Beth - Week 5 - Exam 2 Flashcards
what is the normal processes for the brain?
- constant blood flow
- blood flow removes waste
- cerebral autoregulation
what occurs in the event of a stroke?
ischemia → hypoxia and hypoglycemia (lack of O2 and nutrients) → infarct (death of cell)
T/F we want to save the penumbra
YAAASSS
what is the penumbra?
the area that is surrounding the dead core that is minimally being perfused
the ability to save the penumbra depends on three things. what are they?
- timely return of adequate circulation
- volume of toxins released by dead cells
- degree of cerebral edema
TEST: what are the main risk factors for stroke?
- atherosclerosis
- a. fib
- diabetes
- HTN
- heart disease
- hyperlipidemia
- oral contraceptives
- obesity
- prior stroke
- sedentary lifestyle
- smoking
what are the other risk factors for stroke?
- age
- gender - male
- familial tendency
- African American
- TIA
- vasospasm
what is the warning sign of a stroke?
TIA - transient ischemic attack
- **temporary stroke symptoms
- **must be taken seriously
what are the sxs of a TIA?
confused, slurred speech, CT scan → blood in brain → seems normal in ER → red flag
T/F: a key point of TIA is that they are a precursor to thrombotic strokes
TRUE
how long can TIA s/sx last?
a few minutes to < 24hr
___% of stokes are preventable
80
stroke is the ____ leading cause of death in the US
5th
what are the types of stroke?
- ischemic (87%) and hemorrhagic
what are the two types of ischemic strokes?
thrombotic and embolic
what is usually the cause of hemorrhagic strokes?
HTN
TEST: what are the clinical manifestations of a right hemisphere stroke?
- left hemiplegia
- spatial-perceptual defects
- denial of deficits
- neglect lt. side
- euphoric/smile
- impaired sense of humor
- poor judgment
- defects in lt. visual field (Hemianopsia)
- impulsive
T/F there is a better outcome for a right hemisphere stroke
TRUE
what are the clinical manifestations of a left hemisphere stroke?
- right hemiplegia
- neglect rt side
- defects in rt visual field
- expressive/receptive aphasia or global aphasia (broca)
- unable to discriminate words/letters (wernicke)
- worry/depression/emotional lability
- quick anger/frustration
- intellectual impairment (cognitive)
- slow/cautious
how to acute ischemic strokes (thrombotic) occur?
vessel loses elasticity (hardens) → narrowing of the vessels lumen
**NOT d/t a bleed
what is the #1 risk factor for acute ischemic stroke (thrombotic)?
atherosclerosis
how do sxs appear for acute ischemic stroke (thrombotic)?
- symptoms sudden or often during sleep or in morning (HTN spikes)
- OR a gradual process → collateral circulation plays a role
how do acute ischemic strokes (embolic) occur?
- traveling blood clot
- tends to lodge in small vessels or bifurcations
how to the sxs present for an acute ischemic stroke (embolic)?
sudden onset of symptoms - could follow by a clearing for hours to few days
TEST: where does the AIS (embolic) occur?
middle cerebral artery - major game changer - now capable to do treatment endovascularly - pull out clot/plaque
TEST: what is the number 1 cause of AIS embolic? and what meds can we use as tx?
A. Fib → control A. fib and put on blood thinner
how does a hemorrhagic stroke occur?
integrity of the vessel is interrupted
- bleeding into tissue or subarachnoid space
for a hemorrhagic stroke, _____ immediately shows bleed
CT
what are the three examples of hemorrhagic stroke?
- Intracerebral bleed
- subarachnoid hemorrhage
- AVM
T/F hemorrhagic stroke are less common
TRUE
what should you do to prevent hemorrhagic stroke?
control HTN
what is the most often occluded artery in a stroke?
the middle cerebral artery (MCA)
what is the largest branch of the internal carotids?
the middle cerebral artery
the MCA provides blood to where?
- the frontal lobe
- lateral surface of temporal and parietal lobes
- motor and sensory
- face, throat, hand, arm
- if dominant - speech
A patient arrives in the ER with new symptoms of hemiparesis, sensory loss, gaze deficit and aphasia. what are these symptoms of?
consistent with MCA stroke → time is essence, call code stroke.
the brain requires ____ of total body’s O2 and ___ of cardiac output
20; 10
the arterial artery of brain: where does the anterior circulation originate from?
the carotids
the arterial artery of the brain: where does the posterior circulation originate from?
the vertebral
where do the anterior circulation and the posterior circulation merge?
the circle of willis
what are the 4 large vessel strokes?
- carotid, vertebral (COW, ACA, MCA, PCA)
- ischemic stroke (occlusion d/t thrombus)
- ICH (hemorrhage at junctions and vessel turns)
- SAH (aneurysms form at vessel junctions and turns)