BIO 224A ENDO NOTES

Question 1

Hydrophilic hormone

Answer 1

• On cell surface
• Polar bonds ( -NH, -OH)
• water soluble

Question 2

Hydrophilic hormone receptor type

Answer 2

AA based

Question 3

AA based

Answer 3

1. Cell surface receptor( Transmembrane)
2. Requires 2nd messenger ( Ions channels, enzymes, signal amplifications, free transport)

Question 4

Hydrophobic hormone

Answer 4

• Inside the cell
• Non-polar bonds ( -CH)
• (Lipids/fats, lipophilic)

Question 5

Hydrophobic hormone receptor type

Answer 5

Steroid hormone

Question 6

Steroid hormones

Answer 6

1. receptors ( Cytosolic)
2. hormone-receptor complex ( Bind HRE( DNA sequence)
3. Affect protein synthesis ( as as “transcription factor”)
   ( DOES NOT REQUIRE SECOND MESSENGER BECAUSE IT CAN CROSS CELL MEMBRANE AND BIND TO INTRACELL)

Question 7

Hormone released in anterior pituitary (5)

Answer 7

thyroid stimi hormone (TSH)
Follicle stimi hormone ( FSH)
Lutenizing hormone ( LH)
Growth horomone (GH)
Prolactin ( PRL)

Question 8

GhRH ( growth hormones-releasing hormone)

Answer 8

relase human growth hormone ( hGH)

Question 9

TRH ( thyroid releasing hormo)

Answer 9

release TSH

Question 10

CRH ( Corticotropin releasing hormo)

Answer 10

release adrenocorticotopic hormo ( AcTH)

Question 11

GnRH ( Gonadotropin releasing hormo)

Answer 11

Produce FSH and LH

Question 12

PRL ( Prolcatin releasing hormone)

Answer 12

release prolactin

Question 13

hormone released in posterior pituitary

Answer 13

Oxytocin and ADH

Question 14

ADH

Answer 14

Produced in hypo, stored and released

Question 15

Oxytocin

Answer 15

produced in hypo
secreted in Posterior Pituitary