Beta Oxidation

Question 1

4 steps of beta oxidation

Answer 1

1- oxidation
2 - hydration
3 - oxidation
4 - thiolysis

Question 2

Step 1

Answer 2

Oxidation by FADH forms a double bond btw the the alpha and beta carbons of fatty acyl CoA
Alkane to alkene
FAD to FADH2
Enzyme used - acyl coA dehydrogenase

Question 3

Step 2

Answer 3

Water is added across the double bond (hydration) to give an alcohol at the beta carbon
Alkene to alcohol
Uses H2O
Enzyme: enoyl CoA hydratase

Question 4

Step 3 of beta oxidation

Answer 4

Oxidation of the alcohol by NAD+
alcohol to ketone
Uses enzyme B-hydroxyacyl CoA dehydrogenase

Question 5

Step 4

Answer 5

Lysis (thiolysis) of bond btw alpha and beta carbons
Addition of CoASH
Enzyme: acetyltransferase
acyl-Co-A acyl

Question 6

Thiolysis

Answer 6

A thiol analogue of a hydrolysis

Question 7

What are the products of one round of beta oxidation

Answer 7

An Acetyl CoA
A FADH2
And NADH + H+
The fatty acyl CoA mlc gets shortened by 2 carbons