Basic Decision-Making Flashcards
Lobotomies
- come from term love, and to cut or slice
- clinical treatment for mental illness -> depression / schizophrenia
- pioneered by Antonia Moniz who received a Nobel prize for this work
how did lobotomies usually work?
holes drilled into the side of people’s head, alcohol was poured in and this would scramble their circuits providing a full frontal lobotomy
* then improved to ice-picking: tapped into the orbit of someone’s eye socket (trans-orbit), moved around to sever and scramble the brain tissue
by 1951, how many lobotomies had been conducted in the US alone?
20,000
how many of the people receiving lobotomies were women?
60%
Rosemary Kennedy
had a lobotomy at 23 y/o and her mental capacity limited to 2 y/o
when did lobotomies fall out of use?
by the 1970s
effects of lobotomies were unpredicted but generally encompassed ‘higher mental functions’. Lobotomies would affect:
- Judgment.
- Future planning.
- Social awareness.
- Creativity.
- Ability to relate emotionally to other people.
how did nurses and doctors report their patients to turn out like?
Dull, apathetic, listless, without drive or initiative, flat, lethargic, placid and unconcerned, childlike, docile, needing pushing, passive, lacking in spontaneity, without aim or purpose, preoccupied and dependent
what does ‘neocortex’ mean?
new bark
what’s executive control for? -> five types of situation (Norman & Shallice, 1980)
- When we need to plan (or decision-making)
- When we need to troubleshoot problems (/problem solving).
- Dealing with novel or unplanned situations.
- Overcoming a habitual response.
- Dealing with danger or difficulty.
what is the homunculus problem?
Explaining volitional acts (relating to the use of one’s will) without assuming a cognitive process that is itself volitional (i.e. a man within a man)
What are aspects of executive control?
Attention -> Cognitive flexibility -> Monitoring
* Planning.
* Time management.
* Motivation.
* Organization.
* Working Memory.
* Inhibition of a response.
* Initiation.
* Goal orientation.
* Task switching (alternating between different programs).
Remember quite a lot of executive control remains subconsciously, which is an important distinction
what is executive control?
collection of brain processing that guide your thought and behaviour
where is the executive control primarily located?
the prefrontal cortex but does involve other networks and sub-cortical structures to
* As a result, we get these high order cognitive skills that basically enable your independent, purposeful goal directed behaviour
what were certain people lacking when they had a lobotomy?
high order cognitive skills that basically enable your independent, purposeful goal directed behaviour
what is the prefrontal cortex involved in?
attention, memory, task competition and engagement
what happens when the prefrontal cortex is damaged?
found observed behaviour in animals was disruptive -> apathetic, poor memory, issues with associative skills and learning, particularly negative learning and reinforcement, trouble with engaging in certain steps to reach a goal and disrupted social connections particularly with their caregiver
According to Broadmann (1909), the PFC accounts for % in humans
29% (1/3 of our cortical service in humans is part of our PFC, we have massive neocortex and takes up 20% of your resting energy (metabolism) will be allocated to aspects of the brain). - we are social animals, living a social context and have adaptively evolved and can transmit culture, whole set of learning which gets passed on which has a massive adaptive advantage)
According to Broadmann (1909), the PFC accounts for % in chimps
17%
According to Broadmann (1909), the PFC accounts for % in macaque
11.5%
According to Broadmann (1909), the PFC accounts for % in cats
3.5%
what is a distinctive human and primate feature?
greatly enlarged PFC
The PFC is highly interconnected and bidirectional. what does it mean to be bidirectional?
information is being communicated back and forth
what does tractography show about PFC interconnectivity?
3D modelling technique which shows neural pathways goes throughout our brain. Both ipsolateral (same hemisphere) and across the corpus callosum.
* shorter connections are grey matter, and longer connections are white matter but both of these things are connecting different brain regions and allowing the brain to communicate with itself - gives impression it is a coordinating hub
* aspects of the previous frontal cortex, and its interconnectivity are very important for it’s role
in the prefrontal cortex, we’ll usually activate multiple aspects of our executive control. what are these areas?
- mid-dorsolateral PFC
- Frontopolar Cortex
- Premotor Cortex
- Posterior Lateral PFC
what is the mid-dorsolateral PFC responsible for?
- task switching, categorisation of sequences, complex stimulus-response contingencies
what is the premotor cortex responsible for?
response selection, execution of simple actions, rule matching
what is the posterior lateral PFC responsible for?
selection of sequences of responses, categorisation of sequence, rule learning
what is the frontopolar cortex responsible for?
tracking goals and subgoals, relational integration, information-seeking behaviour
what is the dorsolateral PFC responsible for? (an aspect of executive control)
circuits play a role in memory, attention, goal setting, motivation.
what is the lateral frontal polar cortex responsible for? (an aspect of executive control)
subjective self, autonoetic consciousness (form of mental time travel which allows you to place yourself in the past and stimulate aspects of your future behaviour), honour and theory of mind
what is the ventrolateral PFC responsible for? (an aspect of executive control)
social and emotional functions, self-regulation
* certain forms of emotional learning
^ future forward we get, the more abstract the qualities they provide
Dorsal
towards the top
Ventral
towards the bottom
Anterior Rostral
towards the front
posterior
towards the back