amyl nitrate

Question 0

MECHANISM OF ACTION

Answer 0

SHORT ACTING VASODILATOR AND SMC RELAXANT THAT OXIDIZES HEMOGLOBIN TO BECOME METHEMOGLOBIN WHICH FORMS A NON-TOXIC COMPLEX WITH THE CYANIDE ION TO FORM CYANOMETHEMOGLOBIN WHICH AND BE ENZYMATICALLY DEGRADED

Question 1

DRUG CLASSIFICATION

Answer 1

ANTIDOTE/NITRATE VASODILATOR

Question 2

ONSET OF ACTION

Answer 2

10-30 SEC

Question 3

PEAK EFFECTS

Answer 3

30 SEC

Question 4

DURATION OF EFFECT

Answer 4

3-5 MIN

Question 5

HALF LIFE

Answer 5

N/A

Question 6

INDICATIONS/ FIELD USE

Answer 6

CYANIDE POISONING

Question 7

CONTRAINDICATIONS

Answer 7

NONE

Question 8

SIDE EFFECTS ADVERSE REACTIONS

Answer 8

HA, DIZZINESS, WEAKNESS, FLUSHING, COLD SWEATS, TACHYCARDIA, SYMCOPE, ORTHOSTATIC HYPOTENSION, N+V

Question 9

DOSE ADULT

Answer 9

0.3ML AMPULE CRUSHED INHALED OVER 15-30 SEC Q 1 MIN UNTIL SODIUM NITRATE INFUSION IS ABALIABLE.

Question 10

DOSE PEDI 0.3ML AMPULE CRUSHED INHALED OVER 15- 30 SEC Q 1 MIN UNTIL SODIUM NITRATE INFUSION IS AVALABLE

Answer 10

SAME AS ADULT

Question 11

PRCAUTIONS

Answer 11

MAY BE A MED OF ABUSE SHOULD BE STORED IN SECURE PLACE WITH NARCOTICS SMELLS LIKE DIRTY SWEATY SOCKS
ENSURE PATIENT IS SITTING PRIOR TO ADMINISTRATION HYPOTENSION AND SYNCOPE MAY BE SUDDEN

Question 12

DRUG TO TRUG INTERACTIONS

Answer 12

HYPOTNSION POTENTIATED BY ANDIHYPERTENSIVES, B BLOCKERS AND CERTAIN ANTIEMETICS (PHENOTHIAZINES)