Basics

Question 1

What are isoenzymes ?

Answer 1

They are physically distinct forms of the same enzyme that catalyze the same reaction but differ structurally immunologically and electrophoretically

Question 2

Subunits are same, protein is a ————- represented by a single gene

Answer 2

Homo multimer

Question 3

Subunits are different, protein is a ——- produced by different genes

Answer 3

Hetero multimeter

Question 4

What are true isoenzymes

Answer 4

They may be products of different genes (more than one locus)

Question 5

An example of true isoenzymes are

Answer 5

Salivary and pancreatic amylase

Question 6

Lactate dehydrogenase has —- isoenzymes seen in all persons

Answer 6

5

Question 7

What are allozymes?

Answer 7

The same locus of a gene may have different alleles. Such alleles isoenzymes are allozymes

Question 8

An example of allozymes is

Answer 8

400 forms of glucose 6 phosphate dehydrogenase

Question 9

G6PD allozymes are produced by the same locus on —— chromosome

Answer 9

X

Question 10

Molecular heterogeneity of enzyme produced after protein is synthesized ie post translational modification. These are called

Answer 10

Isoforms

Question 11

An example of isoform is

Answer 11

Sialic acid content in alkaline phosphate isoenzymes