bio Flashcards
what is a conjugated protein
contains non protein group
has prosthetic group - Fe
prosthetic group attached by covalent bonds
which non essential hormones are made in the medulla
adrenaline and noradrenaline
role of adrenaline
increases heart rate
increases blood glucose conc
converts glycogen in to glucose
role of noradrenaline
works with adrenaline
increases heart rate
widens pupils
widens air passage in the lungs
narrowing of blood vessels in non essential organs - increases BP
which vital hormones are produced in the adrenal cortex
gluco cort icoids
mineralo cort icoids
androgens
role of glucocorticoids
- cortisol regulates metabolism buy controlling how the body converts fats, proteins and cards into energy
- helps regulate BP and cardiovascular function in response to stress
- corticosterone works with cortisol to regulate immune system and suppress inflammatory reactions
- controlled by hypothalamus
role of mineralocorticoids
- aldosterone helps control blood pressure by maintaining the balance between salt and water conc in the blood and body fluids
- release mediated by signals triggered by kidney
role of androgens
- small amounts of male and female sex hormones
- impact small
- oestrogen, testosterone
structure of adrenal gland
outer layer = adrenal cortex
inner layer = medulla
steroid hormones
lipid soluble
- can pass through lipid component of cell membrane and bind to steroid hormone receptors
- form hormone receptor complex
- acts as a transcription factor which facilitates or inhibits the transcription of specific gene - oestrogen
non steroid hormones
hydrophilic - cannot pass directly through the cell membrane
- they bind to specific receptors on cell surface membrane on the target cell
- triggers cascade reaction mediated by chemicals called second messengers - adrenaline
action of adrenaline
- adrenaline is hydrophilic so cannot pass directly through the membrane
- adrenaline attaches to receptor on cell surface membrane
- forms adrenaline receptor complex
- when adrenaline binds to receptor - enzyme adenlylyl cyclase is activated
- adenlylyl cyclase converts ATP to cyclic AMP.
- this activates enzyme protein kinase to convert glycogen into glucose.
- example of a cascade effect as at each stage the number of molecules involved increases
role of Kuffer cells
destroy bacteria in the blood travelling through the liver
role of sinusoid
sinusoid are small channels surrounded by liver cells - hepatocytes and they carry the blood form the sources to the central vein
the blood fro the hepatic vein and artery and mixed and this increased the o2 content of the blood from the hepatic portal vein - supplying the hepatocytes with enough o2
functions of the liver
- bile synthesis - aids fat digestion
- gluconeogenesis
- storage of iron, copper and vitamins
- location of the orthinine cycle
- regulation of glycogen storage
- detoxification