BB DAY1 Flashcards
1
Q
Chromosome 1
A
Rh, Duffy
2
Q
Chromosome 4
A
MNS
3
Q
Chromosome 7
A
Kell
4
Q
Chromosome 9
A
ABO
5
Q
Chromosome 18
A
Kidd
6
Q
Chromosome 19
A
H, Lewis, Lutheran
7
Q
Chromosome 22
A
P1
8
Q
discovered ABO blood groups
A
karl landsteiner
9
Q
book of karl landteiner
A
SSR= the specificity of serolofical reactions
10
Q
discovered blood group AB
A
Sturle and von descatello
11
Q
one solid agglutinate
A
4+
12
Q
several large agglutinates
A
3+
13
Q
medium sized agglutinates
A
2+
14
Q
small agglutinates
A
1+
15
Q
tiny agglutinates
A
w+
16
Q
no agglutinates
A
0
17
Q
principle of gel technology
A
HEMAGGLUTINATION
18
Q
in gel tech, reactions are stable for observation or review for how many days?
A
2 to 3 days
19
Q
major advantage of gel technology
A
standardization
20
Q
major disadvantage of gel technology
A
purchase special equipment
21
Q
red cell suspension prep:
A
2-5% RBC
22
Q
solid band of agglutinated red cells at the top of the gel column
A
4+r
23
Q
predominant amount of agglutinated red cells towards the top of the gel column
A
3+
24
Q
red cell agglutinates dispersed througout the gel column with few agglutinates at the bottom of the microtubes
A
2+
25
red cell agglutinates predominantly observed in the lower half of the gel column with red cells in the bottom
1+
26
red cells forming a well delineated pellet in the bottom of the microtube
negative
27
layer of red cell agglutinates at the top of the gel column accompanied by a pellet of unagglutinated cells in the bottom of the microtube
mixed field
28
possible genotypes of A1
A1A1, A1O, A1A2
29
possible genotypes of A2
A2A2, A2O
30
possible genotypes of A1B
A1B
31
possible genotypes of A2B
A2B
32
possible genotypes of B
BB, BO
33
possible genotypes of O
OO
34
GLYCOSYLTRANSFERASE OF gene H
L-fucosyltransferase
35
GLYCOSYLTRANSFERASE OF gene a
N-acetylgalactosaminyltransferase
36
GLYCOSYLTRANSFERASE OF gene B
D-galactosyltransferase
37
GLYCOSYLTRANSFERASE OF gene AB
N-acetylgalactosaminyltransferase
D-galactosyltransferase
38
GLYCOSYLTRANSFERASE OF gene O
NONE
39
TYPE 1 or TYPE 2 Chains
Linkage Beta 1,3
Type 1
40
TYPE 1 or TYPE 2 Chains
Linkage Beta 1,4
Type 2
41
TYPE 1 or TYPE 2 Chains
Origin: Plasma
1
42
TYPE 1 or TYPE 2 Chains
Origin: synthesized on erythrocytic precursors
2
43
TYPE 1 or TYPE 2 Chains
controlling genes: H A B Se and Lewis
1
44
TYPE 1 or TYPE 2 Chains
controlling genes: H A B
2
45
other subgroups of A
weakly agglutinated
A3, Ax, Aend
46
other subgroups of A
no agglutination
Am, Ay, Ael
47
other subgroups of A
mixed field agglutination with anti-A and or anti-B
A3
48
other subgroups of A
weak agglutination with anti-AB only
Ax
49
other subgroups of A
< 10% red cells show very weak mf agglutination
Aend
50
other subgroups of A
no agglutination with anti-a and anti-b, secretors demonstrates quantities of A substance in saliva
Am
51
other subgroups of A
no agglutination with anti-a and anti-b, secretors contain small amount of A substance in saliva
Ay
52
other subgroups of A
no agglutination with anti-a and anti-b, secretors contain only H substance and no A substance in saliva
Ael
53
other subgroups of B weakly agglutinated
B3, Bx
54
other subgroups of B no agglutination
Bm Bel
55
other subgroups of B
mixed field agglutination with anti-A and or anti-B
B3
56
other subgroups of B
agglutination with anti-AB
Bx
57
H gene must be inherited to from the
ABO antigens
58
H genes codes for what enzyme?
Fucosyltransferase enzyme
59
produce anti-H
A1
60
produce anti-A1
A2
61
genotype of bombay phenotype
hh
62
bombay phenotype AKA
H null
63
A Bombay individual does not express
A, B, or H antigens
64
What antibodies are formed by a Bombay individual?
Anti-A, anti-B and anti-H
65
group O increase sa?
Anti-A
Anti-B
Anti-H
Anti-H
66
does not inherit H gene
classical bombay
parabombay
classical bombay
67
no H A B antigens
classical bombay
parabombay
classical bombay
68
designated as Oh
classical bombay
parabombay
classical bombay
69
inherits weak H gene
classical bombay
parabombay
parabombay
70
detectable a, b antigens but not detectable H antigen
classical bombay
parabombay
parabombay
71
designated as Ah, Bh or ABh
classical bombay
parabombay
parabombay
72
reported in persons of type O or B in association with severe infections caused by Proteus mirabilis
Acquired A antigen
73
associated with conditions such as "EPIC"
E, coli
Proteus vulgaris
Intestinal obstruction
Carcinoma
Acquired B antigen
74
immunoglobulin present in blood group A
IgM
75
immunoglobulin present in blood group B
IgM
76
immunoglobulin present in blood group O
IgG
77
TREATMENT FOR ABO-HDN
phototheraphy
78
ABO-HDN happens when
mother is group O
child is group A or B
79
Rh-HDN occurs in what type of mother and child:
Mother is Rh (-), child is Rh (+)
80
what is the specimen for determination of the secretor status
SALIVA
81
what is the principle for determination of the secretor status
Hemagglutination-Inhibition
82
Acquired B antigens have been found in:
Group A persons
83
Which typing results are most likely to occur when a patient has an acquired B antigen?
a. Anti-A 4+, anti-B-3+, A1 cells neg, B cells neg
b. Anti-A 3+, anti-B neg, A1 cells neg, B cells neg
c. Anti-A 4+, anti-B 1+, A1 cells neg, B cells 4+
d. Anti-A 4+, anti-B 4+, A1 cells 2+, B cells neg
c. Anti-A 4+, anti-B 1+, A1 cells neg, B cells 4+
84
Lectins are useful in determining the cause of abnormal reactions in blood bank serology. These lectins are frequently labeled as anti-H, anti-A1 etc. The nature of these lectins is explained by which of the following?
An early form of monoclonal antibody produced in nonvertebrates
A plant substance that chemically reacts with certain RBC antigens
Naturally occurring antibodies in certain plants
The ability of plants to respond to RBC antigens by antibody production
A plant substance that chemically reacts with certain RBC antigens
85
which lectins in BB agglutinates B cells
a. Bandeiraea simplicifolia
b. Dolichos biflorus
c. Ulex europaeus
a. Bandeiraea simplicifolia
86
which lectins in BB agglutinates A1 or A1B
a. Bandeiraea simplicifolia
b. Dolichos biflorus
c. Ulex europaeus
b. Dolichos biflorus
87
which lectins in BB agglutinates O cells
a. Bandeiraea simplicifolia
b. Dolichos biflorus
c. Ulex europaeus
c. Ulex europaeus
88
Which cells agglutinate most strongly with Ulex europaeus lectin?
O cells
89
weaky reacting or missing antibodies
Group 1 discrepancies
Group 2
Group 3
Group 4
Group 1
90
weaky reacting or missing antigens
Group 1 discrepancies
Group 2
Group 3
Group 4
Group 2
91
protein or plasma abnormalities resulting to rouleaux formation
Group 1 discrepancies
Group 2
Group 3
Group 4
Group 3
92
miscellaneous
Group 1 discrepancies
Group 2
Group 3
Group 4
Group 4
