behcet's disease Flashcards
1
Q
epidemiology
A
high prevalence in Japan, Middle East, and Turkey
2
Q
What is the HLA connection
A
HLA-B51 allele
**think B for behcet’s
3
Q
clinical features
A
recurrent oral ulcerations (pathos stomatitis), recurrent genital ulceration, ocular “eye” lesions, cutaneous lesions (facial/acral papulopustules) + vascular (SVC thrombosis), MSK, neuro, renal, GI, and cardiopulmonary disease
4
Q
1 cause of morbidity
A
ocular (blindness)
5
Q
pathology
A
neutrophilic infiltrate around vessels with LCV
6
Q
Tx
A
no gold standard of therapy
options: colchicine, dapsone, thalidomide, IFN-alpha-2a, MTX, TNF alpha inhibit, and azathioprine
7
Q
what is magic syndrome
A
behcet + relapsing polychondritis
