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Oral Pathology Heavy > Benign Tumors > Flashcards

Benign Tumors Flashcards

1
Q

Describe a squamous papilloma in terms of color, size, sessile vs pedunculated

A

White or pink, less than 5mm, sessile most often

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2
Q

What tissues are contained in a squamous papilloma lesion?

A

SSE that is keratinized or parakeratinized. There is a core of vascular connective tissue

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3
Q

Describe the clinical features of verruca vulgaris, color, type of lesion, sessile vs. pedunculated, solitary or multiple

A

White but occasionally pink, nodule or papule, sessile or pedunculated, multiple

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4
Q

Where do most cases of verruca vulgaris occur?

A

In the anterior part of the mouth

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5
Q

Describe the histologic appearance of verruca vulgaris

A

Multiple projections composed of keratinized SSE. Long rete ridges with kilobytes in the outer spinous layer

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6
Q

What types of HPV are associated with verruca vulgaris?

A

2, 4, 6, 40

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7
Q

Describe condyloma acuminatum in terms of color, texture, sessile vs pedunculated, solitary or multiple

A

White or pink, warty, sessile, multiple nodules

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8
Q

How does the size of a condyloma acuminatum lesion compare to papilloma?

A

Tend to be larger

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9
Q

Condyloma acuminatum represents what other disease?

A

A sexually transmitted one

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10
Q

What tissue and cells are seen in condyloma acuminatum?

A

Acanthotic SSE and koilocytes. The broad projections have a core of vascular connective tissue

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11
Q

What do lesions look like in Heck’s disease?

A

Pale plaques or papule which tend to cluster

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12
Q

Where do lesions most often occur in Heck’s disease?

A

Labial or buccal mucosa

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13
Q

Keratoacanthoma is often mistaken for? What does it arise from?

A

Cancer, arises from pilosebaceous units

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14
Q

Describe the lesions in keratoacanthoma

A

Well-defined, umbilicated nodules up to 1.5cm in diameter

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15
Q

Describe the growth pattern of keratoacanthoma

A

Grows rapidly, reaching full size in 6 weeks and then regresses

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16
Q

What are the most common sites for a melanotic macule?

A

Vermilion of the lower lip, buccal mucosa, gingiva, and palate

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17
Q

Are melanotic macules solitary or in clusters?

A

Solitary most of the time

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18
Q

What causes lentigo?

A

Hyperplasia of melanocytes

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19
Q

Which type of lentigo is unrelated to sun exposure?

A

Lentigo simplex

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20
Q

What is lentigo senile?

A

Benign condition that usually occurs on the face, sun-exposed areas

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21
Q

What is lentigo maligna?

A

Melanoma in situ, the purely radial growth phase. Grows for up to 15 years

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22
Q

Describe the epithelium in lentigo maligna

A

Atrophic with loss of rate ridges and hyper plastic melanocytes are atypical

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23
Q

Most nevomelanocytic nevi occur in men or women?

A

Women

24
Q

What are the most common sites for nevomelanocytic nevi?

A

Hard palate, buccal mucosa, lip, gingiva

25
Q

Most oral nevi are of which type?

A

Intramucosal

26
Q

What is the 2nd most common type of melanocytic nevus?

A

Blue nevus

27
Q

Where do most blue nevi occur?

A

On the palate

28
Q

Junctional nevi have nevus cells in what layers?

A

bulging down from the basal layer

29
Q

In compound nevi and intramucosal nevi, where are the nevus cells?

A

In compound they extend from the junction into the lamina propria. Intramucosal, the cells are confined to the lamina propria

30
Q

Melanoacanthosis most often occurs in who?

A

African-American females

31
Q

How does melanoacanthosis present itself?

A

Dark brown macules or patches in the buccal mucosa. They can be more intensely pigmented centrally

32
Q

How large can melanoacanthosis lesions get?

A

Several centimeters

33
Q

What tissues and cells are seen in melanoacanthosis?

A

Acanthotic SSE with spongiosis.
Dendritic melanocytes scattered throughout tissue
Eosinophils are seen in the epithelium and lamina propr.

34
Q

Verruciform xanthoma presents as?

A

A solitary, red or white, sessile lesion

35
Q

What causes verruciform xanthoma?

A

Usually trauma

36
Q

Who gets verruciform xanthoma and where do they occur?

A

Middle aged or elder people on the gingiva or alveolar ridge

37
Q

What are xanthoma cells?

A

Lipid filled macrophages

38
Q

Xanthomas are seen in what two illnesses?

A

Diabetes mellitus and familial disturbances in lipid metabolism

39
Q

Is a lipoma encapsulated?

A

Yes

40
Q

What can cause a herniated buccal fat pad?

A

herniation of the buccal fat pad through the buccinator muscle

41
Q

How do you distinguish a buccal fat pad from a lipoma?

A

Skeletal muscle fibers within the adipose tissue

42
Q

When do oral lymphangiomas appear

A

At birth or in the first 2 years of life

43
Q

Where do oral lymphangiomas appear?

A

On the anterior dorsal surface of the tongue

44
Q

What is pathagnomic for oral lymphangioma?

A

Irregular, grey or pink fluid filled papillations on the anterior dorsal tongue

45
Q

The papillations of oral lymphangioma are lined by?

A

Endothelium

46
Q

What is cystic hygroma?

A

Large, multicystic lymphangioma of the neck

47
Q

What symptoms can cystic hygroma cause?

A

Dysphagia and dyspnea

48
Q

Are leiomyomas freely movable or fixed?

A

Freely movable

49
Q

Are leiomyomas encapsulated? What cells are they composed of?

A

Encapsulated. Composed of spindle cells with cigar shaped nuclei

50
Q

How do you definitely diagnosis leiomyoma?

A

IHC identification of antigenic actin filaments

51
Q

What do most oral leiomyomas arise from?

A

Vascular smooth muscle

52
Q

Are traumatic neuromas freely movable or attached?

A

Attached

53
Q

What symptoms may a patient experience with a traumatic neuroma?

A

Pain or tenderness

54
Q

In what case is a neurofibroma free movable?

A

If it arises within the perineurium

55
Q

Can a neurofibroma be encapsulated?

A

Yes, if the proliferation occurs within the perineurium otherwise it blends into the surrounding CT

56
Q

Neurofibromas are composed mostly of what kind of cell?

A

Schwann cells

Oral Pathology Heavy (7 decks)

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