BB D-4 Flashcards
What is the component of choice for someone who needs a RBC transfusion when there is a history of febrile transfusion reactions?
Leukocyte-reduced RBCs
Which of the following is acceptable to be given intravenously with a blood transfusion?
Physiologic saline
Hemolytic transfusion reactions are the most serious type of reactions to blood transfusion. The majority of hemolytic transfusion reactions are caused by ____ errors.
CLERICAL
Occasionally, patients have an anaphylactic reaction to a specific immunoglobulin class during a transfusion. Which immunoglobulin class is most often implicated?
IgA
A transfusion reaction is reported by the nursing unit on patient. The nurse reports that the patient had chills, fever, and back pain within a few minutes of starting the unit. The nurse asks what s/he should do.
Discontinue the unit, keep the line open
All paperwork checks on this transfusion reaction are OK. The pretransfusion sample has straw-colored plasma. The post-transfusion sample has RED-tinged plasma. This is indicative of a(an):
Intravascular transfusion reaction
A patient experiences severe rigors and goes into shock after receiving part of a unit of RBC. The patient’s temperature, which was 37.5°C pretransfusion, is now 40.0°C. Which of the following is the most likely type of reaction?
SEPTIC
Which is the class of immunoglobulin uniquely associated with hemolytic disease of the newborn (HDN)?
IgG
What is the principle of the Kleihauer-Betke stain?
Adult hemoglobin is more soluble in acid buffer than fetal hemoglobin.
The temperature of a blood refrigerator without a continuous recording device should be recorded:
EVERY 4 HRS
When should quality control be performed on routine blood typing reagents?
ONCE DAILY
Kernicterus is caused by the effects of:
Unconjugated bilirubin
All of the following are routinely performed on a cord blood sample except:
ANTIBODY SCREEN
A patient had a transfusion reaction to packed red blood cells. The medical laboratory scientist began the laboratory investigation of the transfusion reaction by assembling pre- and post-transfusion specimens and all paperwork and computer printouts. What should he do next?
Check for a clerical error(s)
What may be found in the serum of a person who is exhibiting signs of TRALI (transfusion-related acute lung injury)?
Antileukocyte antibody
Which type of transfusion reaction occurs in about 1% of all transfusions, results in a temperature rise of 1°C or higher, is associated with blood component transfusion, and is not related to the patient’s medical condition?
Febrile nonhemolytic reaction
What would be the result of group A blood given to an O patient?
Immediate hemolytic transfusion reaction
What component is most frequently involved with transfusion-associated sepsis?
PLATELETS
Fatal transfusion reactions are mostly caused by?
CLERICAL ERRORS
Pain at infusion site and hypotension are observed with what type of reaction?
Acute hemolytic transfusion reaction
Irradiation of blood is performed to prevent?
Transfusion-associated graft-versus-host disease
The only presenting sign most often accompanying a delayed hemolytic transfusion reaction is?
Unexplained decrease in hemoglobin
Which transfusion reaction presents with fever, maculopapular rash, watery diarrhea, abnormal liver function, and pancytopenia?
Transfusion-associated graft-versus-host disease
Characteristic of iron overload
DELAYED, NONIMMUNE COMPLICATION
CHELATING AGENTS ARE USED
MULTIORGAN DAMAGE MAY OCCUR
Which of the following tests is useful to confirm that a patient or donor is infected with HCV?
RIBA
The first retrovirus to be associated with human disease was:
HTLV-I
What is the most common parasitic complication of transfusion?
PLASMODIUM SPECIES
The endpoint of the gel test is detected by:
AGGLUTINATION
The endpoint of the SPRCA test is detected by:
Attachment of indicator cells
An advantage for both gel and solid-phase technology is:
STANDARDIZATION
Incubation period for the gel test
15 MINS
Centrifugation time for the test:
10 MINS
An important determinant of platelet viability following storage is:
PLASMA PH
Irradiation of a unit of Red Blood Cells is done to prevent the replication of donor:
LYMPHOCYTES
The Liley method of predicting the severity of hemolytic disease of the newborn is based on the amniotic fluid:
Change in optical density measured to 450 nm
Kernicterus is caused by the effects of:
Unconjugated bilirubin
Blood for intrauterine transfusion should be all of the following, EXCEPT:
More than 7 days old
RhIG is indicated for:
Mothers who are Rh-negative
Which of the following is the preferred specimen for the initial compatibility testing in exchange transfusion therapy?
Maternal serum
Posttransfusion purpura (PTP) is usually caused by:
Anti-HPA
In a delayed transfusion reaction, the causative antibody is generally too weak to be detected in routine compatibility testing and antibody screening tests, but is typically detectable at what point after transfusion?
3 TO 7 DAYS
Which of the following transfusion reactions is characterized by high fever, shock, hemoglobinuria, DIC and renal failure?
BACTERIAL CONTAMINATION
Hemoglobinuria, hypotension and generalized bleeding are symptoms of which of the following transfusion reactions?
HEMOLYTIC
The MOST COMMON INITIAL clinical manifestation of a hemolytic transfusion reaction is:
FEVER
Leukocyte-poor red blood cells would most likely be indicated for patients with a history of:
Febrile nonhemolytic transfusion reaction
Hives and itching are symptoms of which of the following transfusion reactions?
ALLERGIC
The laboratory assay of brain natriuretic peptide (BNP) may be used to aid in the diagnosis of:
TACO
The most common isolate found in RBC units
Yersinia enterocolitca
Organisms most frequently recovered from donated blood and contamination of platelets:
Staphylococcus epidermidis, Bacillus cereus
Congestive heart failure, severe headache and/or peripheral edema occurring soon after transfusion is indicative of which type of transfusion reaction?
Circulatory overload
The most frequent transfusion-associated disease complication of blood transfusion is:
HEPATITIS
