BB Protocol 1 Flashcards

1
Q

CRAS & Phone ward? (4)

A

CRAS: Ab+
Phone ward: Ab+, XM+, D- after unmatched issuing

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2
Q

ABO current-history discrepancy? (3)

A

1.Repeat with same sample
2.Repeat with new sample

If 2nd = History, hold last 6h T&S & repeat those without history

If 2nd = 1st != History, confirm patient identity with ward, deactivate ABO history, report T&S, inform Hematologist & SMT

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3
Q

Inform hematologist? (7)

A
  1. ABO anomaly / current-history discrepancy
  2. Mixed field
  3. Need blood before AbID / Phenotyping finished
  4. Issue Incompatible-IAT before hematologist Authorize
  5. HB<7, AutoAb case, Phenotyping done but unit not requested
  6. D+ unit to D- patient
  7. TR discrepancy
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4
Q

hematologist review? (4)

A
  1. Request >2 D- RBC / week
  2. Request D- PLT
  3. Reserve >8 PLT
  4. Rare blood group
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5
Q

Autologous? (2)

A
  1. Physician should confirm with RC first
  2. Autologous units are separated & should not be transfused to other patients
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6
Q

Post-BMT? (2)

A
  1. ABO depends on both the donor & the recipient
  2. RBC should be irradiated +-CMV
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7
Q

Storage time? (3)

A

Patient T&S sample: 21d, discard 1 week each SUN
Pilot segment: 40d
Hardcopy (WS, Report, IQC): 4y

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8
Q

TAT? (2)

A

Unmatched O: 5min
Unmatched group-specific: 20min

T&S: Urgent = 1h, non-Urgent = 2h, Ab+ = >2h

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9
Q

PAC? (2)

A
  1. PAC form is required for registration
  2. If Ab+, Repeat T&S <2d before OT
  3. PAC case is valid till OT+1 / 14 days, after 12th day, extension by 1 day is possible
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10
Q

Demographic? (1)

A

Merging UC to HKID is not acceptable.

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11
Q

Product recall? (1)

A

BST done for day 2 PLT
day 3 PLT release to BB
day 3 ~ 4 BST become + / Donor sick
Shift MT should check email at the end of each shift

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12
Q

Product Lookback? (1)

A

Donor NAT- become NAT+ in later testing due to viral window period.
Recipient should be informed

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13
Q

Emergency release? (1)

A

units without BST & NAT are released to BB due to shortage of supply

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14
Q

TR & TI? (1)

A

Transfusion reaction is investigated using pre, post, and used bag of unit.

Transfusion incident is reported through AIRS by both BB & ward.

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15
Q

Rare blood group & special phenotype (2)

A

Rare blood group: ParaBombay
Special phenotype: unit required for Ag-Neg / Phenotype matched has a chance of <1/1000 when picked randomly. Ag distribution program is available for this calculation

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16
Q

Used blood bag? (1)

A

Stamp transfusion note
PCA sign, MT sign
blood bag store at 4C
discard after 1d

17
Q

OT delivery & return? (1)

A

OT 0900~2030 MON~SUN (~1800 if PCA on leave)

18
Q

unit return? (2)

A
  1. PI173
  2. Fit unit if it meets storage condition (leave 4C within 30min for RBC, within 2h after issued for PLT, always unfit for plasma & CRYO), & actual condition (cold to touch for RBC, not cold to touch for PLT)
19
Q

Collection of unit? (3)

A
  1. RBC >1 unit is for OT only
  2. 1 container for each unit type
  3. ice pack can keep 4C for 150min, validation annually
  4. downtime bearer memo PR40
  5. IAT-incompatible PI335, Unmatched PI337
20
Q

ABO anomaly? (3)

A
  1. Confirm patient ABO / Transfusion / BMT history with ward
  2. New sample for Ix during office hour
  3. Refer to RC when necessary
  4. Report Unknown & AbID pending
    reserve IAT-compatible O RBC (request RC in case of Bombay/ParaBombay)
    issue AB plasma if required
    issue AB PLT / other group without Anti-A & Anti-B PLT if required (AB PLT only for <1y)
  5. ABO will be Authorized with T&S remark indicating subtype, FXM / CXM of group-matched / O RBC according to the remark
21
Q

Weak / Partial D? (2)

A
  1. Regard as Rh- before confirmation
  2. For confirmed partial D, considered as Rh- as recipient but Rh+ as donor
22
Q

Unmatched blood? (4)

A
  1. PI337
  2. Unmatched O can be issued without T&S sample
  3. O- to
    Anti-D induced HDFN
    > Rh- with Anti-D
    > Rh- young female
    > Rh? white young female
    > Other Rh-
    #O+ can be given with physician consent
  4. For Group-specific, ABO is done by tube method, including 2nd ABO
23
Q

ABO Rh consideration for PLT & Plasma? (7)

A

Plasma / CRP
1. Same group > ABO-compatible > AB
2. Rh irrelevant

PLT
1. ABO identical / plasma compatible for <1y
2. Any group, LT <6 unit / d for plasma ABO-incompatible
3. AB PLT for Unknown ABO
4. Rh+ PLT to Rh- require physician consent

CRYO
1. Same as PLT but Rh irrelevant

24
Q

PLT & Plasma request? (3)

A
  1. Unlike the 3d validity for RBC, T&S record in CMC is always valid for issuing PLT & Plasma
  2. After reporting, PLT is reserve till stated date, Plasma is 7d, CRP/CRYO is 3d
25
Q

Thawing Plasma & CRYO? (2)

A

Thawing start after receiving PI174 by fax
Plasma: Thaw 20min, store at 4C, used within 1d
CRYO: Thaw 5min, store at RT, used within 4h

26
Q

Blood reservation for adult and <120d? (7)

A

Adult:
3d & <T&S&unit expiry

<120d:
1. ABO-compatible with both mom & baby
2. 2359 of T&S&unit expiry for Minipack
3. max. 3d, <T&S expiry / <=5th day of unit collection for WB
4.test infant plasma for Anti-A,Anti-B for cases with non-group specific transfusion
5. If baby Rh+ mom Rh-
-If DAT- & Mom Ab screen-, reserve Rh- ABO compatible / Rh+
-Otherwise we must reserve Rh- ABO compatible until Anti-D induced HDFN is rule out
Theoretically Rh+ is not problematic only when baby & mother are both Rh+
6. For abandoned baby, determine Rh based on baby’s plasma DAT & Ab screen. reserve group O.

27
Q

T&S validity is 1100 at 3rd day, which sometimes determine the RBC reservation validity, can I extend the RBC reservation validity? (1)

A

Yes.
The 1100 can be extended to 2100 if necessary, T&S validity is extended accordingly

28
Q

I request special RBC unit from RC, 3 hours later the unit arrived, can I perform FXM using plasma from the same T&S sample? (1)

A

Yes.
As long as the plasma quantity is sufficient & collection time <1d

29
Q

Storage temperature of RBC, Plasma/CRYO/CRP, and PLT? (3)

A

RBC: 2~6C
Plasma/CRYP/CRP: <-30C
PLT: 20~24C

30
Q

Visual inspection of unit? (6)

A
  1. Donor blood group (verification)
  2. Any leakage
  3. Any abnormal appearance
  4. Large blood clot
  5. Discoloration
  6. Missing administration port
31
Q

T&S validity? (3)

A

If Ab-:
3rd day 1100 (start from day 0)
For infant <120d, 119th day 1100 (start from day 0)
T&S valid = CXM issue ok
For Extension of T&S validity, patient should be Ab-, No transfusion & Not pregnant within 3m. Max. extension is +3days each time, & should not exceed 12th day. PI334.

32
Q

Ab+, new case, AbID pending, compatible-IAT not available, what would you do? (1)

A

Inform ward, if blood is required as emergency, group-matched least incompatible blood may be issued.

33
Q

Ab+, old case, what would you do? (1)

A

Reserve random/Ag-/Phenotype matched compatible-IAT according to T&S remark.If T&S remark said AIHA case, reserve phenotype-matched incompatible IAT according to phenotype described (/self-performed phenotyping result?). Ask physician to sign PI335

34
Q

baby case Ab status? (1)

A

baby plasma DAT+, mom plasma Ab screen- = Ab+
DAT turn -, Ab turn - automatically

35
Q

Ab screening? (3)

A
  1. Panel cell 1&2 included Rh, Kk, Duffy, Kid, MNSs, Lewis
  2. Panel cell 3 is Mur+ for Anti-Mi detection
36
Q

Special consideration regarding Rh

A
  1. Rh- Anti-D -, consider Rh- for pregnant women only
  2. PLT Rh- is usually not available, for patient with Rh- Anti-D - , consider RhIg to prevent immunization, for patient with Rh- Anti-D +, Rh Ag in PLT is insignificant so HTR probably won’t happen.