Beyond Xanax Meds (Midterm) Flashcards
Sx of serotonin syndrome
- dilated pupils
- N/D
- restlessness
- confusion
- tachy
- inc BP
- sweating
- loss of muscle coordination, twitching
- muscle rigidity
Preferred SSRIs
- Sertraline (Zoloft)
- Fluoxetine (Prozac)
- Escitalopram (Lexapro)
Dosing range for Sertraline (Zoloft)
25mg - 250mg
Indications for Sertraline (Zoloft)
- Anxiety
- Depression
- OCD
- Irritability
When do you see results of Sertraline (Zoloft)
3 wks (2 if tweaking)
Sertraline (Zoloft) S/Es
- GI disturbance
- Reflux
- Somnolence
- Libido
Dosing range for Fluoxetine (Prozac)
10mg - 80mg
Indications for Fluoxetine (Prozac)
- Anxiety
- Depression
- OCD
- Motivation
When do you see results of Fluoxetine (Prozac)
4 wks (2-3 if tweaking)
Fluoxetine (Prozac) S/Es
- Anorexia
- Activation (take in AM)
- Libido
Dosing range for Escitalopram (Lexapro)
5mg - 40mg
Indications for Escitalopram (Lexapro)
- Anxiety
- Depression
When do you see results of Escitalopram (Lexapro)
3 wks (2 if tweaking)
Of the 3 preferred SSRIs, which one is the most activating/serotonergic?
Escitalopram (Lexapro)
Escitalopram (Lexapro) S/Es
- Activating
- Weight gain
Prior to initiation of SSRI Citalopram (Celexa), what do you need to ensure you’ve asked your patient? Why?
If they have/had any cardiac issues - concern for QT prolongation
What are the 3 preferred SNRIs
- Duloxetine (Cymbalta)
- Desvenlafaxine (Pristiq)
- Venlafaxine (Effexor)
What is the dosing range for Duloxetine (Cymbalta)
20mg - 120mg
Indications for Duloxetine (Cymbalta)
- Pain
- Anxiety
- Depression
*NOT irritability
When do you see results of Duloxetine (Cymbalta)
4 wks (2-3 if tweaking)
Duloxetine (Cymbalta) S/Es
- GI disturbance
- Somnolence
- Libido
- W/D syndrome
What is the dosing range for Desvenlafaxine (Pristiq)
25mg - 100mg
Indications for Desvenlafaxine (Pristiq)
- Anxiety
- Depression
- Energy
When do you see results of Desvenlafaxine (Pristiq)
4 wks (3 if tweaking)
Desvenlafaxine (Pristiq) S/Es
- Libido
- W/D syndrome - much more gentle though
Which of the 3 preferred SNRIs is well tolerated, has no metabolism in the liver, and lower risk of DDIs?
Desvenlafaxine (Pristiq)
What is the dosing range for Venlafaxine (Effexor)
37.5mg - 300mg
Indications for Venlafaxine (Effexor)
- Anxiety
- Depression
- Energy
When do you see results of Venlafaxine (Effexor)
3-4 wks (2 if tweaking)
Venlafaxine (Effexor) S/Es
- WICKED W/D SYNDROME
- Libido
- Last resort!
How many days is needed for initiation and b/w ramping doses of SSRIs
3-7 days
How many days is needed for initiating and b/w ramping doses of SNRIs
14 days (modulating 2 NTs)
What are some adjunct medications
- Buspar
- Wellbutrin
- Abilify
- Lithium
- Lamictal
Buspar indication, S/E, dosing
- Anti anxiety
- S/E: Dizziness
- Inc to 10mg BID
Wellbutrin indication and dosing
- Motivation, sexual side effects, smoking
- SR 75mg - 400mg, XL 150mg - 450mg
Wellbutrin SEs
- Lowers seizure threshold
- Inc anxiety
Abilify indications and dosing
- Super charger for mood lability/emotional reactivity
- 2mg - (30mg) - typically do not go above 5mg
What labs do you need to obtain when a patient is taking Abilify?
Alc, Lipids after 6 months - then 1 x yr
Abilify S/Es
- Sedation
- Weight gain
Lithium indications
- SI (esp. in adolescents)
- Depression
What is the dosing range for Lithium
ER 300mg - 450mg (600mg)
What do you need if you are prescribing >600mg of Lithium
Labs - lithium level, TSH, CMP
Lamictal indications
emotional reactivity
What is the dosing range for Lamictal
25mg - 200mg (400mg) - anything >200mg is not effective
What labs do you need to get if a patient is prescribed Lamictal
A1c, Lipids after 6 months - then 1 x yr
Lamictal S/Es
- SJS
- Weight gain
What are the non stimulants used for ADHD
- Strattera
- Guanfacine/Intuniv
What are the stimulant options for ADHD
- Adderall
- Vyvanse
- Focalin
- Concerta
- Methylphenidate