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BB DAY1 Flashcards

1
Q

Chromosome 1

A

Rh, Duffy

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2
Q

Chromosome 4

A

MNS

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3
Q

Chromosome 7

A

Kell

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4
Q

Chromosome 9

A

ABO

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5
Q

Chromosome 18

A

Kidd

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6
Q

Chromosome 19

A

H, Lewis, Lutheran

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7
Q

Chromosome 22

A

P1

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8
Q

discovered ABO blood groups

A

karl landsteiner

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9
Q

book of karl landteiner

A

SSR= the specificity of serolofical reactions

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10
Q

discovered blood group AB

A

Sturle and von descatello

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11
Q

one solid agglutinate

A

4+

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12
Q

several large agglutinates

A

3+

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13
Q

medium sized agglutinates

A

2+

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14
Q

small agglutinates

A

1+

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15
Q

tiny agglutinates

A

w+

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16
Q

no agglutinates

A

0

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17
Q

principle of gel technology

A

HEMAGGLUTINATION

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18
Q

in gel tech, reactions are stable for observation or review for how many days?

A

2 to 3 days

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19
Q

major advantage of gel technology

A

standardization

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20
Q

major disadvantage of gel technology

A

purchase special equipment

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21
Q

red cell suspension prep:

A

2-5% RBC

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22
Q

solid band of agglutinated red cells at the top of the gel column

A

4+r

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23
Q

predominant amount of agglutinated red cells towards the top of the gel column

A

3+

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24
Q

red cell agglutinates dispersed througout the gel column with few agglutinates at the bottom of the microtubes

A

2+

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25
Q

red cell agglutinates predominantly observed in the lower half of the gel column with red cells in the bottom

A

1+

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26
Q

red cells forming a well delineated pellet in the bottom of the microtube

A

negative

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27
Q

layer of red cell agglutinates at the top of the gel column accompanied by a pellet of unagglutinated cells in the bottom of the microtube

A

mixed field

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28
Q

possible genotypes of A1

A

A1A1, A1O, A1A2

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29
Q

possible genotypes of A2

A

A2A2, A2O

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30
Q

possible genotypes of A1B

A

A1B

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31
Q

possible genotypes of A2B

A

A2B

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32
Q

possible genotypes of B

A

BB, BO

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33
Q

possible genotypes of O

A

OO

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34
Q

GLYCOSYLTRANSFERASE OF gene H

A

L-fucosyltransferase

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35
Q

GLYCOSYLTRANSFERASE OF gene a

A

N-acetylgalactosaminyltransferase

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36
Q

GLYCOSYLTRANSFERASE OF gene B

A

D-galactosyltransferase

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37
Q

GLYCOSYLTRANSFERASE OF gene AB

A

N-acetylgalactosaminyltransferase
D-galactosyltransferase

38
Q

GLYCOSYLTRANSFERASE OF gene O

A

NONE

39
Q

TYPE 1 or TYPE 2 Chains

Linkage Beta 1,3

A

Type 1

40
Q

TYPE 1 or TYPE 2 Chains

Linkage Beta 1,4

A

Type 2

41
Q

TYPE 1 or TYPE 2 Chains

Origin: Plasma

A

1

42
Q

TYPE 1 or TYPE 2 Chains

Origin: synthesized on erythrocytic precursors

A

2

43
Q

TYPE 1 or TYPE 2 Chains

controlling genes: H A B Se and Lewis

A

1

44
Q

TYPE 1 or TYPE 2 Chains

controlling genes: H A B

A

2

45
Q

other subgroups of A

weakly agglutinated

A

A3, Ax, Aend

46
Q

other subgroups of A

no agglutination

A

Am, Ay, Ael

47
Q

other subgroups of A

mixed field agglutination with anti-A and or anti-B

A

A3

48
Q

other subgroups of A

weak agglutination with anti-AB only

A

Ax

49
Q

other subgroups of A

< 10% red cells show very weak mf agglutination

A

Aend

50
Q

other subgroups of A

no agglutination with anti-a and anti-b, secretors demonstrates quantities of A substance in saliva

A

Am

51
Q

other subgroups of A

no agglutination with anti-a and anti-b, secretors contain small amount of A substance in saliva

A

Ay

52
Q

other subgroups of A

no agglutination with anti-a and anti-b, secretors contain only H substance and no A substance in saliva

A

Ael

53
Q

other subgroups of B weakly agglutinated

A

B3, Bx

54
Q

other subgroups of B no agglutination

A

Bm Bel

55
Q

other subgroups of B

mixed field agglutination with anti-A and or anti-B

A

B3

56
Q

other subgroups of B

agglutination with anti-AB

A

Bx

57
Q

H gene must be inherited to from the

A

ABO antigens

58
Q

H genes codes for what enzyme?

A

Fucosyltransferase enzyme

59
Q

produce anti-H

A

A1

60
Q

produce anti-A1

A

A2

61
Q

genotype of bombay phenotype

A

hh

62
Q

bombay phenotype AKA

A

H null

63
Q

A Bombay individual does not express

A

A, B, or H antigens

64
Q

What antibodies are formed by a Bombay individual?

A

Anti-A, anti-B and anti-H

65
Q

group O increase sa?

Anti-A
Anti-B
Anti-H

A

Anti-H

66
Q

does not inherit H gene

classical bombay
parabombay

A

classical bombay

67
Q

no H A B antigens

classical bombay
parabombay

A

classical bombay

68
Q

designated as Oh

classical bombay
parabombay

A

classical bombay

69
Q

inherits weak H gene

classical bombay
parabombay

A

parabombay

70
Q

detectable a, b antigens but not detectable H antigen

classical bombay
parabombay

A

parabombay

71
Q

designated as Ah, Bh or ABh

classical bombay
parabombay

A

parabombay

72
Q

reported in persons of type O or B in association with severe infections caused by Proteus mirabilis

A

Acquired A antigen

73
Q

associated with conditions such as “EPIC”

E, coli
Proteus vulgaris
Intestinal obstruction
Carcinoma

A

Acquired B antigen

74
Q

immunoglobulin present in blood group A

A

IgM

75
Q

immunoglobulin present in blood group B

A

IgM

76
Q

immunoglobulin present in blood group O

A

IgG

77
Q

TREATMENT FOR ABO-HDN

A

phototheraphy

78
Q

ABO-HDN happens when

A

mother is group O
child is group A or B

79
Q

Rh-HDN occurs in what type of mother and child:

A

Mother is Rh (-), child is Rh (+)

80
Q

what is the specimen for determination of the secretor status

A

SALIVA

81
Q

what is the principle for determination of the secretor status

A

Hemagglutination-Inhibition

82
Q

Acquired B antigens have been found in:

A

Group A persons

83
Q

Which typing results are most likely to occur when a patient has an acquired B antigen?

a. Anti-A 4+, anti-B-3+, A1 cells neg, B cells neg
b. Anti-A 3+, anti-B neg, A1 cells neg, B cells neg
c. Anti-A 4+, anti-B 1+, A1 cells neg, B cells 4+
d. Anti-A 4+, anti-B 4+, A1 cells 2+, B cells neg

A

c. Anti-A 4+, anti-B 1+, A1 cells neg, B cells 4+

84
Q

Lectins are useful in determining the cause of abnormal reactions in blood bank serology. These lectins are frequently labeled as anti-H, anti-A1 etc. The nature of these lectins is explained by which of the following?

An early form of monoclonal antibody produced in nonvertebrates

A plant substance that chemically reacts with certain RBC antigens

Naturally occurring antibodies in certain plants

The ability of plants to respond to RBC antigens by antibody production

A

A plant substance that chemically reacts with certain RBC antigens

85
Q

which lectins in BB agglutinates B cells

a. Bandeiraea simplicifolia
b. Dolichos biflorus
c. Ulex europaeus

A

a. Bandeiraea simplicifolia

86
Q

which lectins in BB agglutinates A1 or A1B

a. Bandeiraea simplicifolia
b. Dolichos biflorus
c. Ulex europaeus

A

b. Dolichos biflorus

87
Q

which lectins in BB agglutinates O cells

a. Bandeiraea simplicifolia
b. Dolichos biflorus
c. Ulex europaeus

A

c. Ulex europaeus

88
Q

Which cells agglutinate most strongly with Ulex europaeus lectin?

A

O cells

89
Q

weaky reacting or missing antibodies

Group 1 discrepancies
Group 2
Group 3
Group 4

A

Group 1

90
Q

weaky reacting or missing antigens

Group 1 discrepancies
Group 2
Group 3
Group 4

A

Group 2

91
Q

protein or plasma abnormalities resulting to rouleaux formation

Group 1 discrepancies
Group 2
Group 3
Group 4

A

Group 3

92
Q

miscellaneous

Group 1 discrepancies
Group 2
Group 3
Group 4

A

Group 4

BB (3 decks)

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