beta2 agonists Flashcards
name the most common beta 2 agonist
salbutamol
name another
terbutaline
what are they?
short acting
an alternative usually third line treatment
what type is it
salmetrol
long acting
three things used to treat and which lne
asthma -1st line - long acting- 3rd line but always with inhaled corticosteroids
COPD - 1st line, long acting, second line
hyperkalaemia
why is long acting given with Inhaled cotercosteriods
without was associated with increased risk of asthma deaths
what therapy is given via nebuliser?
oxygen in asthma
air on copd
side effects
b2 activation - fight or flight tachycardia tremor anxiety palpitations glycogenlyosis therefore may increase serum glucose reduced K+
interactions
beta blockers may reduce effectiveness of thes dugs
consideration of on combined therapy or nebulised
K+ level
MOA
b2 receptors on SM of bronchi
stimulating these receptors causes relacation to relieve breathelnessness
stimulates Na K ATPase pump causes K to shift from extracellular to intracellular compartment therefore good for hyperkal treatment
caution in who?
cvd pts with tachycardia
may initiate angina or arrthymias