BG testing Flashcards

1
Q

oral glucose tolerance tests are mainly used for diagnosis of …. and may be required when….

A

impaired glucose tolerance
may be required when less severe symptoms and BG conc does not establish or exclude diabetes e.g impaired fasting glycaemia

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2
Q

OGTT are also used to establish the presence of…

A

gestational diabetes

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3
Q

what does an OGTT involve

A
  • measuring BG conc after fasting, then 2 hours after drinking a standard anhydrous glucose drink
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4
Q

glycated haemoglobin forms when…

A

RBC are exposed to glucose in plasma

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5
Q

HbA1c test reflects the average plasma glucose over the previous …….. months and provides good indicator of glycemic control

A

2-3 months

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6
Q

advantages of HbA1c over OGTT

A
  • provides good indication of glycaemia control
  • can be performed at any time of day and does not require special prep like fasting
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7
Q

HbA1c is used to monitor glycaemic control in both T1D and T2D, but is only used as for diagnosis for…

A

T2D

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8
Q

do not use HbA1c as diagnosis for

A
  • suspected T1D
  • children
  • pregnancy
  • women up to 2 months PP
  • symptoms of diabetes for <2 months
  • high diabetes risk and acutely ill
  • treatment with meds that may cause hyperglycaemia (e.g. diuretics)
  • acute pancreatic damage
  • end stage CKD
  • HIV
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9
Q

HBA1c used for diagnosis should being interpreted with caution in pt with…

A
  • abnormal HB
  • anaemia
  • altered red cell lifespan
  • recent blood transfusion
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10
Q

how often should HbA1c be measured in pt with T1D

A
  • every 3-6 months
  • more freq if BG control is thought to be changing rapidly
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11
Q

how often should HbA1c be measured in pt with T2D

A

monitored every 3-6 months until HbA1c and medication are stable when monitoring can be reduced to every 6 months

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12
Q

HbA1c monitoring is invalid for pt with disturbed erythrocyte turnover or for pt with a lack of, or abnormal Hb . what can you use instead

A

quality-controlled plasma glucose profiles
total glycated Hb estimation (if there is abnormal hb)
fructosamine estimation

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13
Q

Lab measurement of fructosamine concentration measures….

A

the glycates fraction of all plasma proteins over the previous 14-21 days but is a less accurate measure of glycaemic control than HbA1c

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