Benign and Malignant Neoplasms Flashcards

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1
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Basal Cell Carcinoma

  • Ulcerated
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1
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Mycosis Fungoides

  • Tumors
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2
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Spontaneous Keloids

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2
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Actinic Keratoses

  • Pre cancerous skin lesion to squamous cell carcinoma
  • Dry, hard, rough scaly papules in sun-exposed areas of skin
  • Scraping will not cause bleeding
  • Cryotherapy is treatment of choice
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3
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Classic Kaposi Sarcoma

  • Diagnose through biopsy
  • Treated with radiation and chemotherapy
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4
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Blue Nevus

  • Papule or nodule, firm, dark-blue to gray-black. Usually very small.
  • Appear in children and young adults.
  • Asymptomatic
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4
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Metastatic Melanoma

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5
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Squamous Cell Carcinoma- Highly differentiated

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6
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Spreading pigmented Actinic Keratosis (SPAK)

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6
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HIV/AIDS Associated Kaposi Sarcoma

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6
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HIV/ADIS Associated Kaposi Sarcoma

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6
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Dermal Melanocytic Nevomalanocytic Nevi

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7
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Adult T-Cell leukemia/Lymphoma

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7
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Mycosis Fungoides

  • Leonine Facies
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8
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Mycosis Fungoides

  • Poikilodermatous lesions
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9
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Amelanotic Melanoma

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10
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Squamous Cell Carcinoma

  • Well differentiated
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10
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Basal Cell Carcinoma

  • Nodular Type
  • Malignant epithelial tumor that does NOT metastisize
  • MOST COMMON cancer in humans
  • Caused by UVR, some pts. with multiple lesions have inherited mutation
  • Locally invasive
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10
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Basal Cell Carcinoma

  • Ulcerated
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12
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Nevus Spilus

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12
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Basal Cell Carcinoma

  • Nodular Type
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12
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Basal Cell Carcinoma

  • Sclerosing, nodular, and ulcerating
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12
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Superficial Spreading Melanoma

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14
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Mongolian Spot

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15
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Superficial Basal Cell Carcinoma

  • Pigmented
  • Similar to nodular form, but with pigmentation
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16
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Cellular Blue Nevus

  • Bluish-black nodules
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16
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Mycosis Fungoides

  • Lymphadenopathy and abnormal lymphs in blood correlate with internal organ involvement
  • Treatment determined by stage
  • May include PUVA, interferon, electron beam therapy and others
  • REFER
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18
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Pyogenic Granuloma

  • Typical colar of thickened stratum corneum at base on palms and soles
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19
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Hypertrophic Scar

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20
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Nodular Melanoma

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21
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Squamous Cell Carcinoma

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22
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Seborrheic Keratosis (solitary)

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22
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Squamous Cell Carcinoma

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22
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Metastatic Melanoma

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23
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Multiple Hypertrophic Scars

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24
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Basal Cell Carcinoma

  • Ulcerated
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24
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Superficial Spreading Melanoma

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25
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Superficial Spreading Melanoma

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26
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Dermatofibroma

  • Dimple sign: Dimpling of the lesion seen when pinched between two fingers
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27
Q
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Mycosis Fungoides

  • Patches/plaques stage
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28
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Pigmented Spitz Nevus

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29
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Pyogenic Granuloma

  • Benign vascular lesion that evolves quickly over a period of weeks
  • Red papule or nodule that is prone to ulceration and bleeding
  • Treatment is excision with electrodessication
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29
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Squamous Cell Carcinoma

  • In pt. with peripheral neuropathy due to leprosy
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29
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Nodular Melanoma

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31
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Actinic Keratoses

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32
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Superficial Basal Cell Carcinoma, Invasive

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33
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Keratoacanthoma

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34
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Blue Nevus

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34
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Solitary Lipoma

  • Lower arm
35
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Basal Cell Carcinoma

  • Ulcerated
37
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Actinic Keratosis

39
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Nevus of Ota

  • Macule
  • Distirbuted around the trigeminal nerve, including mucous memb and sclera
  • Not hereditary, but most common in Asians.
  • Will not fade or disappear
39
Q
A

Sebaceous Cyst (Epidermoid Cyst)

  • Forms in dermis and is lined with epithelial cells that produce keratin, filling cyst with thick, yellow-white material
  • Most commonly on face and back
  • Treatment is excision
39
Q
A

Keloid

  • Arose following a burn
39
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Superficial Basal Cell Carcinoma

40
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Multiple Nevomelanocytic Nevi

-Shoulder

42
Q
A

Halo Nevomelanocytic Nevi

44
Q
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Spitz Nevus

  • Pink, dome-shaped nodule, dome shaped, hairless
  • Appear in children and adults under 40.
  • Develop abruptly, get biopsy to confirm benign
45
Q
A

Halo Nevomelanocytic Nevi

47
Q
A

Seborrheic Keratosis

49
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A

Squamous Cell Carcinoma

50
Q
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Superficial Spreading Melanoma

52
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Junctional Nevomelanocytic Nevi

  • Macule, tan to black, round with smooth borders, always < 1cm
  • Usually appear in childhood
  • Often progress to compound, then to dermal
53
Q
A

Seborrheic Keratoses (multiple)

53
Q
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Mycosis Fungoides

  • MOST COMMON cutaneous lymphoma
  • Involves T cells and occurs in older adults
  • Classified as patch, plaque or tumor stage
  • Scaly and erythematous
  • Multiple biopsies often necessary
54
Q
A

Superficial Spreading Melanoma

  • Treatment: REFER!
  • Excision with wide margins
  • TNM staging of cancer
56
Q
A

Junctional Nevomelanocytic Nevi

57
Q
A

Melanoma

57
Q
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Metastatic Melanoma

59
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A

Squamous Cell Carcinoma

60
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A

Nodular Melanoma

62
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Basal Cell Carcinoma

  • Nodular Type
64
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A

Actinic Keratoses

  • Prevention through the use of hats an sunscreens
65
Q
A

Nevus of Ota

65
Q
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Melanoma

  • Malignancy of melanocytes that occurs in the skin, eyes, ears, and GI tract, oral, and genital mucosa
  • One of the most dangerous tumors - has ability to metastisize to any organ
  • LEADING CAUSE of death due to skin disease
66
Q
A

Acral Lentiginous Melanoma

67
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Squamous Cell Carcinoma in Situ (SCCIS)

68
Q
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Mycosis Fungoides

  • Tumor Stage
69
Q
A

Dermal Melanocytic Nevomalanocytic Nevi

70
Q
A

Melanoma

  • Risk Factors:
  • Dysplastic nevus
  • Congenital nevus
  • Large # of benign moles
  • Family Hx
  • Red hair and freckling, and white race
  • Inability to tan
  • Chronic tanning (>10 times annually)
71
Q
A

Keratoacanthoma

  • Associated with squamous cell carcinoma
  • Thin scale with an erythematous nodule as the base
  • There are several stages of this
73
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A

Basal Cell Carcinoma

  • Nodular Type
74
Q
A

Classic Kaposi Sarcoma

76
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A

Nevus Spilus

  • Dark brown pigmented macule
  • Size of area varies, but can be large
  • Junctional and compund nevi scattered in defined area of increased melanocytes
77
Q
A

Syringomas

  • Benign tumors of the eccrine glands most commonly located around the eyes
  • Small, flesh to light colored papules, usually mutliple and near both eyes.
  • No treatment necessary, but may be removed for cosmetic purposes
78
Q
A

Classic Kaposi Sarcoma

  • HHV Type 8
  • Can be localized or generalized, and occur in tages of patches, plaques, and nodules
  • Can evolve into nodules or tumors - If systemic involvement occurs, it is mainly in GI tract
  • Most common in HIV infected males
79
Q
A

Amelanotic Melanoma

81
Q
A

Cutaneous Horn: Hypertrophic Actinic Keratosis

83
Q
A

Dermatofibroma

84
Q
A

Seborrheic Keratosis

  • MOST COMMON benign cutaneous neoplasm
  • Absolutely no malignant potential
  • Begin to appear during middle age, then grow and increase with age
  • No treatment required
85
Q
A

Metastatic Melanoma

85
Q
A

Mycosis Fungoides

  • Poikilodermatous lesions
86
Q
A

Compound Nevomalanocytic Nevi

88
Q
A

Basal Cell Carcinoma

  • Sclerosing Type
90
Q
A

Mongolian Spot

  • Macule, gray-blue, usually in lumbrosacral area
  • Congenital, seen in Asians and Native Americans.
  • May fade or disappear
  • Refer for cosmetic laser surgery
92
Q
A

Seborrheic Keratosis

93
Q
A

Basal Cell Carcinoma

  • Ulcerated
  • Pearly, firm, bumpy border, but with ulcer in middle
94
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Metastatic Melanoma

95
Q
A

Dermatofibroma

  • Button-like dermal nodule
  • Usually solitary lesion on lower legs
  • May develop in response to trauma
  • Usually will have dimple sign
  • No treatment required
96
Q
A

Basal Cell Carcinoma

  • Sclerosing Type
  • Has waxy, firm, flat to slightly raised lesion that appears “scar-like”
97
Q
A

Nodular Melanoma

98
Q
A

Dermal Melanocytic Nevomalanocytic Nevi

99
Q
A

Halo Nevomelanocytic Nevi

  • Halo of depigmented skin around a junctional or compound nevus
  • Will regress leaving white spot, which will slowly repigment.
  • May also occur around melanoma so presence does not insure that nevus is benign
101
Q
A

Keloids

  • Abnormally large scar that extends beyond margins of injury.
  • Firm, tuberous papule or nodule that often continues to grow slowly
  • Treatment difficult as it is not highly effective.
102
Q
A

Squamous Cell Carcinoma - Undiferentiated

103
Q
A

Compound Nevomalanocytic Nevi

  • Papule or nodule, light to black but usually dark brown
  • Smooth or cobblestone, defined borders, always < 1 cm.
  • Either firm or soft
  • Appear in childhood
  • If excised, pathology should always be obtained
105
Q
A

Keratoacanthoma

106
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A

Amelanotic Melanoma

108
Q
A

Superficial Spreading Melanoma

109
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A

Junctional Nevomelanocytic Nevi

110
Q
A

Superficial Basal Cell Carcinoma

  • Pigmented
111
Q
A

Junctional Nevomelanocytic Nevi

112
Q
A

Lipoma

  • Common benign faty tumors
  • Freely mobile, soft mass under the skin
  • No treatment typically necessary
114
Q
A

Amelanotic Melanoma

115
Q
A

Squamous Cell Carcinoma

  • Slow-growing malignant tumor of squamous epithelium that can metastisize to other areas
  • Caused by UVR or by HPV infection
  • Small lesions treated with cryosurgery
  • Large lesions excised
116
Q
A

Adult T-Cell leukemia/Lymphoma

  • Many types
  • Extranodal proliferations of T or B cells, but eventually lymph nodes and internal organs can become involved

-

117
Q
A

Acral Lentiginous Melanoma

118
Q
A

Melanoma - In Situ

119
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Superficial Spreading Melanoma

120
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A

Squamous Cell Carcinoma

  • Advanced, well differentiated
121
Q
A

Basal Cell Carcinoma

  • Nodular Type
122
Q
A

Acral Lentiginous Melanoma