BBDAY2 Flashcards

1
Q

found on GLYCOPHORIN A

A

MN antigens

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2
Q

MN antigens

M has a:

A

serine and glycine

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3
Q

MN antigens

N has a:

A

leucine and glutamic acid

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4
Q

easily destroyed or removed by enzymes

A

MN ag

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5
Q

located on GLYCOPHORIN B

A

Ss antigens

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6
Q

amino acid residue at position 1 and 5

A

MN antigens

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7
Q

amino acid at position 29

A

Ss antigens

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8
Q

Ss antigens

S has:

A

methionine

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9
Q

Ss antigens

s has:

A

threonine

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10
Q

Ss antigens immunoglobulin

A

IgG

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11
Q

enhanced by acidification of serum

A

Anti-M

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12
Q

Anti-M immunoglobulin

A

IgM or IgG

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13
Q

pH dependent, glucose dependent antibody

A

Anti-M

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14
Q

anti-M reacting best at what pH

A

6.5

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15
Q

Anti-N immunoglobulin

A

IgM or IgG

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16
Q

Seen in renal patients who are dialyzed on equipment sterilized with formaldehyde

A

Anti-N

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17
Q

produced from the plant Iberis amara

anti-M lectin
anti-N lectin

A

anti-M lectin

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18
Q

produced from the plant graminea

anti-M lectin
anti-N lectin

A

anti-N lectin

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19
Q

implicated with severe hemolytic transfusion reaction with hemoglobinuria and HDN

A

Ant-S and Anti-s

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20
Q

Ant-S and Anti-s immunoglobulin

A

IgG

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21
Q

individuals appeared to be M-N-

EN(a-b-) phenotype
Mk phenotype
U-phenotype

A

EN(a-b-) phenotype

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22
Q

resistant to P. falciparum merozoites

A

M-N-

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23
Q

they had a normal hematologic picture

EN(a-b-) phenotype
Mk phenotype
U-phenotype

A

Mk phenotype

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24
Q

typically IgG and has been reported to cause severe and fatal HTRs and HDN

EN(a-b-) phenotype
Mk phenotype
U-phenotype

A

U-phenotype

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25
rabbits immunized with human blood
P+P-
26
P1 detectable antigens: P1 possible antibodies:
P1,P,Pk None
27
P2 detectable antigens: P2 possible antibodies:
P, Pk Anti-P1
28
p detectable antigens: p possible antibodies:
none Anti-PP1PK
29
Anti-PP1PK AKA:
Anti-Tja
30
P1K detectable antigens: P1K possible antibodies:
P1,PK Anti-P
31
P2K detectable antigens: P2K possible antibodies:
pk Anti-P, Anti-P1
32
common, naturally occuring IgM antibody in the sera of P2 individuals
Anti-P1
33
observed in individuals infected with HYDATID DISEASE
Anti-P1
34
assoc. with fasciolosis, clonorchis sinensis, and opistorchis veverrini infections
Anti-P1
35
assoc, with spontaneous abortions in early pregnancy
Anti-PP1PK
36
naturally occuring alloantibody in the sera of all Pk individuals
Anti-P
37
rarely seen in blood bank but very significant in transfusion
anti-P
38
Anti-P immunoglobulin
IgG
39
seen in px with Paroxysmal Cold Hemoglobinuria
Anti-P
40
antibody activitiy is biphasic
Anti-P
41
demonstrated by the donath-landsteinder test
Anti-P
42
has been reported in the serum of P1 individuals with biliary cirrhosis and autoimmune hemolytic anemia
Anti-Pk
43
Assoc, with HEMPAS and CDA
I and i antigens
44
common autoantibody that can be benign or pathologic
anti-I
45
demonstrates strong reactions with adult cells and weak reactions with cord cells
anti-I
46
CDA and HEMPA is assoc. with much greater ___
i
47
not assoc. with HDN because the antigen is poorly expressed on infant red cells
anti-I
48
not assoc. with in vivo red cell destruction/hemolysis Benign anti-I Pathologic Anti-I
Benign anti-I
49
usually reacts only at 4C Benign anti-I Pathologic Anti-I
Benign anti-I
50
broader thermal range of acitivity reacting upto 30 to 32C Benign anti-I Pathologic Anti-I
Pathologic Anti-I
51
attach in vivo and cause autoagglutination and vascular occlusion or intravascular hemolysis Benign anti-I Pathologic Anti-I
Pathologic Anti-I
52
Raynauds phenomenon Benign anti-I Pathologic Anti-I
Pathologic Anti-I
53
stimulated by microorganisms: M, pneumoniae, L. monocytogenes
Autoanti-I
54
Most autoanti-I are:
IgM
55
Anti-i reacts best with saline suspended cells at what temperature?
4C
56
assoc. with infectious mononucleosis (Epstein-Barr virus infection)
Anti-i
57
found in Melanesians and the Yanomama Indians
Anti-It
58
assoc. with Hodgkins disease
Anti-It
59
rated second only to D in terms of immunogenicity
Kell antigens
60
expression very weak on McLeid phenotype cells
Kell antigens
61
common encountered in blood bank
AntiK
62
Kell 1
K kell
63
Kell 2
k Cellano
64
Kell 3
Kpa Penney
65
Kell 4
Kpb Rautenberg
66
Kell 6
Jsa Sutter
67
kell 7
Jsb Matthews
68
resist infection by P.vivax and P. knowlesi
Fy(a-b-)
69