BBB Penetrability Flashcards

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1
Q

BBB Penetration +/- Inflammation (8)

A
Sulfonamides
Chloramphenicol
Rifampicin
Isoniazid
Trimethroprim
Metronidazole
Fluconazole
Flucytosine
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2
Q

BBB Penetration IF + Inflammation (6)

A
Penicillins
Imipenem + Cilastatin
Meopenem
Aztreonam
Cirpofloxacin
Vancomycin 

Cephalosporins

  • 2 cefuroxime
  • 3 Gen parenteral (except cefoperazone)
  • 4
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3
Q

BBB Penetration Minimal even if + Inflammation (4)

A

Aminoglycosides
Tetracyclines
Lincosamides
Macrolides

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4
Q

BBB Penetration NONE (3)

A

Polymixins
Cephalosporins (1/2nd Gen)
Amphotericin B

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