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BBDAY2 Flashcards

1
Q

found on GLYCOPHORIN A

A

MN antigens

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2
Q

MN antigens

M has a:

A

serine and glycine

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3
Q

MN antigens

N has a:

A

leucine and glutamic acid

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4
Q

easily destroyed or removed by enzymes

A

MN ag

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5
Q

located on GLYCOPHORIN B

A

Ss antigens

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6
Q

amino acid residue at position 1 and 5

A

MN antigens

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7
Q

amino acid at position 29

A

Ss antigens

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8
Q

Ss antigens

S has:

A

methionine

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9
Q

Ss antigens

s has:

A

threonine

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10
Q

Ss antigens immunoglobulin

A

IgG

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11
Q

enhanced by acidification of serum

A

Anti-M

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12
Q

Anti-M immunoglobulin

A

IgM or IgG

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13
Q

pH dependent, glucose dependent antibody

A

Anti-M

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14
Q

anti-M reacting best at what pH

A

6.5

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15
Q

Anti-N immunoglobulin

A

IgM or IgG

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16
Q

Seen in renal patients who are dialyzed on equipment sterilized with formaldehyde

A

Anti-N

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17
Q

produced from the plant Iberis amara

anti-M lectin
anti-N lectin

A

anti-M lectin

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18
Q

produced from the plant graminea

anti-M lectin
anti-N lectin

A

anti-N lectin

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19
Q

implicated with severe hemolytic transfusion reaction with hemoglobinuria and HDN

A

Ant-S and Anti-s

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20
Q

Ant-S and Anti-s immunoglobulin

A

IgG

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21
Q

individuals appeared to be M-N-

EN(a-b-) phenotype
Mk phenotype
U-phenotype

A

EN(a-b-) phenotype

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22
Q

resistant to P. falciparum merozoites

A

M-N-

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23
Q

they had a normal hematologic picture

EN(a-b-) phenotype
Mk phenotype
U-phenotype

A

Mk phenotype

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24
Q

typically IgG and has been reported to cause severe and fatal HTRs and HDN

EN(a-b-) phenotype
Mk phenotype
U-phenotype

A

U-phenotype

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25
Q

rabbits immunized with human blood

A

P+P-

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26
Q

P1 detectable antigens:
P1 possible antibodies:

A

P1,P,Pk
None

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27
Q

P2 detectable antigens:
P2 possible antibodies:

A

P, Pk
Anti-P1

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28
Q

p detectable antigens:
p possible antibodies:

A

none
Anti-PP1PK

29
Q

Anti-PP1PK AKA:

A

Anti-Tja

30
Q

P1K detectable antigens:
P1K possible antibodies:

A

P1,PK
Anti-P

31
Q

P2K detectable antigens:
P2K possible antibodies:

A

pk
Anti-P, Anti-P1

32
Q

common, naturally occuring IgM antibody in the sera of P2 individuals

A

Anti-P1

33
Q

observed in individuals infected with HYDATID DISEASE

A

Anti-P1

34
Q

assoc. with fasciolosis, clonorchis sinensis, and opistorchis veverrini infections

A

Anti-P1

35
Q

assoc, with spontaneous abortions in early pregnancy

A

Anti-PP1PK

36
Q

naturally occuring alloantibody in the sera of all Pk individuals

A

Anti-P

37
Q

rarely seen in blood bank but very significant in transfusion

A

anti-P

38
Q

Anti-P immunoglobulin

A

IgG

39
Q

seen in px with Paroxysmal Cold Hemoglobinuria

A

Anti-P

40
Q

antibody activitiy is biphasic

A

Anti-P

41
Q

demonstrated by the donath-landsteinder test

A

Anti-P

42
Q

has been reported in the serum of P1 individuals with biliary cirrhosis and autoimmune hemolytic anemia

A

Anti-Pk

43
Q

Assoc, with HEMPAS and CDA

A

I and i antigens

44
Q

common autoantibody that can be benign or pathologic

A

anti-I

45
Q

demonstrates strong reactions with adult cells and weak reactions with cord cells

A

anti-I

46
Q

CDA and HEMPA is assoc. with much greater ___

A

i

47
Q

not assoc. with HDN because the antigen is poorly expressed on infant red cells

A

anti-I

48
Q

not assoc. with in vivo red cell destruction/hemolysis

Benign anti-I
Pathologic Anti-I

A

Benign anti-I

49
Q

usually reacts only at 4C

Benign anti-I
Pathologic Anti-I

A

Benign anti-I

50
Q

broader thermal range of acitivity reacting upto 30 to 32C

Benign anti-I
Pathologic Anti-I

A

Pathologic Anti-I

51
Q

attach in vivo and cause autoagglutination and vascular occlusion or intravascular hemolysis

Benign anti-I
Pathologic Anti-I

A

Pathologic Anti-I

52
Q

Raynauds phenomenon

Benign anti-I
Pathologic Anti-I

A

Pathologic Anti-I

53
Q

stimulated by microorganisms: M, pneumoniae, L. monocytogenes

A

Autoanti-I

54
Q

Most autoanti-I are:

A

IgM

55
Q

Anti-i reacts best with saline suspended cells at what temperature?

A

4C

56
Q

assoc. with infectious mononucleosis (Epstein-Barr virus infection)

A

Anti-i

57
Q

found in Melanesians and the Yanomama Indians

A

Anti-It

58
Q

assoc. with Hodgkins disease

A

Anti-It

59
Q

rated second only to D in terms of immunogenicity

A

Kell antigens

60
Q

expression very weak on McLeid phenotype cells

A

Kell antigens

61
Q

common encountered in blood bank

A

AntiK

62
Q

Kell 1

A

K
kell

63
Q

Kell 2

A

k
Cellano

64
Q

Kell 3

A

Kpa
Penney

65
Q

Kell 4

A

Kpb
Rautenberg

66
Q

Kell 6

A

Jsa
Sutter

67
Q

kell 7

A

Jsb
Matthews

68
Q

resist infection by P.vivax and P. knowlesi

A

Fy(a-b-)

69
Q
A

BB (3 decks)

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