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BLOOD BANKING > BB D-4 > Flashcards

BB D-4 Flashcards

1
Q

What is the component of choice for someone who needs a RBC transfusion when there is a history of febrile transfusion reactions?

A

Leukocyte-reduced RBCs

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2
Q

Which of the following is acceptable to be given intravenously with a blood transfusion?

A

Physiologic saline

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3
Q

Hemolytic transfusion reactions are the most serious type of reactions to blood transfusion. The majority of hemolytic transfusion reactions are caused by ____ errors.

A

CLERICAL

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4
Q

Occasionally, patients have an anaphylactic reaction to a specific immunoglobulin class during a transfusion. Which immunoglobulin class is most often implicated?

A

IgA

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5
Q

A transfusion reaction is reported by the nursing unit on patient. The nurse reports that the patient had chills, fever, and back pain within a few minutes of starting the unit. The nurse asks what s/he should do.

A

Discontinue the unit, keep the line open

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6
Q

All paperwork checks on this transfusion reaction are OK. The pretransfusion sample has straw-colored plasma. The post-transfusion sample has RED-tinged plasma. This is indicative of a(an):

A

Intravascular transfusion reaction

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7
Q

A patient experiences severe rigors and goes into shock after receiving part of a unit of RBC. The patient’s temperature, which was 37.5°C pretransfusion, is now 40.0°C. Which of the following is the most likely type of reaction?

A

SEPTIC

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8
Q

Which is the class of immunoglobulin uniquely associated with hemolytic disease of the newborn (HDN)?

A

IgG

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9
Q

What is the principle of the Kleihauer-Betke stain?

A

Adult hemoglobin is more soluble in acid buffer than fetal hemoglobin.

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10
Q

The temperature of a blood refrigerator without a continuous recording device should be recorded:

A

EVERY 4 HRS

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11
Q

When should quality control be performed on routine blood typing reagents?

A

ONCE DAILY

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12
Q

Kernicterus is caused by the effects of:

A

Unconjugated bilirubin

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13
Q

All of the following are routinely performed on a cord blood sample except:

A

ANTIBODY SCREEN

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14
Q

A patient had a transfusion reaction to packed red blood cells. The medical laboratory scientist began the laboratory investigation of the transfusion reaction by assembling pre- and post-transfusion specimens and all paperwork and computer printouts. What should he do next?

A

Check for a clerical error(s)

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15
Q

What may be found in the serum of a person who is exhibiting signs of TRALI (transfusion-related acute lung injury)?

A

Antileukocyte antibody

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16
Q

Which type of transfusion reaction occurs in about 1% of all transfusions, results in a temperature rise of 1°C or higher, is associated with blood component transfusion, and is not related to the patient’s medical condition?

A

Febrile nonhemolytic reaction

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17
Q

What would be the result of group A blood given to an O patient?

A

Immediate hemolytic transfusion reaction

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18
Q

What component is most frequently involved with transfusion-associated sepsis?

A

PLATELETS

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19
Q

Fatal transfusion reactions are mostly caused by?

A

CLERICAL ERRORS

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20
Q

Pain at infusion site and hypotension are observed with what type of reaction?

A

Acute hemolytic transfusion reaction

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21
Q

Irradiation of blood is performed to prevent?

A

Transfusion-associated graft-versus-host disease

22
Q

The only presenting sign most often accompanying a delayed hemolytic transfusion reaction is?

A

Unexplained decrease in hemoglobin

23
Q

Which transfusion reaction presents with fever, maculopapular rash, watery diarrhea, abnormal liver function, and pancytopenia?

A

Transfusion-associated graft-versus-host disease

24
Q

Characteristic of iron overload

A

DELAYED, NONIMMUNE COMPLICATION
CHELATING AGENTS ARE USED
MULTIORGAN DAMAGE MAY OCCUR

25
Q

Which of the following tests is useful to confirm that a patient or donor is infected with HCV?

A

RIBA

26
Q

The first retrovirus to be associated with human disease was:

A

HTLV-I

27
Q

What is the most common parasitic complication of transfusion?

A

PLASMODIUM SPECIES

28
Q

The endpoint of the gel test is detected by:

A

AGGLUTINATION

29
Q

The endpoint of the SPRCA test is detected by:

A

Attachment of indicator cells

30
Q

An advantage for both gel and solid-phase technology is:

A

STANDARDIZATION

31
Q

Incubation period for the gel test

A

15 MINS

32
Q

Centrifugation time for the test:

A

10 MINS

33
Q

An important determinant of platelet viability following storage is:

A

PLASMA PH

34
Q

Irradiation of a unit of Red Blood Cells is done to prevent the replication of donor:

A

LYMPHOCYTES

35
Q

The Liley method of predicting the severity of hemolytic disease of the newborn is based on the amniotic fluid:

A

Change in optical density measured to 450 nm

36
Q

Kernicterus is caused by the effects of:

A

Unconjugated bilirubin

37
Q

Blood for intrauterine transfusion should be all of the following, EXCEPT:

A

More than 7 days old

38
Q

RhIG is indicated for:

A

Mothers who are Rh-negative

39
Q

Which of the following is the preferred specimen for the initial compatibility testing in exchange transfusion therapy?

A

Maternal serum

40
Q

Posttransfusion purpura (PTP) is usually caused by:

A

Anti-HPA

41
Q

In a delayed transfusion reaction, the causative antibody is generally too weak to be detected in routine compatibility testing and antibody screening tests, but is typically detectable at what point after transfusion?

A

3 TO 7 DAYS

42
Q

Which of the following transfusion reactions is characterized by high fever, shock, hemoglobinuria, DIC and renal failure?

A

BACTERIAL CONTAMINATION

43
Q

Hemoglobinuria, hypotension and generalized bleeding are symptoms of which of the following transfusion reactions?

A

HEMOLYTIC

44
Q

The MOST COMMON INITIAL clinical manifestation of a hemolytic transfusion reaction is:

A

FEVER

45
Q

Leukocyte-poor red blood cells would most likely be indicated for patients with a history of:

A

Febrile nonhemolytic transfusion reaction

46
Q

Hives and itching are symptoms of which of the following transfusion reactions?

A

ALLERGIC

47
Q

The laboratory assay of brain natriuretic peptide (BNP) may be used to aid in the diagnosis of:

A

TACO

48
Q

The most common isolate found in RBC units

A

Yersinia enterocolitca

49
Q

Organisms most frequently recovered from donated blood and contamination of platelets:

A

Staphylococcus epidermidis, Bacillus cereus

50
Q

Congestive heart failure, severe headache and/or peripheral edema occurring soon after transfusion is indicative of which type of transfusion reaction?

A

Circulatory overload

51
Q

The most frequent transfusion-associated disease complication of blood transfusion is:

A

HEPATITIS

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