Basale ganglia Flashcards

1
Q

functies basal ganglia

A
  • motoriek (vooral somatomotorisch systeem en oogbewegingen)
  • cognitie
  • emoties
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

skeletomotor loop

A
  • controle motoriek ledematen en gezicht
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

oculomotor loop

A

controle oogspieren

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

associatieve loop

A

cognitie, aandacht, planning doelgericht bewegen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

limbische loop

A

emoties, motivatie van gedrag

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

skeletomotor loop directe route

A

remming wordt geremd (disinhibitie) –> motorplan wordt uitgevoerd

lobus frontalis (cortex) –> + putamen –> - sunstantia nigra pars reticulata –> -thalamus (VA/VL) –> + cortex

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

skeletomotorloop indirecte route

A

dis-disinhibitie –> motorplan kan worden afgekeurd

lobus frontalis –> + putamen –> - globus pallidus –> - N. subthalamicus –> + substantia nigra pars reticulata –> thalamus –> cortex

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

parkinsons

A

geen dompamine –> directe route is het meest gevoelig voor dopamine –> minder activiteit –> meer invloed indirecte route –> inhibitie van motorplan

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Chorea bij Huntingtons

A

N. caudatus en daarna rest basale ganglia aangedaan –> geen projecties naar globus pallidus –> indirecte route aangedaan –> minder inhibitie

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Hemiballisme

A

N. subthalamica aangedaan –> indirecte route aangedaan –> minder inhibitie

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Reward system

A
  • VTA en N. accumbens

- dopamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly