BILIARY DISORDERS Flashcards
- inflammation of the gallbladder which can be __ or __
Cholecystitis
acute or chronic.
___ is the cause of more than 90% of cases of ____
Calculous cholecystitis (gall stones)
acute cholecystitis.
___ describes acute gallbladder inflammation in the absence of obstruction by _____.
- Acalculous cholecystitis
gallstones
- _____ of the gallbladder develops if the gallbladder becomes filled with purulent fluid.
empyema
CALCULOUS CHOLECYSTITIS
- a gallbladder stone ___ bile outflow.
- ___ of bile occurs in approximately 50% of cases.
- The organisms involved are generally enteric and include ,,_
obstructs
Secondary infection
Escherichia coli, Klebsiella species, and
Streptococcus.
- acute gallbladder inflammation in the absence of obstruction by gallstones.
ACALCULOUS CHOLECYSTITIS
- hard deposits (gallstones, calculi) that may form in the gallbladder.
- gallstones usually form from the solid constituents of bile.
CHOLELITHIASIS
(____ in color)
- Caused by conditions that produces __
- The risk is increased in patients with cirrhosis, hemolysis, and infections of the biliary tract.
- cannot be dissolved and must be removed ___.
- Pigment stones
dark brown or black
too much bilirubin
surgically
(_____ in color)
– caused by ___. (decreased bile acid synthesis and increased cholesterol synthesis in the liver
- resulting in bile supersaturated with cholesterol, which precipitates out of the bile to form stones.
- Cholesterol stones
yellow-green
imbalances bile composition
RISK FACTORS OF CHOLELITHIASIS:
- ____ (leads to rapid development of gallstones and high risk of symptomatic disease)
- Treatment with high-dose estrogen (eg, in prostate cancer)
- ___ – a small increase in the risk of gallstones
- Ileal resection or disease
- Cystic fibrosis
- Diabetes mellitus
Rapid weight loss
Low-dose estrogen therapy
Clinical Manifestations
- Pain and Biliary Colic
- excruciating ___ pain that radiates to the ___ or ___
- usually associated with nausea and vomiting.
- noticeable several hours after a heavy meal.
- In some patients, the pain is ___ rather than colicky - ____
- frequently accompanied by marked pruritus of the skin. - Changes in Urine and Stool Color
– ______ urine (bile excretion by the kidney) and
- _____ feces (absence of bile) - Vitamin Deficiency
- vitamins _____ deficiency. No absorption.
RUQ
back or right shoulder.
constant
Jaundice
dark-colored urine
grayish or clay-colored feces
A, D, E, and K
- the diagnostic procedure of choice because it is rapid and accurate with 90% accuracy.
- most accurate if the patient fasts overnight so that the gallbladder is distended
Ultrasonography
____
- used successfully in the diagnosis of acute cholecystitis or blockage of a bile duct.
a radioactive agent is administered IV which is taken up by the ___ and excreted rapidly through the biliary tract.
- The biliary tract is then scanned, and images of the gallbladder and biliary tract are obtained.
- often used when ultrasonography is not conclusive, such as in ____.
Radionuclide Imaging or Cholescintigraphy
hepatocytes
acalculous cholecystitis
- used if ultrasound equipment is not available or if the ultrasound results are inconclusive.
- an iodine-containing contrast agent that is excreted by the liver and concentrated in the gallbladder is given 10 to 12 hours before the x-ray study.
- If gallstones are present, they appear as ___ on the x-ray image.
Oral Cholecystography
shadows
– permits direct visualization of structures.
- examines the hepatobiliary system via a side-viewing flexible fiberoptic endoscope inserted through the esophagus to the descending duodenum.
- __ & ___ are used during ERCP to evaluate the presence and location of ductal stones.
- The patient is ___ for several hours before the procedure.
- Moderate is used.
- During ERCP, the nurse monitors ___, administers medications, and positions the patient.
- After the procedure, the nurse monitors the patient’s condition, observing vital signs and assessing for signs of ____
Endoscopic Retrograde Cholangiopancreatography
Fluoroscopy and multiple x-rays
NPO
Sedation
IV fluids
perforation or infection.
- involves the injection of dye directly into the biliary tract.
- reserved for patients whom an _____ due to previous surgery.
- The fluoroscopy table is tilted and the patient is repositioned to allow x-rays to be taken in multiple projections.
- It is useful for:
1. distinguishing jaundice caused by liver disease (____) from that caused by
biliary obstruction,
2. investigating the GI symptoms of a patient whose gallbladder has been removed,
3. locating stones within the bile ducts, and
4. diagnosing cancer involving the biliary system.
Percutaneous Transhepatic Cholangiography (PTC)
ERCP may be unsafe
hepatocellular jaundice
Pharmacologic Therapy
- acts by inhibiting the synthesis and secretion of cholesterol.
- can reduce the size of existing stones, dissolve small stones, and prevent new stones from forming.
- ____ of therapy is required in many patients to dissolve stones.
- Ursodeoxycholic acid (ursodiol) and chenodeoxycholic acid (chenodiol)
Six to 12 months
Nonsurgical Removal of Gallstones
- infusion of a __ into the gallbladder.
- used for patients who may not be candidates for __
Dissolving Gallstones
solvent (mono-octanoin or methyl tertiary butyl ether [MTBE])
laparoscopic cholecystectomy.
____
- a catheter and instrument with a basket attached are threaded through the T-tube tract or fistula formed at the time of T-tube insertion.
- the __ is used to retrieve and remove the stones lodged in the common bile duct.
Stone Removal by Instrumentation
basket
___
- Stones are fragmented by means of laser pulse technology.
- A ___ is directed under fluoroscopic guidance with the use of devices that can distinguish between stones and tissue.
- The laser pulse produces rapid expansion and disintegration of plasma on the stone surface, resulting in a __
- used percutaneously with a basket or balloon catheter system or by direct visualization through an ___.
Intracorporeal Lithotripsy
laser pulse
mechanical shock wave.
endoscope
Surgical Management
a. Preoperative Measures
- __ may be given if the prothrombin level is low.
- Provide IV glucose with protein supplements to __
Vitamin K
aid wound healing.
- __ nonsurgical fragmentation of gallstones.
- uses repeated shock waves directed at the gallstones in the gallbladder or common bile duct to fragment the stones.
- The waves are transmitted to the body through a fluid-filled bag or by immersing the patient in a water bath.
Extracorporeal Shock Wave Lithotripsy (lithotripsy or ESWL)