anterior pituitary hormones

Question 1

this is an analogue of corticotropin (ACTH) that is used to test adrenocorticol function

Answer 1

tetracosactide

Question 2

what is tetracosactide used for

Answer 2

diagnosis of adrenocortical insufficiency

Question 3

how does the tetracoside test of adrenocortical insufficiency work

Answer 3

if plasma cortisol concentration doesn’t increase after administration of tetracosactide, this indicated adrenal insufficiency

Question 4

name the gonadotropins used in the treatment of infertility. in women with proven HYPOpitiutarism or who have not responded to clomifene (anti oestrogen) or in super ovulation treatment for assisted conception (e.g. in IVF)

(2)

Answer 4

FSH follicle stimulating hormone
LH leutinising hormone

Question 5

what is GH use to treat

Answer 5

deficiency of the hormone in children and in adults

Question 6

name the GH drug used for deficiency in children and adults

Answer 6

Growth hormone of human origin (HGH; somatotrophin) has been replaced by recombinant growth hormone of human sequence; somatropin is licensed for use in adults and children, and somatrogon (a long-acting form) is licensed for growth hormone deficiency in children.

Question 7

name the human insulin like growth factor-I that is licensed to treat growth failure in children with severe primary insulin like growth factor-I deficiency

Answer 7

Mecasermin

Question 8

Gonadorelin analogues are indicated in the following 4

Answer 8

endometriosis
infertility
breast cancer
prostate cancer