AMINO ACID WILL BE DEPROTONATED

96
Q

Arrange the following in order of molecular complexity (start from the simplest level):

A

METABOLITES > MONOSACCHARIDES > RIBOSOMAL COMPLEX > CELL

97
Q

Which statement is FALSE?

A

THE TWO COILED STRANDS OF DNA RUN IN PARALLEL DIRECTIONS

BATTERY REVIEWER - BIOCHEM (3 decks)

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