Bengin Liver Disease Flashcards
List types of benign liver disease
Common solid lesion is
Hemangioma
Common cystic lesion
Hydatid cyst
Diagnosis of liver cell adenoma
- Physical exam is usually unrevealing
- tumor markers are normal
- CT usually demonstrates a well-circumscribed
heterogenous mass that shows early
enhancement during the arterial phase. - MRI scans, have specifc imaging characteristics,
including a well-demarcated heterogenous mass
containing fat or hemorrhage
Two major risks of Adenoma
The two major risks are rupture (with potentially life-
threatening intraperitoneal hemorrhage) and malignant transformation.
Patients with asymptomatic adenoma who take OCPs can be watched for regression after?
stopping the OCPs
2nd common benign tumor of the liver
Focal Nodular Hyperplasia
FNH mass is characterized by
a central fbrous scar with radiating septa, although no central scar is seen in about 15% of cases
Diagnosis of FNH
- Physical examination is usually unrevealing
- CT and MRI (homogeneous mass with a central scar that rapidly enhances during the arterial phase of contrast administration.
- Rupture, bleeding, and infarction are exceedingly
rare, and malignant degeneration of FNH has never
been reported - Patients with persistent symptomatic FNH or an
enlarging mass need to be considered for resection.
Symptoms of hemangioma
- Most are asymptomatic and incidentally found on
imaging studies. - Symptoms cause vague upper abdominal
- Spontaneous rupture of liver hemangiomas is
exceedingly rare. An associated syndrome of
thrombocytopenia and consumptive coagulopathy known as Kasabach-Merritt syndrome is rare but well described
Diagnosis of hemangioma
- CT and MRI (peripheral nodular enhancement pattern is seen.
- Labeled red blood cell scans are an accurate test but are rarely necessary if high-quality CT and MRI are available
Treatment of hemangioma
An asymptomatic (observation
Sugical enucleation indicated in
- Symptomatic(resection
- Rupture
- change in size
- development of the Kasabach-Merritt syndrome
- In rare cases of diagnostic uncertainty