BASIC CONCEPTS ON LAB BIOSAFETY AND BIOSECURITY Flashcards
origins of biosafety is rooted in the?
US Biological Weapons Program (1943)
an inherent component of biological weapons development
Biosafety
early progenitors to the nearly ubiquitous engineered control
ventilated cabinet
are possible sources of Laboratory Acquired Infections (LAI)
pathogenic microorganisms
Laboratory biosafety and biosecurity traces its history in _____and _____
North America and Western Europe.
who ordered the US Biological Weapons Program
US President Franklin Roosevelt
the first scientific director of Camp Detrick.
Ira L. Baldwin
1969
President Richard Nixon terminated the US Biological Weapons program.
developed specific technical solutions such as Class III Safety Cabinets and Laminar flow hoods to address specific risks.
Newell A. Johnson (in year 1943)
establishing biological weapons program for defensive purposes
Camp Detrick (Fort Detrick) → Year 1943
In 1907 and 1908, _________described the use of _______ to prevent _______.
Arnold Wedum; Mechanical Pipettors; laboratory-acquired infections.
In 1909, a pharmaceutical company in __________ developed a ______ to prevent infection from mycobacterium tuberculosis.
Pennsylvania; ventilated cabinet
in this year, Mortality and morbidity increased due to small pox
1967
in this year, Wedum and Microbiologist Morton Reitman, analyzed multiple epidemiological studies of laboratory-based outbreaks
1966
in this year US President Richard Nixon terminated the US Biological Weapons Program
1969
introduced the concept of establishing ascending levels of containment associated with risks in handling groups of infectious microorganisms that present similar characteristics
“Classification of Etiological Agents on the Basis of Hazard”
CDC
Centers for Disease Control and Prevention in the US
in this year, CDC published “Classification of Etiological Agents o the Basis of Hazard”
1974
SRCVB VECTOR
State Research Center of Virology and Biotechnology VECTOR in Russia
in this year, the NIH of the United States published “NIH Guidelines for Research Involving Recombinant DNA Molecules”
1976
explained microbiological practices, equipment, and facility necessarily corresponding to four (4) ascending levels of physical containment
“NIH Guidelines for Research Involving Recombinant DNA Molecules”
NIH
National Institutes of Health
WHO’s third edition of Laboratory Biosafety Manual was published on what year
1983
who jointly published the Biosafety in Microbiological and Biomedical Laboratories in 1984
CDC and NIH
director of Industrial Health and Safety at the US Army Biological Research Laboratories
one of the pioneers of Biosafety that provided the foundation for evaluating the risk of handling infectious microorganism.
(1944)
Arnold Wedum
1996
US Government enacted the Select Agent Regulations to monitor the transfer of a select list of biological agents.
AMERITHRAX → “anthrax attacks”
2001
materials that pose the greatest risk of deliberate misuse, and the remaining select agents.
Tier 1 Agents
in this year, the Select Agent Regulations sought to address the creation of two tiers of select agents.
2012