BENADRYL Flashcards
CLASSIFICATION
ANTIHISTAMINE
GENERIC NAME?
DIPHENHYDRAMINE
MECHANISM OF ACTION
NONSPECIFIC COMPETITIVE H1/H2 ANTOAGONIST BLOCKS HISTAMINE RELEASE SUPPRESSES CENTRAL CHOLINERGIC ACTIVITY AND INHIBITS REUPTAKE AND STORAGE OF DOPAMINE LEADING TO PROLONGED ACTION OF DOPAMINE AND REDUCTION OF BRONCHOCONSTRICTION VASODILATION INCREASED VASCULAR PERMEABILITY
ONSET OF ACTION
10-15 IV 15-30 PO
PEAK EFFECTS
1-4 HOURS
DURATION OF EFFECTS
6-8 HOURS
HALF LIFE
1-4 HOURS
INDICATIONS FIELD USE
ALLERGIC REACTION
ANAPHYLAXIS DYSTONIC REACTION
CCONTRAINDICATIONS
HYPERSENSITIVITY
SIDE EFFECTS ADVERSE REACTIONS
SEDATION DRIES BRONCHIAL SECREATIONS BLURRED VISION HA PALPITATIONS DIZZINESS DROWSINESS FATIGUE UPHORIA HYPOTENSION
DOSE ADULT
25 TO 50MG IV,IO,IM,PO
DOSE PEDI
1MG/KG IV,IO,IM,PO MAX DOSE 50 MG
PRECAUTIONS
CAUTIONS WITH PATIENTS WITH SEVERE LIVER DISEASE AND ACUTE ASTHMA
DRUG -DRUG
POTENTIATES SEDATIVE EFFECTS OF ETOH, BENZOS CNS DEPRESSANTS AND MAOI’S