Bias Flashcards

1
Q

A systematic error that causes the effect estimate to deviate from the truth

A

Bias

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2
Q

What are the three types of biases?

A

Selection bias, Information bias, and Confounding

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3
Q

an error resulting in systematic differences in characteristics between participants enrolled
in a study and potential participants who do not (or who are not asked to participate)

A

Selection bias

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4
Q

Both experimental and observational studies are subject to ________ and ______ biases

A

Selection and Information

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5
Q

Error in the measurement of exposure or outcome data that results in different levels of
accuracy for information collected from the comparison groups

A

Information bias

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6
Q

Selection bias is related to _____ validity

A

External

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7
Q

Information bias is related to ______ validity

A

Internal

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8
Q

Erroneous classification of the individual into a category other than that which he or she
should have been assigned

A

Misclassification

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9
Q

a bias resulting from the distortion of the exposure – outcome association by a third factor, i.e. a mixing of effects of the confounder and the exposure on the outcome

A

Confounding

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10
Q

Confounder ____ causes (can be a proxy) the outcome

A

independently

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11
Q

Confounder is associated with the ______

A

exposure

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12
Q

The confounder is ___________ across the levels of the exposure but does not result from the exposure

A

unevenly distributed

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13
Q

Observational studies particularly prone to ______

A

Confounders

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14
Q

What are the ways to prevent confounding?

A

Randomization, Restriction, and Matching

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15
Q

Theoretically balances confounders between arms of study

A

Randomization

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16
Q

Restricts study population to one level of potential confounder

A

Restriction

17
Q

Match exposed and unexposed on potential confounding factor

A

Matching

18
Q

What are the ways to assess and control confounding?

A

Stratification and Statistical modeling

19
Q

Stratify the data by the ________ and examine the crude and stratum-specific estimates

A

potential confounder

20
Q

If the stratum-specific estimates are similar (homogeneity of effect), pool the estimates with what test?

A

Mantel-Haenszel OR

21
Q

If the ORMH differs from the ORcrude by more than X% (%-change criterion an arbitrary
value set a priori), then report ___________

A

the pooled estimate

22
Q

Examine effect estimate from model with the exposure (may contain other variables)

A

Reduced

23
Q

Examine effect estimate from model that differs by only the potentially confounding variable

A

Full

24
Q

If the adjusted estimate differs from the reduced estimate by more than X% (%-change
criterion an arbitrary value set a priori), then report___

A

the adjusted estimate