ADHD meds (French) (Midterm) Flashcards

1
Q

Pharmacologic treatment of ADHD in children has been reported to:
A. Increase the risk of accidents in adolescents
B. Reduce the risk of substance abuse in adolescents
C. Increase the risk of cancer in adulthood
D. Reduce the risk of CV events

A

B. Reduce the risk of substance abuse in adolescents

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2
Q
An appropriate first-line treatment for a 4y/o boy in prekindergarten with recently diagnosed ADHD would be: 
A. Behavioral classroom intervention
B. Methlphenidate
C. Amphetamine
D. Atomoxetine
A

A. Behavioral classroom intervention

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3
Q
Which of the following is the drug of choice for treatment of ADHD symptoms in most school-age children and adults?
A. Long-acting stimulant
B. Atomoxetine
C. Alpha-2 agonist
D. SSRI
A

A. Long-acting stimulant

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4
Q

A 9y/o boy with ADHD has not responded to maximum doses of methylphenidate. His mother asks if he should take an amphetamine instead. You could tell her that:
A. Amphetamines are more effective than methlyphenidate
B. Patients who do not respond to methylphenidate generally do not respond to an amphetamine
C. Patients who do not respond to methylphenidate may respond to an amphetamine and vice versa
D. Amphetamines are not approved by the FDA for use in school-age children

A

C. Patients who do not respond to methylphenidate may respond to an amphetamine and vice versa

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5
Q
Immediate-release methylphenidate has a duration of action of: 
A. 1-3hrs
B. 3-5hrs
C. 6-8hrs
D. 8-10hrs
A

B. 3-5hrs

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6
Q
Jornay PM (methylphenidate) is taken at night to: 
A. Improve efficacy in the evening
B. Improve efficacy in the morning
C. Reduce adverse effects in the morning
D. All of the above
A

B. Improve efficacy in the morning

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7
Q

Long-acting methlyphenidate formulations that can be used in patients who are unable to swallow tablets or capsules include:
A. Capsules that can be opened and sprinkled on food
B. An oral suspension
C. A transdermal patch
D. All of the above

A

D. All of the above

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8
Q

The transdermal methylphenidate patch:
A. Should be applied 2hrs before an effect is needed
B. Was approved based on data in children and adolescents
C. Can be removed before 9hrs if a shorter duration of effect is desired
D. All of the above

A

D. All of the above

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9
Q

The main problem with short-acting stimulants is that:
A. They are less effective than intermediate- or long-acting formulations
B. They have a higher incidence of adverse effects than longer acting drugs
C. They generally require administration of a second dose during school hours
D. All of the above

A

C. They generally require administration of a second dose during school hours

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10
Q
Which of the following is a common short-term adverse effects of stimulants?
A. Loss of appetite
B. Bradycardia
C. Somnolence
D. All of the above
A

A. Loss of appetite

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11
Q

Which of the following is an advantage of atomoxetine over methlyphenidate?
A. It has been shown to be more effective for treatment of ADHD symptoms in adults
B. It does not cause growth delay
C. It is not a controlled substance
D. All of the above

A

C. It is not a controlled substance

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12
Q
A 10y/o boy with ADHD who did not respond adequately to stimulant mono therapy has been taking ER clonidine as an adjunct to amphetamine, but he often feels lightheaded upon standing. The most likely cause of this complaint is: 
A. Hypotension
B. Anxiety
C. Vertigo
D. Munchausen syndrome
A

A. Hypotension

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13
Q
In a large cohort study, methylphenidate use during the first trimester of pregnancy was associated with a small increase in the risk of: 
A. Spina bifida
B. Cardiac malformations
C. Cleft lip 
D. All of the above
A

B. Cardiac malformations

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14
Q

A concerned father going through a difficult divorce brings his 14y/o son to your office and asks for your help in dealing with his behavior. His school performance has deteriorated, and his teachers say that he does not pay attention in class. In addition, his parents have noticed that he has developed facial grimaces, especially when he is upset. His father asks if a stimulant could be helpful. You would have to tell him that:
A. Stimulants can themselves cause tics or make them worse
B. Stimulants are highly effective in treating tics
C. Stimulants are not approved by the FDA for use in adolescents
D. Stimulants have no adverse effects and are always worth trying in these situations

A

A. Stimulants can themselves cause tics or make them worse

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15
Q
Atomoxetine (Strattera) is: 
A. a stimulant
B. A controlled substance
C. A SSRI
D. A Selective NRI
A

D. A Selective NRI

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16
Q
The main problem in using extended-release alpha 2- agonists to treat ADHD has been: 
A. Somnolence
B. HTN
C. Rash 
D. Nausea
A

A. Somnolence