Benign and premalignant tumours Flashcards

1
Q

characteristics of Seborrhoeic Keratoses

A

*Benign, but commonly referred

*Warty growths, “stuck on appearance”

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2
Q

treatment of Seborrhoeic Keratoses

A

*Generally left untreated, but if troublesome
–Cryotherapy
–Curettage

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3
Q

whats the Sign of Leser-Trelat

A

*Abrupt onset of widespread seborrhoeic keratosis, particularly in a younger individual

*SKs remain benign but may indicate underlying solid organ malignancy–GI adenocarcinoma

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4
Q

whats a Dermatofibroma

characteristics x2

A

Benign fibrous nodule

*Firm nodule, tethered to skin but mobile over fat. Pale pink/brown. Often paler in centre.
*Dimple sign positive

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5
Q

whats a lipoma

A

Benign tumour consisting of fat cells

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6
Q

when is a lipoma concerning- possibly malignant

A

If tender

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7
Q

whats an angioma

risk of it

treatment

A

Overgrowth of blood vessels in the skin due to proliferating endothelial cell

–Pregnancy & liver disease

–Excision or laser

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8
Q

whats a Pyogenic Granuloma

treatment

A

Rapidly enlarging red/raw growth, often at a site of trauma.

–Removed by curettage & cautery

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9
Q

whats Bowen’s Disease

A

*aka Intraepidermal squamous cell carcinoma

–Full thickness dysplasia, entirely contained within the epidermis, no metastatic potential

*Irregular, scaly erythematous plaque

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10
Q

treatment of bowens

A

*Cryotherapy
*Curettage
*Photodynamic therapy
*Imiquimod

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11
Q

whats Actinic Keratoses

A

*Rough scaly patches on sun damaged skin

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12
Q

treatment for Actinic Keratoses x4

A

–Cryotherapy
–Curettage
-DiclofenacGel
–Imiquimod

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13
Q

whats melanoma in situ

treatment

A

*Melanoma cells entirely confined to epidermis
*No metastatic potential

*Treated with excision

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14
Q

whats Lentigo Maligna

treatment

A

*Type of melanoma in situ
*Usually facial

Sun Protection

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15
Q

characteristics of basal cell carcinoma x4

A

*Slow growing
*Locally invasive
*Rarely metastasise
*Nodular

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16
Q

treatment for basal cell carcinomas x3

A

*Excision is gold standard
*Curettage in some circumstances
*Imiquimodif superficial

17
Q

what drug is used in advanced and malignant basal cell carcinomas

A

Vismodegib

18
Q

characteristics of squamous cell carcinomas x4

A

Faster growing
tender
scaly/crusted or fleshy growths
canulcerate

19
Q

Treatment of squamous cell carcimona

A

*Excision
*+/-Radiotherapy

20
Q

ABCDE rule of melanoma

A

*Asymmetry
*Border- undefined
*Colour- multiple
*Diameter- over 7mm
*Evolution

21
Q

treatment of melanoma

A

surgery

Immunotherapy –metastasis or adjuvent therapy

22
Q

where do cutaneous metastasis come from

A

Most commonly breast, colon and lung