BB Flashcards
Single blood donation to multiple patients:
- COMPONENT PREPARATION
- RBCs, platelets, fresh-frozen plasma, cryoprecipitate, plasma derivatives
EQUIPMENT IN THE COMPONENT MANUFACTURING LABORATORY:
1. CENTRIFUGES
- spin a maximum of ___ at once
- ___; ___ can be changed based on ___
A. HARD SPIN
- depends on ___
B. SOFT SPIN
- not remove ___ out of ___
- 6-12 units of WB
- programmable speed (RPM), time settings, components
- length / duration & speed
- plasma, RBC
AABB-RECOMMENDED CENTRIFUGE CONDITIONS
Components Prepared - Centrifuge Conditions
RBCs + Plasma:
RBCs + Platelet-Rich Plasma:
Harvesting Platelets / Cryoprecipitate from Plasma:
RBCs + Plasma: 5,000 x g, 5 minutes
RBCs + Platelet-Rich Plasma: 2,000 x g, 3 minutes
Harvesting Platelets / Cryoprecipitate from Plasma: 5,000 x g, 7 minutes
EQUIPMENT IN COMPONENT MANUFACTURING LABORATORY:
2. PLASMA EXPRESSORS
- apply ___ to the ___
- blood components flow ___ by ___
- pressure, blood bag
- flow from one bag to another, integrated tubing system
EQUIPMENT IN COMPONENT MANUFACTURING LABORATORY:
3. TUBING SEALERS
- tubing that connects blood bags:
PVC (POLYVINYL CHLORIDE) - resistant to damage
EQUIPMENT IN COMPONENT MANUFACTURING LABORATORY:
4. STERILE CONNECTION DEVICES (SDCs)
- ___ connected via ___ w/o ___
- each piece of tubing is placed in a ___ and ___
- 2 separate blood bags, PVC tubing, breaching the integrity of either container
- channel, clamped
EQUIPMENT IN THE COMPONENT MANUFACTURING LABORATORY:
5. STORAGE DEVICES
- carefully selected and validated; ___
- temp must be ___, ___ at least ___
- ___ if ___
- FDA-regulated storage temperatures
- continuously monitored, recorded, EVERY 4 HOURS
- alert, unacceptable temperature
EQUIPMENT IN THE COMPONENT MANUFACTURING LABORATORY:
6. QUADRUPLE BAG
- ___ depending on the ___
MOTHER BAG - ___ (___)
SATELLITE BAGS (___) - ___ —> ___ will be transferred ___
- triple bags, component that will be produced
- primary component (whole blood)
- 2, expression, separate component, directly
BLOOD COMPONENTS:
OXYGEN-CARRYING PRODUCTS
THE WHOLE BLOOD AND ITS COMPONENTS:
WHOLE BLOOD
- ___
- ___ - ___
- mother / primary component
- unmodified - directly from the donor
WHOLE BLOOD
Indications:
Indications:
Active bleeding
Hemorrhagic shock
Exchange Transfusion
Both oxygen-carrying capacity and volume expansion required
WHOLE BLOOD
Shelf-life:
21 DAYS:
35 DAYS:
42 DAYS:
WHOLE BLOOD
Shelf-life:
21 DAYS: CPD, ACD, CP2D
35 DAYS: CPD-A1
42 DAYS: CPD-AS-1 (Adsol), AS/3 (Nutricel), AS-5 (Optisol)
WHOLE BLOOD
Shelf-life:
___: CPD, ACD, CP2D
___: CPD-A1
___: CPD-AS-1 (Adsol), AS/3 (Nutricel), AS-5 (Optisol)
21 DAYS: CPD, ACD, CP2D
35 DAYS: CPD-A1
42 DAYS: CPD-AS-1 (Adsol), AS/3 (Nutricel), AS-5 (Optisol)
WHOLE BLOOD
Characteristics:
* WBCs and Platelets - no longer viable after ____
* LABILE FACTORS (FACTORS ___ & ___) - significant ___ AFTER ___
- 24 HOURS
- V & VIII, decrease, 2 DAYS
WHOLE BLOOD
Storage Temp:
1-6 degC (monitored temp)