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NHPs > BB Ch16 > Flashcards

BB Ch16 Flashcards

1
Q
  1. What does the acronym CITES stand for and what year did it become in effect?
A
  1. Convention on International Trade in Endangered Species of Wild Faunaand Flora; 1975
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2
Q
  1. What Appendix of CITES lists endangered species?
A
  1. Appendix I
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3
Q
  1. What the taxonomic classification of the Lemur? What are the distinguishing characteristics?
A

Suborder Strepsirrhini

(means “wet nose”)

  1. Wet patch around nares
  2. Nocturnal with tapetum lucidum
  3. Toilet claw on 2nd digit of feet (3rd in Aye Ayes)
  4. Tooth comb
  5. Sublingua
  6. Temporal fossa
  7. Epitheliochorial placenta
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4
Q
  1. What is the taxonomy of New World Monkeys? Name three characteristics of New World monkeys distinguishing them from Old World monkeys.
A

Suborder Haplorrhini

Infraorder Simiiformes

Parvorder Platyrrhini

  1. Flat nose
  2. Tympanic bulla
  3. Absence of ischael callosities
  4. Absence of cheek pouches
  5. Prehensile tail (e.g. Capuchin, Squirrel)
  6. No menstruation (except slight in Capuchin)
  7. Require vitamin D3 in diet or UV light
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5
Q
  1. The term neotropical primate is considered to be interchangeable with _________________.
A

New World Monkeys

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6
Q
  1. What is the taxonomic classification of marmosets and tamarins? Squirrel monkeys and Capuchins?
A

All in Parvorder Platyrrhini

Marmosets and tamarins in Family Callitrichidae.

Squirrel monkeys and Capuchins in Family Cebidae.

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7
Q
  1. What is common name, genus and species?
A

Callithrix jacchus jacchus

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8
Q
  1. What is the taxonomic classification of this animal? What are its distinguishing characteristics?
A

Suborder Haplorrhini

Infraorder Tarsiiformes

Genus Tarsius

Shares characteristics of both Strepsirrhini and Simiiformes.

Like Strepsirrhini: nocturnal, grooming claws (3rd digit)

Like Simiiformes: lack tapetum lucidum, closed eye sockets, sex skin tumescence, hemochorial placenta

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9
Q
  1. Taxonomy and characteristics of this animal?
A

Suborder Strepsirrhini

Family Lemuridae

Lemur catta

  1. Wet nose
  2. Nocturnal with tapetum lucidum
  3. Toilet claw
  4. Tooth comb
  5. Sublingua
  6. Epitheliochorial placenta
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10
Q
  1. Which callitrichid used in research is classified as endangered by CITES?
A

Callithrix aurita, C. flaviceps

Sanguinus bicolor, S. geoffroyi, S. leucopus, S. oedipus

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11
Q
  1. What are distinguishing characteristics of Callitrichidae?
A
  1. small size (150-600 g)
  2. claws instead of nails on digits
  3. high frequency of twinning (~80%)
  4. All twins and many singletons are chimeras
  5. Hallux, specialized nail on 1st digit, is opposable
  6. Thumb is not opposable
  7. Only one female in an extended breeding group reproduces
  8. Circumgenital and sternal glands
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12
Q
  1. Which species are listed as endangered:
    a. Howler monkey
    b. Spider monkey
    c. Red-backed squirrel monkey
    d. Uakari monkey
    e. All of the above
A
  1. e, all of the above
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13
Q
  1. What is unusual about dentition in marmosets?
A

Have prominent incisors same length as canines. These allow them to gnaw holes in trees and eat gums and exudates, a staple of their diet.

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14
Q
  1. What are common research uses for this species?
A

Callithrix jacchus, Common Marmoset

Model for Parkinson’s disease

Model fpr allergic encephalomyelitis, which mimics many facets of multiple sclerosis

Models for idiopathic hemochromatosis

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15
Q
  1. What is the concern about feeding neonatal mice to marmosets and tamarins as a supplemental protein source?
A

Health status of mice must be known. Lymphocytic choriomeningitis virus can be transmitted to marmosets and tamarins.

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16
Q
  1. What is the family, genus, and species? What are some uniques characteristics of this genus?
A

family Cebidae

Aotus lemurinus griseimemra

Gray-necked owl monkey

  1. Small (~1 kg)
  2. Nocturnal but no tapetum, and retain retinal fovea, have both rods and cones (cones decreased)
  3. Low metabolic rate (18-24% below predicted value for weight)
  4. All owl monkeys belong to Aotus but variation in chromosome number (46-56)
  5. Within A. l. griseimembra 2n is 52-54
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17
Q
  1. When does menarche occur in the macaque?
A
  1. Menarche (onset of menstruation) occurs at approximately 2 years
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18
Q
  1. Rhesus menstrual cycle lasts ________ days.
A

28 days

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19
Q
  1. How is pregnancy determined in monkeys?
A
  1. ultrasonography or palpation
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20
Q
  1. What is the range of gestation for macaques?
A

161-175 days

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21
Q
  1. What is the range of gestation for Callitrichids?
A

140-150 days

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22
Q
  1. What is the family, genus and species? What some characteristics of this genus?
A

family Cebidae

Saimiri sciureus

Note high Gothic arch. Could also be S. oerstedii or S. ustus. Precise identification requires both phenotypic and karyotypic examination.

  1. Body weight < 1 kg
  2. Males 25-30% larger than females
  3. Males and females undergo seasonal reproductive changes, from infertility or anestrus to fertility, with corresponding low and high sex hormone levels
  4. Males undergo fatting and testes enlargement
  5. Have free/unbound cortisol ~100X that of humans or OWPs
  6. Naturally occurring atherosclerosis
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23
Q
  1. What is the ovarian cycle length in the common marmoset?
A

28.6-30.1 days

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24
Q
  1. Describe the chromosome number in squirrel monkeys.
A

2n = 44

Vary in number of acrocentric chromosomes (5-7), thought to be due to pericentric inversions.

Karyotyping is critically important because:

  1. Species and subspecies vary in susceptibility to both naturally and experimentally-induced disease.
  2. Interbreeding between different species or subspecies can lead to heterozygosity for pericentric inversions leading to non-viable gametes due to meiotic cross-over events at the inversion. Up to 50% of hybrid squirrel monkey conceptions could be non-viable.
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25
Q
  1. Describe husbandry and housing for this species.
A

Cotton-topped tamarin (endangered)

Sanguinus oedipus

  1. This species will become metabolically stressed at ambient temperatures less than 89 F (32 C) and can lead to chronic colitis
  2. Marmosets and tamarins usually housed in pairs or small family groups
  3. Narrow, high cages preferable to larger floor space with less height since callitrichids spend little time on the floor.
  4. Multiple feeding stations for callitrichids are needed and should be above floor if housing > 1 animal per cage. Food guarding can contribute to wasting syndrome.
  5. Scent marking important. Have wood or fiber objects in cage sanitized on alternate schedule than cage.
  6. Callitrichids need flat surface for sleeping, preferably a nest box, high in cage.
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26
Q
  1. New World monkeys require a dietary supplement of what vitamin?
A

Vitamin D3 (or irradiation w/ UV light) and vitamin C

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27
Q
  1. Squirrel monkeys have a high requirement of ________ and differences of this vitamin in pregnant females is associated w/megaloblastic anemia, low birth weights & stillbirths.
A
  1. Folic Acid
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28
Q
  1. T/F Squirrel monkeys menstruate.
A

False; they’re seasonally polyestrous

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29
Q
  1. What cyclic changes do male squirrel monkeys undergo?
A
  1. Becomes heavier (“fatting”) primarily in torso prior to and during breeding seasons (March to May in Northern Hemisphere) assoc. w/ increased testes size, spermatogenesis & increased plasma testosterone concentration.
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30
Q
  1. The ability of ________ to cause malignant lymphoma or regressing lymphoreticular hyperplasia in Callitrichidae is an important biological link between infectious mononucleosis and neoplastic disease associated with________ in man.
A
  1. Ebstein Barr Virus (EBV), lymphoma
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31
Q
  1. How many days is the owl monkeys ovarian/estrus cycle?
A
  1. 15-16 days
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32
Q
  1. When is puberty in owl monkeys in males? In females?
A

Between 300-400 days in both sexes.

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33
Q
  1. Which NHP spepcies are used for malaria research?
A

Aotus spp. (owl monkeys)

Saimiri spp. (squirrel monkeys)

Chimpanzees

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34
Q
  1. Which NHP’S species requires both phenotypic and karyotypic examination for the production of viable gametes?
A
  1. Squirrel monkey
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35
Q
  1. T/F Squirrel monkeys are seasonal breeders and have a narrow timespan for conception.
A

True

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36
Q
  1. T/F Squirrel monkeys have a high incidence of dystocia due to the fetal-to-dam size.
A

True

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37
Q
  1. Which species has little body fat, high metabolic rate and need 80 F ambient temperatures and thermoneutral perches to prevent hypothermia?
A

Squirrel monkey

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38
Q
  1. This species is ideally suited for what type of malaria research?
A

Note Roman arches. Saimiri boliviensis

If presume S. b. bloiviensis subspecies, then best for Plasmodium falciparum, because develop lesions and signs similar to humans.

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39
Q
  1. Which species is prone to pelvic organ prolapse (POP) and is used for a human model?
A

Squirrel monkey

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40
Q
  1. Match the genus with the species:
    M. arctoides __________________
    M. fascicularis __________________
    M. fuscata __________________
    M. mulatta __________________
    M. nemestrina __________________
    M. radiata __________________
A

25.

M. arctoides (Stump-tailed)

M. fascicularis (cynomologous)

M. fuscata (Japanese)

M. mulatta (rhesus)

M. nemistrina (Pig-tailed)

M. radiata (Bonnet)

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41
Q
  1. T/F Cynomolgus monkeys are not seasonal and are capable of breeding throughout the year.
A

True

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42
Q
  1. Which species has a seasonal breeding period in the Northern Hemisphere?
    a. Chimpanzee
    b. Cynomolgus monkey
    c. Rhesus
    d. Baboon
A

c

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43
Q
  1. When does ovulation occur in baboons?
    a. 1-2 days prior to deturgescence
    b. the day of deturgescence
    c. 1-2 days after deturgescence
A
  1. a. 1-2 days prior to deturgescence
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44
Q
  1. What is the gestation period of baboons?
A
  1. 164-186 days
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45
Q
  1. Which species has been used the most for organ transplantation?
A
  1. baboon
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46
Q
  1. What is the gestational period of chimpanzees?
A
  1. 227-235 days
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47
Q
  1. T/F Marmosets of the same sex will fight if housed together.
A

True

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48
Q
  1. Why is UV light needed in breeding colonies of callitrichids?
A
  1. Produces Vit D3 by activating 7, dehydrocholesterol which essential to NWM Calcium metabolism and prevents cage paralysis (osteodystrophia fibrosa)
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49
Q
  1. What is a common problem in callitrichids due to puncture wounds, chronic cauditis or bitten fingers?
A
  1. Osteomyelitis
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50
Q
  1. T/F Limited food access can be a factor contributing to “Wasting Marmoset Syndrome.”
A

True

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51
Q
  1. When a Rhesus is Specific Pathogens Free (SPF), what diseases is the monkey free of?
A
  1. CHV-1, SIV, SRV, TB
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52
Q
  1. Marmosets and tamatins have a dietary requirement for
    a. Vitamin D2 and calcium
    b. Vitamin D3 and ascorbic acid
    c. Vitamin C
    d. Vitamin E
A
  1. b - Vitamin D3 and ascorbic acid
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53
Q
  1. Squirrel monkeys are currently available from which two countries but in limited supply?
    a. Bolivia and Mexico
    b. Peru and Guyana
    c. Venezuela and Ecuador
A
  1. b, Peru and Guyana
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54
Q
  1. Which species does not require Vitamin D3 in their diet?
    a. Tamarin
    b. Squirrel monkey
    c. Owl monkey
    d. Rhesus monkey
A
  1. d, rhesus
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55
Q
  1. Provide the size range, example species, minimum required floor space, and minimum required cage height for Group 2 NHPs.
A

1-3 kg, owl monkey, 3.0 ft2, 30 inches

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56
Q
  1. What year did the amendment to the Animal Welfare Act require “environmental enhancement?”
    a. 1976
    b. 1985
    c. 1992
    d. 1999
A
  1. b, 1985
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57
Q
  1. What is the proper terminology for the Herpes B virus?
A

Macacine herpesvirus 1

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58
Q
  1. Provide the size range, example species, minimum required floor space, and minimum required cage height for Group 1 NHPs.
A

Group 1 (up to 1 kg, commom marmoset): 1.6 ft2 and 20 inches high

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59
Q
  1. Which nonhuman primate diseases are considered zoonotic?
    a. Measles
    b. TB
    c. Campylobacter
    d. All of the above
A

d

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60
Q
  1. What is preventative treatment of “exposure” to CHV-1 according to the CDC?
    a. Septisol wash
    b. Soak wound in 10% bleach solution for 15 minutes
    c. Baseline blood samples for monkey and person exposed
    d. All of the above
A

d, all of the above

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61
Q
  1. According to the ILAR guide, indoor facilities for nonhuman primates should be kept in a temperature range of
    a. 60-80 F
    b. 64-84F
    c. 50-90F
    d. 65-75F
A
  1. b, 64-84 F
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62
Q
  1. In indoor facilities holding Old World monkeys the humidity range should be
    a. 30-70%
    b. 50-100%
    c. 0-50%
A

a. 30-70%

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63
Q
  1. T/F ILAR recommends that lighting of indoor facilities for Old World monkeys should have an 8 hour light, 16 hour dark diurnal cycle using a time-controlled lighting system.
A
  1. F, 12 hour light-12 hour dark
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64
Q
  1. Ideally, the quarantine period for newly acquired nonhuman primates should be _____ days.
    a. 30
    b. 60
    c. 90
A
  1. c, 90 days
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65
Q
  1. A safe maximum blood draw of total blood volume for nonhuman primates is:
    a. 5%
    b. 10%
    c. 15%
    d. 20%
66
Q
  1. In nonhuman primates, cerebrospinal fluid can be collected in the following anatomic locations:
    a. Cisterna magna
    b. Lumbar intervertebral space
    c. Both a and b
67
Q
  1. The preferred site to obtain a bone marrow aspirate from a nonhuman primate is:
    a. Iliac crest
    b. Rib
    c. Proximal humerus
A

a, iliac crest

68
Q
  1. T/F Intraosseous infusion of IV fluids may be used in severely debilitated hypotensive monkeys when venous access is limited.
69
Q
  1. T/F The primary cause of morbidity and mortality in Old World monkeys is enteric disease.
70
Q
  1. Old World monkeys can be chronic carriers of what enteric pathogens:
    a. Salmonella
    b. Shigella
    c. Campylobacter
A
  1. b Shigella
71
Q
  1. What organism causes dysentery in macaques?
A

Shigella spp

72
Q
  1. What is the most common enteric pathogen isolated in nonhuman primates?
    a. Campylobacter spp.
    b. Shigella
    c. Salmonella
    d. Yersinia
A
  1. a, Campylobacter spp.
73
Q
  1. Which enteric bacteria causes a triad of lesions at necropsy mulfocal hepatic and splenic necrosis or abscess formation, mesenteric lymphadenopathy and ulcerative enterocolitis?
A
  1. Yersinia spp.
74
Q
  1. Which pathogen is the most common cause of respiratory disease in chimpanzees?
A
  1. Streptococcus pneumoniae
75
Q
  1. Which organism is very prevalent that can cause pneumonia, septicemia, meningitis and high mortality in tamarins and squirrel monkeys?
    a. Nocardia spp.
    b. Klebsiella pneumoniae
    c. Staph arreus
    d. Hemophilus
A
  1. b, Klebsiella pneumoniae
76
Q
  1. Pasteurella multocida can case which of the following in squirrel monkeys and owl monkeys?
    a. Pneumonia
    b. Meningitis
    c. Pleuritis
    d. All of the above
77
Q
  1. Which filamentous bacterial organism is very commonly isolated in nonhuman primates and is characterized by pyogranulomas with sulfur granules?
A
  1. Nocardia spp.
78
Q
  1. Tuberculosis in nonhuman primates is caused by:
    a. Mycobacterium tuberculosis
    b. M. bovis
    c. M. africanum
    d. All of the above
A
  1. d, all of the above
79
Q
  1. What nonhuman primate species have been diagnosed with naturally acquired Leprosy?
    a. Sooty mangaby
    b. Cerocebus atys
    c. Chimpanzee
    d. All of the above
80
Q
  1. Which bacterial infection in nonhuman primates can incubate for more than 10 years and is sensitive to treatment with rifampin, dapsone and clofazimine?
A
  1. Mycobacterium leprae
81
Q
  1. The most common contaminant indwelling catheters in nonhuman primates is:
    a. Pseudomonas
    b. Staphococcus
    c. E. coli
    d. Yersinia
A
  1. b. Staphylococcus
82
Q

Name the fungal organism that causes San Quajin “Valley Fever.”14. What mycotic organism causes intestitial pneuWhat mycotic organism causes intestitial pneumonia and stains positive with silver or periodic acid-Schiff?monia and stains positive with silver or periodic acid-Schiff?

A
  1. Pneumocystis
83
Q
  1. Name the fungal organism that causes San Joachin “Valley Fever.”
    a. Coccidioides immitis
    b. Nocardua
    c. Histoplasmosis
    d. Cryptococcus
A
  1. a, Coccidioides immitis
84
Q
  1. The organism reported to an infection cause papules and pustules of the skin contacting the ground in baboons is:
    a. Histoplasma capsulatum
    b. Coccidiodes immitis
    c. Candida albiuns
    d. Cryptococcus neoformens
A
  1. a, Histoplasma capsulatum
85
Q
  1. A synonym for Cercopithecine Herpes virus 2 is
    a. Simian Agent 8
    b. Herpes papionus
    c. Herpes simiae
    d. a and b
A
  1. d, both a. SA8 and b. Herpes papionus
86
Q
  1. Which gamma herpes virus has been associated with lymphoma in aberrant nonhuman primates?
A
  1. Ebstein Barr Virus (EBV)
87
Q
  1. T/F The Ebola-Reston virus outbreak in cynomolgus macaques in 1989-1990 was distinguished from simian hemorrhagic fever virus histologically.
88
Q
  1. T/F Simian hemorrhagic fever virus causes fatal hemorrhagic disease in aberrant Asian macaques.
89
Q
  1. The reported reservoirs of simian hemorrhagic fever virus are:
    a. Patas
    b. African green monkey
    c. Baboon
    d. All of the above
A

d. All of the above

90
Q
  1. T/F Quarantine of imported primates is limited to laboratories with BSL-3 containment facilities.
91
Q
  1. T/F Immunization of nonhuman primates with MCV vaccine can cause immunosuppression that interferes with TB testing.
92
Q
  1. T/F Simian retrovirus type D are the primary cause of viral-induced immunodeficiency in captive macaques and is associated with retroperitonal fibromatosis.
93
Q
  1. Naturally occurring cases of Hepatitis A virus have been described in which species?
    a. Chimpanzee
    b. Owl monkey
    c. African grey monkey
    d. Cynomologus monkey
    e. All of the above
94
Q
  1. What is the reservoir of the encephalomycarditis virus?
A

wild rodents

95
Q
  1. Glossitis, esophagitis and occasionally gastritis caused by ________ are common in debilitated animals.
96
Q
  1. Trypanosomes (“T. cruzi”) are common/rare in Callitrichids?
97
Q
  1. What GI zoonotic protozoa is common in Callitrichids? What pulmonary protozoa is common?
A
  1. Entamoeba histolytica, Pneumocystis carinii
98
Q
  1. The most important and pathogenic worms in Callitrichids are what? Intermediate host?
A
  1. Acanthocephalan worms (Prosthenorchas elegans and P. spirula), but host is cockroach and there have been colony bred episodes of P.elegans and
    P.spirula infections due to local roaches.
99
Q
  1. Trematodes in Callitrichids are numerous/few and cause many/few clinical signs? Where are they located?
A
  1. Numerous, few; S.I. bile ducts, lymphatics, mesenteric lymph nodes
100
Q
  1. T/F Viral diseases appear to be rare in callitrichids.
101
Q
  1. Which viral diseases commonly occur in callitrichids? What are the clinical signs?
A
  1. Influenza A-2, Parainfluenza 2 + 3 Reovirus 3, basically asymptomatic
102
Q
  1. ________ virus & “Herpes tamarinus” infection were uniformly fatal in callitrichids.
103
Q
  1. What is most important Herpesvirus in callitrichids?
A
  1. Herpesvirus tamarinus (platyrrhinae)
104
Q
  1. What are the clinical signs of Samarine herpesvirus 1 (Herpes T) in NWM?
A

36.

Rhinitis, ulcers from lips thru GI, hyperesthesia.

Path: Focal necrosis of liver + other visceral organs.

INICB’s, Hemorrhage in the adrenal cortex.

Pneumonia.

Encephalitis w/perivascular cuffing.

105
Q
  1. What species is the natural host of Samarine herpesvirus 1 (Herpes T)?
A
  1. Squirrel monkeys
106
Q
  1. Does Herpesvirus simplex (human) affect NWM?
107
Q
  1. Feral callitrichids are invariably infected w/thorny-headed worms which have what as intermediate host?
108
Q
  1. The most common single cause of morbidity in most callitrichid colonies is what?
A
  1. Diarrheal disease, especially in tamarins. Cause of diarrhea is usually unknown.

Histology: Atony, megacolon, crypt atrophy, cellular
infiltration of mucosa, crypt abcesses, hyperplasia & cystic crypts, chronic colitis

109
Q
  1. T/F Shigella is more commonly is subacute to chronic diarrhea w/carriers.
110
Q
  1. Salmonella infection is found in what part of the intestinal tract?
A
  1. Cecum and colon
111
Q
  1. What is the primary cause of morbidity and mortality of Old World NHP’s?
112
Q
  1. What GI sporozoa is associated with AIDS in man and causes diarrhea in NHP’s?
A
  1. Cryptosporidium
113
Q
  1. What nematode can seriously affect NHP’s? It has 3 pathways: ingestion of larva, skin penetration and autoinfection.
A
  1. Strongyloides fullebroni
114
Q
  1. Name a common saprophyte of skin, GI & Repro Systems that can cause raised white plaques over dorsum of tongue, oral cavity, esophagus when an
    animal has been on longterm antibiotics.
A
  1. Candida albicans
115
Q
  1. What enteric protozoa makes pathogneumonic “flasklike” amebic intestinal lesions in New World monkeys?
A
  1. Entamoeba histolytica
116
Q
  1. The larval form of what cestode develops into hydatid cysts.
A
  1. Echinococcus granulosus
117
Q
  1. Does Measles cause higher mortality in New or Old World monkeys?
A
  1. New World Monkeys
118
Q
  1. What type of pneumonia occurs with Measles in NHP’s?
A
  1. Giant cell pneumonia.
119
Q
  1. What test does measles interfere with?
A
  1. False negative (?) reaction on TB tests
120
Q
  1. Are NWM carriers of the Herpes Simiae (B Virus)?
121
Q
  1. What NHP’s are most susceptible to SHF?
A
  1. Macaques most susceptible.
122
Q
  1. What is pathogonomic lesion of SHF?
A
  1. Hemorrhagic necrosis of proximal duodenum and stops abruptly at pyloris
123
Q
  1. What mosquito born viral disease is rarely severe in African NHPs but is severe in Asian macaques?
A
  1. Yellow fever
124
Q
  1. Name 3 Poxviruses that affect macaques.
A
  1. Monkeypox, Yaba virus, Tanapox
125
Q
  1. What is the primary bacterial organisms that causes pneumonia in chimpanzees?
A
  1. Streptococcus pneumoniae
126
Q
  1. What is primary route of infection for TB?
A
  1. Inhalation of organism
127
Q
  1. The intradermal TB test detects what type of hypersensitivity to tuberculin?
A
  1. Delayed Hypersensitivity
128
Q
  1. How many negative TB tests are required in quarantine?
A
  1. 2 negative tests over 30 days (?)
129
Q
  1. How many units of mammalian Old Tuberculin are injected ID?
A

1500 units

130
Q
  1. How often are TB tests read?
A
  1. Read at 24, 48 & 72 hrs
131
Q
  1. Which Herpesvirus produces a highly fatal disease in vervet monkeys w/vesicular lesions and fatal necrosis in parenchymal organs?
132
Q
  1. T/F Hepatitis A/B of man, transmitted fecal-oral, infects chimps w/few clinical signs
133
Q
  1. What zoonotic disease in NHP’s is caused by an Orthopox Virus similar to smallpox in man?
134
Q
  1. What organism is commonly isolated from NHP’s w/ bloat?
135
Q
  1. Infection of laryngeal air sacs is common in ________ species.
A
  1. Aotus, Chimpanzee
136
Q
  1. Owl monkeys are used for which two malaria parasites species?
A
  1. P. falciparum & P. vivax
137
Q
  1. All clinical and pathologic manifestations of malarial infections are due to the erythrocytic/hepatic phase.
A
  1. erythrocytic
138
Q
  1. Which helminths are most common in NWM?
139
Q
  1. What saprophyte is aerobic, gram pos, partially acid fast, causes a granulomatous lesion and can be misdiagnosed for TB?
A
  1. Nocardia asteroides
140
Q
  1. Dermatophytosis of NHP’s is mostly caused by what?
A
  1. Microsporum canis
141
Q

Provide the size range, example species, minimum required floor space, and minimum required cage height for Group 3 NHPs.

A

3-10 kg (macaque), 4.3 ft2, 30 in

142
Q

Provide the size range, example species, minimum required floor space, and minimum required cage height for Group 4 NHPs.

A

10-15 kg (female baboon), 6.0 ft2, 32 in

143
Q

Provide the size range, example species, minimum required floor space, and minimum required cage height for Group 5 NHPs.

A

15-25 kg (male baboon), 8.0 ft2, 36 in

144
Q

Provide the size range, example species, minimum required floor space, and minimum required cage height for Group 6 NHPs.

A

over 25 kg (chimpanzee), 25.1 ft2, 84 in

145
Q

What is the average weight range of African Green Monkeys?

A

Males 5.5 kg

Females 4.1 kg

146
Q

What is the taxonomy and CITES statuses of African green monkeys?

A

Family Cercopithecidae

Genus Chlorocebus

CITES Appenix II

147
Q

What is unique about African green monkey male genitals?

A

Blue scrotum, red penis

148
Q

What is the lifespan of AGM?

A

11-13 years in the wild

up to 25 in captivity

149
Q

What is the dental formula of Old World primates?

A

I 2/2, C1/1, P 2/2, M 3/3

150
Q

How long is the menstruation cycle of female AGM?

A

30-32 days

151
Q

What is the gestation length of AGMs?

A

163-165 days

152
Q

What are vero cells?

A

cell line derived from African Green monkey kidney epitheluim

153
Q

Taxonomy and CITES status of the chimpanzee

A

Family Hominidae

Genus Pan

Species troglodytes

CITES Appendix I

154
Q

Key research uses for chimpanzee

A

Hepatits A, B, and C

Ebola virus vaccine

Malaria vaccine

155
Q

Provide the timeline for increasing limits on the use of chimpanzees in research

A

1995: NIH moratorium on breeding NIH-owned or supported chimps
2013: NIH accepts recommendations for limiting use of chimps in biomedical and behavioral research to 50 individuals.

156
Q

Diploid number for the chimpanzee

157
Q

Chimpanzee life span

A

15-19 years in the wild

40-50 years in captivity

158
Q

Chimpanzee weight range

A

males 40-60 kg

females 32-47 kg

159
Q

Gestation length of champanzees

A

7.5-8 months

160
Q

menstrual cycle length of chimpanzees

161
Q

What are the housing requirements for chimpanzees involved in NIH-supported research?

A

social groups of no fewer than 7 individuals

at least 20 feet of available vertical space

maximum density of 250 ft2 per animal

NHPs (5 decks)

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