benign uterine and ovarian diseases Flashcards
1
Q
leiomyomas
A
- aka fibroids
- most common pelvic tumor in women
- benign
- come from SMC of myometrium
2
Q
locations of leiomyomas
A
- intramural myoma- most common
- subserosal
- submucosal
- cervical
- if stemmed= pedunculated
3
Q
si/sx of leiomyomas
A
- most are small and asymptomatic
- heavy or prolonged menstrual bleeding
- pelvic pain/pressure
- urinary frequency, difficulty emptying bladder
- LBP
- dyspareunia
- reproductive dysfunction
4
Q
PE findings and diagnosis for leiomyomas
A
- enlarged and irregular uterus
- +/- tenderness
- dx with transvaginal US
5
Q
treatment for leiomyomas
A
- based on type of fibroid and severity of sx
- menopause causes fibroids to shrink
- watchful waiting
- medical mgmt
- surgery* mainstay of tx
6
Q
medical management for leiomyoma
A
- NSAIDs- only for dysmenorrhea
- OCPs or IUDs
- GnRH- leuprolide (leupron) to induce menopause state
7
Q
surgical options for leiomyoma
A
- hysterectomy
- myomectomy- cut out fibroid layer, must be submucosal fibroid
- endometrial ablation- burn tissue to stop BF
- uterine artery embolization
8
Q
indications for leiomyoma surgery
A
- abnormal uterine bleeding
- bulk related sx
- infertility
- recurrent miscarriages
9
Q
adenomyosis
A
- ectopic endometrial tissue within myometrium
- causes hypertrophy and hyperplasia
- boggy uterus
- not well differentiated from surrounding tissue, difficult to excise
- more common in parous females
10
Q
adenomyoma
A
- adenomyosis confined to one area
- resembles fibrouds
11
Q
si/sx of adenomyosis
A
- heavy menstrual bleeding*
- dysmenorrhea*
- chronic pelvic pain
- diffusely enlarged uterus- globular
12
Q
dx of adenomyosis
A
- pathology after hysterectomy
- transvag US or MRI may be helpful in assessment
13
Q
key words on imaging for adenomyosis
A
- asymmetric thickening of myometrium
- linear striations
- loss of clear endomyometrial border
- increased myometrial heterogeneity
14
Q
treatment for adenomyosis
A
- hysterectomy*
- +/- uterine artery embolization
- OCPs and IUDs may decrease bleeding and pain
- GnRH analogs and aromatase inhibitors
15
Q
endometriosis
A
- abnormal endometrial mucosa implanted in locations other than uterine cavity
- estrogen dependent
16
Q
risk factors for endometriosis
A
- family hx
- nulliparity
- early age menarche
- short menstrual cycles
- long duration of menstrual flow
- heavy menstrual bleeding
17
Q
common sites of endometriosis
A
- ovaries- most common
- uterus
- posterior cul-de-sac
- broad ligament/ uterosacral ligament
- rectosigmoid colon
- bladder
18
Q
si/sx of endometriosis
A
- severity of sx doesnt always correlate to extent of disease
- asymptomatic
- dysmenorrhea
- heavy or irregular bleeding
- pelvic pain*
- lower abd pain/ LBP
- dyspareunia
19
Q
PE findings for endometriosis
A
- lateral displacement of cervix
- localized tenderness in posterior cul-de-sac
- palpable tender nodule in posterior cul-de-sac
- pain with mvmt of uterus
- severe abd pain- ruptured endometrioma
20
Q
complications of endometriosis
A
- endometrioma “chocolate cysts”
- adhesion formation
- pain
- anatomic distortion
- infertility
- implantation onto nearby structures
21
Q
diagnosis of endometriosis
A
- laparoscopy with biopsy*
- blue black or powder burned appearance
- transvag US to r/o other pathology
22
Q
medical management of endometriosis
A
- 95% responsive to medical mgmt but half have sx relapse in 5 yrs
- combined OCPs
- GnHR analogs
- danazol- androgenic steroid
23
Q
surgical mangament of endometriosis
A
- hysterectomy +/- oophorectomy= definitive
- laparoscopic uterine nerve ablation
- drainage and laparoscopic cystectomy
- laparoscopy and surgical endometrial implant ablation- high rate reoperation