Behavioral Neuro Flashcards

1
Q

What centers are located in the temporal lobe?

A
Wernicke's Speech Center (Dominant)
New Verbal memory(MTL Lt)
New visual memory (MTL rt)
Semantic Memory (lat)
Face/Object Recognition(post)
Emotional Processing(Amyg)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the common reason for Amnesic Syndromes?

A

Disruption of the Papez circuit

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the common reason for damage to the MTL?

A

Hypoxia, HS encephalitis, Early AZ, PCA strokes, surgery

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the common reason for damage to the Diencephalon?

A

Korsakoff Synd(thiamine def), thalamic strokes, surgery

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is the common reason for damage to the Basal Forebrain?

A

ACA Aneurism bleed or clipping w/ damage to small perforating arteries

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Where are memories stored?

A

Hippocampus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is the role of the frontal lobe?

A

Decides whether a retrieved memory is plausable for a given context (cant tell true mem from false mem)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What centers are in the Parietal Lobe?

A

Cortical Sensation
Praxis (Dom lobe)
Spatial Orientation (non-dom lobe)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

WHat is the purpose of the Non-dominant Parietal lobe?

A

Neglect
Anosagnosia
Dressing Apraxia
Visuo-spatial Disorientation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What centers are found in the Frontal lobe?

A

Broca’s speech center (Dom)
Executive functions(Bi)
Attention(Bi) -Social Cognition

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What disfunction is associated with the MDPC?

A

Akinetic mutism, withdrawl, lack of initiative, poverty of speech

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What disfunction is associated with the DLPC?

A

Impaired Abstraction and logical thinking, poor planning, poor judgement, impaired working memory and attn, poor memory organization

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What disfunction is associated with the OFC?

A

Impulsive and antisocial behavior, high risk behavior, stimulus boundness, unstable mood

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is the role of Wernicke’s area?

A

Decoding and Generating speech

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the role of Broca’s area?

A

Motor part of speech

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What happens if the connection between Wernicke’s and Broca’s is lesioned?

A

Pt can understand language but cannot formulate a response

17
Q

What is Apraxia?

A

Loss of the ability to perform a learned, familiar, purposeful motor act. HAve desire and Phys ability to do so.

18
Q

What is Prosopagnosia?

A

Face Blindness- cant recognize familiar faces

19
Q

WHat are areas of focus in the patient interview?

A
Cog Domains effected
Progression of problems
Insignt into condition
ADLs
Mood
ASK FAMILY SAME QUESTIONS!
20
Q

What labs should be done in Eval of Dementia?

A

Imaging study (MRI)
Blood work for rev causes: B12, TSH, LFTs, BMP, CBC
(Some: RPR, HIV, ApoE4)

21
Q

What is the Progression of Alzheimer’s disease?

A

CC formation of new memories
Prog: Visuospatial, naming and semantic memory
Orientaton impaired
Symp onset later in life

22
Q

What is mild cognitive impairment in AD?

A

There is a decline from normal but the Pt can still live independantly.

23
Q

WHat are the features of Frontotemporal Dementia?

A

Most Underdiagnosed
Heterogeneous presentation
CC: Beh change, Imp speech, dysexecutive synd
Earlier onset

24
Q

What are the traits of Subcortical dementia?

A

Pres with Slowed Psychomotor speed, memory loss, exec dysfunction
Assoc. w/ basal ganglia dis, demyelination, vascualr events

25
What are the features of Dementia wit Lewy bodies?
Central: Dysexecutive syndrome Core: Visual hallucinations Parkinsonism Fluct cognition
26
What are the features suggestive of DLB?
REM sleep behavior disorder, neuroleptic sensitivity, PET/SPECT
27
What are the types of Vascular Dementia?
Multi infarct Dementia | Diffuse White Matter Disease
28
What is the Tx of Dementia?
``` AChE inhibitors -Donepezil -Rivastigmine -Galantamine Slow or stabilize, don't stop Decline if discontinued! ```
29
What are the SA of AChEIs?
GI disturbance Vivid Dreams Inc Agitation
30
When is memantine used?
Moderate to Advanced AD. (NMDA receptor leak current blocker)
31
What medications should be limited in AD?
``` Anticholinergic meds (tylenol PM) Sedatives ```
32
WHat is the Tx of Dementia?
Anti Depressants as needed Mood stabilizers Atypical Antipsychotics (Quetiapine least anti Dop eff)
33
How Can Dementia be prevented?
Exercise! Healthy Diet (Mediterranean diet) Cognitive Activity