Basal Ganglia

Question 1

What is the function of the putamen circuit?

Answer 1

executes motor activity patterns

Question 2

What is the function of the caudate circuit?

Answer 2

cognitive control of motor patterns

Question 3

All basal ganglia circuits to the cortex are _______ (excitatory/inhibitory).

Answer 3

inhibitory

Question 4

Damage to the GP causes _______.

Answer 4

athetosis (slow, involuntary, convoluted, writhing movements of the fingers, hands, toes, and feet)

Question 5

Damage to the ST causes _______.

Answer 5

hemiballismus

Question 6

Damage to the caudate causes ______.

Answer 6

chorea

Question 7

Damage to the putamen causes ______.

Answer 7

chorea

Question 8

Damage to the SN causes _____.

Answer 8

rigidity and tremor

Question 9

What causes parkinson’s disease?

Answer 9

degeneration of the pars compacta of the SN

Question 10

Describe the pathway in normal basal ganglia circuit and how that changes in Parkinson’s disease.

Answer 10

Question 11

What are the four cardinal characteristcis of parkinson’s disease?

Answer 11

Rigidity

Tremor (3-6 cycles/s)

Akinesia

Postural Instability

Question 12

What causes the rigidity and tremor seen in Parkinson’s disease?

Answer 12

unapposed corticospinal stimulation