BADAS bowel-associated dermatosis arthritis syndrome

Question 1

who are the typical patients?

Answer 1

patients with GI disease (IBD, PUD, diverticulitis) OR
h/o Gastric surgery (gastric resection, jejunoileal bypass surgery, blind loops of bowel)

Note: PUD = peptic ulcer disease

Question 2

pathophys

Answer 2

overgrowth of bacteria with immune complexes deposited in the skin/synovium

Question 3

clinical features

Answer 3

classic rash (red papulopustules/tender SQ nodules/EN-like lesions) + malaise, fever, chills, arthralgia/myalgia, diarrhea, hepatic failure, kidney stones, gallstones

Question 4

Tx

Answer 4

surgical correction OR antibx (temporary improvement)

lesions last up to 1 month and recur frequently