Basal Ganglia Flashcards
Caudate nucleus + putamen
Striatum (striped appearance)
Nucleus accumbens alternate name
Ventral striatum
Putamen + globus pallidus
Lentiform nucleus
What is the ansa lenticularis
Outflow from globus pallidus; GABA-ergic projection to thalamus
What type of project (ex/in) is the Striatum to the GPi?
Inhbitory
What receptors on the Striatum do SN DA bind in the direct pathway?
D1 (excitatory)
What is the role of the STN in the indirect pathway
Excites the inhibitory neuron from the GPi to the thalamus, resulting in more inhibition
Which DA receptors do SN DA bind in the indirect pathway
D2; inhibits excitatory interneuron, decreasing the activation of the inhibitory projection from the striatum to the GPe
Goal of indirect pathway
Inhibit competing movements
Goal of direct pathway
Facilitate target-oriented movements
Describe blood supply to basal ganglia
Nucleus accumbens is the fusion of ___
Head of caudate and putamen
Where is the Substantia nigra located
Rostral midbrain – dark appearance
Which 2 fibre tracts form the thalamic fasciculus?
1) lenticular fasciculus and ansa lenticularis (GPi)
Which fibres travel in the subthalamic fasciculus
1) inhibitory projections from GPe to STN; excitatory projections from STN to GPi