Bariatric Anesthesia Flashcards
American Heart Association defines obesity as body weight what percent greater than the ideal body wt?
30%
Is obesity a disease?
Yes
BMI equation?
Wt (kg)/ht(m)^2
Overweight classification:
> 25
Obesity classification:
> 30
Extreme obesity classification:
> 40
Which BMI has coexisting comorbidities?
35
Super obese pt classification:
> 50
Obesity class 3 BMI
> 40
Obesity class 2 BMI:
35-39.9
Obesity class 1 BMI:
30-34.9
Overweight BMI:
25-29.9
Normal BMI:
18.5-24.9
For every 13.6 kg fat wt gain how many miles is that?
25 miles of neovascularization
0.1 L/min CO increase for how much of fat?
Every 1 kg of fat
Sympathetic activation contributes to obesity induced Na retention and HTN bc why?
Adrenergic blockade or renal denervation
What plays a key role in mediating obesity HTN?
Excess renal Na reabsorption
Recent observations suggest that what may be a partial link between excess wt gain and increased sympathetic activity?
Leptin and its multi interactions with other neuro chemical pathways in hypothalamus
What is the key role in the elevation of SNS?
Leptin
Does insulin stimulate SNS?
Yes
The ‘satiation hormone’ is made by adipose cells that helps to regulate energy balance by inhibiting hunger
Leptin
Leptin is opposed by the actions of the what other hormone?
Ghrelin (hunger hormone)
What do leptin levels in hypothalamus do in response to fasting and evoke profound changes in energy balance and hormone levels?
Fall rapidly
Adipose tissue source of pro-inflammatory molecules (4)
- Leptin
- Tumor necrosis factor alpha
- Ang II
- Interleukin-6
What is an important predictor of DM?
Decreased secretion of adiponectin
What is a signal-averaged ECG?
More detailed type of ECG