Barrett’s Oesophagus (2) Flashcards
1
Q
What is it?
What is it a risk factor for?
What are its risk factors?
A
➊ Pre-malignant condition, where there’s a change of oesophageal epithelium from squamous to columnar
➋ Oesophageal adenocarcinoma
➌ • GORD
• Family hx
• Obesity
2
Q
What is the Metaplasia-Dysplasia-Carcinoma Sequence?
How is it monitored?
A
➊ In a small minority of patients with Barrett’s, the metaplastic (columnar) epithelium can progress to a dysplasia, and then an adenocarcinoma
N.B. Progression of Barrett’s into an Adenocarcinoma is NOT INEVITABLE
➋ Regular screening and biopsies to check for dysplasia
3
Q
How is it managed?
A
• PPI
• Ablation to allow for normal, healthy cells to form (only for those with some degree of dysplasia)
