Basic Components of the Nervous System ---- NEUROGLIAL CELLS--- Matching Flashcards
NEUROGLIAL CELLS are also called….
Glial Cells
How many NEUROGLIAL CELLS are in the body compared to neurons?
More numerous (900 billion) than neurons (100 billion) in the body
What are the Differences from Neurons? (3)
1) Do not produce or conduct action potentials 2) Support neurons in various ways (depending on type) 3) Capable of mitosis throughout their life, unlike neurons—major cause of brain cancer
*most numerous, up to 90% of some brain areas
Astrocytes
Help produce and circulate (using cilia) cerebrospinal fluid (CSF) through the subarachnoid space surrounding the brain. Found in hollow brain cavities called VENTRICLES.
Ependymal Cells
Form scar tissue in any areas of brain where neurons have died
Astrocytes
Two types of neuroglial cells form myelin sheaths
Oligodendrocytes Schwann Cells/Neurolemmocytes
Form myelin sheaths around many neuron axons located in the CNS (brain and spinal cord).
Oligodendrocytes
Form a myelin sheath around a single neuron axon in the PNS (outside of brain & spinal cord).
Schwann Cells/Neurolemmocytes
Blood-Brain Barrier—Sealing off of brain capillaries by astrocytes Prevents fluctuations (drastic changes) in ion levels (Na+, K+) inside brain which would interfere/disrupt the production of action potentials. Also prevents many toxic substances from crossing from the blood into the brain.
Astrocytes
Structure—-Have a star-shaped body and many “feet” that cover the blood vessels and neurons in the brain
Astrocytes
A _ _ _ _ is formed when one of two types of glial cells wraps around the axon of a neuron, forming concentric layers around it. Myelin, a _ _, is made inside this sheath.
myelin sheath
fat
Octopus-like, with as many as 15 “arms”
Oligodendrocytes:
_ _ _ _ allow severed (cut) neurons to grow back together (regenerate), making them the reason PNS neurons are capable of repair
(CNS neurons can’t regenerate/regrow)
Schwann cells
_ _ _ _ (Myelinated):
*Top speed of action potential (AP) is 300 mph
White Matter
_ _ _ _ (Unmyelinated):
*Ave. speed of AP is 2 mph
Gray Matter
_ _ Nerves (with a myelin sheath) are called white matter and are found in the cortex of spinal cord and the medulla of brain.
Myelinated
_ _ Nerves (without a myelin sheath) are called gray matter and are found in the medulla of spinal cord, the cortex of the brain, and as scattered nuclei within the brain.
Nonmyelinated
Demyelination occurs with hard plaques replacing the myelin sheaths; Impaired AP conduction leads to loss of coordination, muscle weakness, tremors, numbness, visual & speech impairments.
What diseases occcur when this happens?
Multiple Sclerosis & Lou Gehrig Disease
In white matter, the axon is NOT completely covered by the myelin sheath. Instead, there are small gaps
or _ _ _ _ _ _ where the axon is exposed.
Nodes of Ranvier
The myelin sheath actually insulates the axon against electricity. This means an action potential (AP) cannot move _ _ the myelin sheath and is forced to hop from node to node. This greatly _ _ the speed of the AP as it moves down the axon.
through
increases