Biochem- Lipoprotein

Question 1

List the four distinct groups of lipoprotein.

Answer 1

Chylomicron
VLDL - very low density lipoprotein
HDL - high density lipoprotein
LDL- low density lipoprotein

Question 2

List the levels of LDL Cholesterol.

Answer 2

Optimal - <100
Near to above optimal - 100-129
Borderline high - 130- 159
High - 160-189
Very high - 190 and above.

Question 3

List the levels for HDL Cholesterol.

Answer 3

Increase risk of major CHD — < 40
Protection against heart disease — 60 and above.

Question 4

List the characteristics of chylomicron.

Answer 4

Synthesized in the small intestine
98% lipids
Mobilized and transport dietary lipids
Large sized
Density <96

Question 5

List the characteristics of VLDL

Answer 5

Synthesized in the liver
90% lipids
Transport endogenous triglycerides
APO B- 100
APO C-II
APO E - librates free fatty acids that are taken up by the adipose tissue and muscle.

Question 6

List the characteristics of LDL

Answer 6

Synthesized from IDL (Intermediate Density Lipoprotein)
78% lipids
Transfers cholesterol to tissues
Half life of 2 days

Question 7

List the characteristics of HDL

Answer 7

Synthesized in the liver and small intestine
48% lipids
Reverse cholesterol transfer
Reservoir for apoproteins
APO A- activates LCAT.
APO C - activates LPL